Results 151 to 160 of about 1,668 (161)

Cruzain

2011
Mohammed Sajid, Stephanie A. Robertson, Linda S. Brinen, James H. McKerrow   +3 more
openaire   +1 more source

Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification

Bioorganic and Medicinal Chemistry, 2017
Saulo Fehelberg Pinto Braga, Luan Carvalho Martins, Elany Barbosa da Silva   +2 more
exaly  

Synthesis and structure–activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain

European Journal of Medicinal Chemistry, 2015
Marcos Veríssimo de Oliveira Cardoso, Gevanio Bezerra de Oliveira Filho, Diogo Rodrigo Magalhaes Moreira   +2 more
exaly  

Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas’ disease

Bioorganic and Medicinal Chemistry Letters, 2006
Kevin G Pinney, Ming Zhou
exaly  

Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas’ disease

Bioorganic and Medicinal Chemistry Letters, 2015
R Jeffrey Neitz, Hai-Chao Xu, Somenath Chowdhury   +2 more
exaly  

Convergent synthesis and cruzain inhibitory activity of novel 2-(N′-benzylidenehydrazino)-4-trifluoromethyl-pyrimidines

Bioorganic and Medicinal Chemistry, 2008
Nilo Zanatta, Helio G Bonacorso, Marcos A P Ap Martins   +2 more
exaly  

Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates

Bioorganic and Medicinal Chemistry, 2009
Paola Hernández, Mercedes Belén González, Silvia Perez-Silanes   +2 more
exaly  

Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents

Bioorganic and Medicinal Chemistry, 2009
José Maurício dos Santos Filho, Ana C Leite, Diogo Rodrigo Magalhaes Moreira   +2 more
exaly  

2D QSAR and similarity studies on cruzain inhibitors aimed at improving selectivity over cathepsin L

Bioorganic and Medicinal Chemistry, 2008
Tudor I Oprea, Carlos A Montanari
exaly  

Application of bioisosterism in design of the semicarbazone derivatives as cruzain inhibitors: a theoretical and experimental study

Journal of Biomolecular Structure and Dynamics, 2017
Rafaela S Ferreira, Vinicius G Maltarollo   +1 more
exaly