Results 171 to 177 of about 1,018 (177)

Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design

Acta Crystallographica Section F, Structural Biology Communications, 2019
Elany Barbosa da Silva, Elfriede Dall, Peter Briza   +2 more
exaly  

Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification

Bioorganic and Medicinal Chemistry, 2017
Saulo Fehelberg Pinto Braga, Luan Carvalho Martins, Elany Barbosa da Silva   +2 more
exaly  

Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas’ disease

Bioorganic and Medicinal Chemistry Letters, 2006
Kevin G Pinney, Mary Lynn Trawick
exaly  

Convergent synthesis and cruzain inhibitory activity of novel 2-(N′-benzylidenehydrazino)-4-trifluoromethyl-pyrimidines

Bioorganic and Medicinal Chemistry, 2008
Nilo Zanatta, Helio G Bonacorso, Marcos A P Martins   +2 more
exaly  

Synthesis and structure–activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain

European Journal of Medicinal Chemistry, 2015
Marcos Verissimo De Oliveira Cardoso, Gevanio Bezerra De Oliveira Filho, Diogo Rodrigo Magalhães Moreira   +2 more
exaly  

Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates

Bioorganic and Medicinal Chemistry, 2009
Nelilma C Romeiro, Gabriela Aguirre, Paola Hernández   +2 more
exaly  

Highly predictive hologram QSAR models of nitrile-containing cruzain inhibitors

Journal of Biomolecular Structure and Dynamics, 2017
Daniel G Silva, Geraldo Rodrigues Sartori, CARLOS A Montanari   +2 more
exaly