Results 251 to 260 of about 133,701 (285)

Cryo-Electron Microscopy of Biological Samples

Ultrastructural Pathology, 2006
A brief summary of current cryo-electron microscopy methods for processing and imaging biological tissues is provided. The main emphasis is given to two preparation procedures: frozen-hydrated samples because of the remarkable success of cryo-electron crystallography in obtaining near atomic resolution of integral membrane proteins, and high-pressure ...
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Conventional Electron Microscopy, Cryo-Electron Microscopy and Cryo-Electron Tomography of Viruses

2013
Electron microscopy (EM) techniques have been crucial for understanding the structure of biological specimens such as cells, tissues and macromolecular assemblies. Viruses and related viral assemblies are ideal targets for structural studies that help to define essential biological functions.
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Cryo-electron Microscopy of Vitreous Sections

2013
More than 30 years ago two groups independently reported the vitrification of pure water, which was until then regarded as impossible without a cryoprotectant [1, 2]. This opened the opportunity to cryo-electron microscopy (cryo-EM) to observe biological samples at nanometer scale, close to their native state. However, poor electron penetration through
Petr, Chlanda, Martin, Sachse
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Cryo-Electron Microscopy of DNA

1994
Seeing is believing! Less than 10 years after the discovery of the double helical structure of the DNA, the development by Kleinschmidt and Zahn (Kleinschmidt and Zahn 1959) of a method for direct visualization of nucleic acids has been and remains one of the major achievement of electron microscopy.
J. Dubochet, J. Bednar, P. Furrer, A. Stasiak   +3 more
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Grid Preparation for Cryo-Electron Microscopy

2012
Once 2D crystals suitable for electron crystallography have been obtained, grid preparation for cryo-EM is a critical step in obtaining high-resolution structural information. Specimens have to be prepared in a manner that prevents dehydration and disruption of the crystals in the vacuum of the electron microscope.
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Cryo-electron microscopy

2023
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Cryo-Electron Microscopy

2008
W. Chiu, J.T. Chang, F.J. Rixon
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Editorial overview: Cryo-electron microscopy

Current Opinion in Structural Biology
Pilar, Cossio, Edward, Egelman
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Cryo-Electron Microscopy and Cryo-Electron Tomography of Viruses

2023
Daniel Luque, José R. Castón
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Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics

Nature, 2013
Gongpu Zhao, Juan R Perilla, Christopher R Aiken   +2 more
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