Results 161 to 170 of about 59,949 (213)

Advances in cryo-EM that have shaped mechanistic models of membrane-attack-complex assembly and regulation. [PDF]

IUCrJ
Noone DP, Bubeck D.
europepmc   +1 more source

Organizational and Functional Principles of the Obligate Respiratory Chain Supercomplex

Journal of the Chinese Chemical Society, EarlyView.
In this review we deliver a comprehensive structural analysis of the actinobacterial respiratory chain supercomplex and discuss the principles underlying the assembly of its supramolecular architecture. ABSTRACT Proton translocating respiratory chain complexes assemble into supramolecular structures in their native cellular environment, yet the ...
Wei‐Chun Kao, Nick Hiatt, Carola Hunte
wiley   +1 more source

Bioinspired Copper Sites for the Transformations of Greenhouse Gases Like Methane and Nitrous Oxide

Journal of the Chinese Chemical Society, EarlyView.
This review highlights the bioinspired catalytic systems containing copper sites that facilitate the conversions of methane and nitrous oxide to methanol and nitrogen, respectively. ABSTRACT The quest for benign catalysts for environmental remediation under ambient conditions for a sustainable future is fueling contemporary research.
Amarendra Nath Maity, Kiran Reddy Kanubaddi, Ragesh Nath Radhakrishnan, Shyue‐Chu Ke   +3 more
wiley   +1 more source

Improving Protein Structure Prediction Using Integrative Cryo-EM and Ion Mobility Mass Spectrometry Modeling. [PDF]

J Chem Theory Comput
Howard JB, Narayanasamy A, Lindert S.
europepmc   +1 more source

Correlating Mid‐Infrared Absorption With Radiative Efficiency in Passive Daytime Radiative Cooling Systems

Macromolecular Rapid Communications, EarlyView.
We establish a correlation between the mid‐IR photonic response of Passive Daytime Radiative Cooling systems and their thermal radiation performances, characterized within a dedicated setup that simulates the irradiance toward outer space under controlled and reproducible conditions.
Emma Spotorno, Paola Stagnaro, Lucia Conzatti, Simona Losio, Roberto Utzeri, Francesco Bisio   +5 more
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Interactive segmentation of membrane and membrane mimic densities in cryo-EM maps

Bharadwaj A, Veerbeek L, Jakobi AJ.
europepmc   +1 more source

Sub-2 Å cryo-EM structures of transcribing RNA polymerase II reveal critical roles of water molecules in catalysis. [PDF]

Mol Cell
Li Q, Yi G, Wu Y, Xu S, Chong J, Huang X, Zhang P, Wang D.   +7 more
europepmc   +1 more source

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay, Lynn C. Lunsonga, Peter E. Light, Khaled Barakat   +3 more
wiley   +1 more source

Visualizing the mechanism of quinol oxidation and inhibition of a <i>bd</i>-type oxidase using cryo-EM. [PDF]

Sci Adv
van der Velden TT, Kayastha K, Pelser F, Brünle S, Jeuken LJC.   +4 more
europepmc   +1 more source