Results 151 to 160 of about 59,949 (213)

High-resolution cryo-EM structures of small protein-ligand complexes near the theoretical size limit. [PDF]

Nat Commun
Park K, Yoo Y, Jeon H, Choi K, Kim H, Kwon E, Lim HH, Kim DY, No KT.   +8 more
europepmc   +1 more source

Lithium Metal Anode Fabrication: Methods, Challenges, and Strategies

EcoEnergy, EarlyView.
Schematic illustration of four representative fabrication techniques for thin lithium metal anodes: extrusion, molten lithium infusion, electroplating, and physical vapor deposition (PVD). ABSTRACT The pursuit of ultra‐high energy‐dense lithium‐metal batteries (LMBs) has reignited the drive to fabricate ultrathin high‐quality lithium metal anodes. This
Ji Hyun Baek, Mi Ji Kang, Ho Won Jang
wiley   +1 more source

Computational protein stability analysis of SCN1A missense variants reveals domain‐dependent stability patterns

Epilepsia Open, EarlyView.
Abstract Objective To determine whether computational protein‐stability predictions discriminate pathogenic from benign SCN1A missense variants, and to characterize the structural distribution of predicted destabilization among pathogenic variants. Methods On an AlphaFold3‐predicted Nav1.1 structure, FoldX, and Rosetta Cartesian ΔΔG were computed for a
Youngkyu Shim, Eungu Kang, Naeun Kwak, Suhyun Kim   +3 more
wiley   +1 more source

Cryo-EM image processing of amyloid filaments in RELION-5.1

Lövestam S, Shi J, Li D, Jamali K, Scheres SH.   +4 more
europepmc   +1 more source

Ultrathin liquid cells for microsecond time-resolved cryo-EM. [PDF]

Nat Commun
Curtis WA, Wenz J, Krüger CR, Barrass SV, Drabbels M, Lorenz UJ.   +5 more
europepmc   +1 more source

Artificial intelligence–driven decoupling structure–activity relationship for lithium‐ion batteries

InfoScience, EarlyView.
Artificial intelligence can efferently accelerate the high‐throughput screening of battery materials, the analysis of multiphase mechanisms, and the precise prediction of capacity and cycle life. This review systematically summarizes the applications of machine learning (ML) in decoupling the complex structure‐activity relationships of lithium‐ion ...
Tao Wang, Yuhang Meng, Tianhao Chen, Xiangfen Jiang, Yoshio Bando, Jinjue Zeng, Xuebin Wang   +6 more
wiley   +1 more source

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

iNew Medicine, EarlyView.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng, Wenhui Zhao, Min Wang, Xianwen Wang   +3 more
wiley   +1 more source

A Personal Perspective on Metalloprotein Structure and the Future of Macromolecular X‐Ray Crystallography

Journal of the Chinese Chemical Society, EarlyView.
While X‐ray crystallography has been the primary method for determining the structures of metalloproteins, cryoEM has taken over this role, illustrated by [4Fe4S]‐cluster containing proteins deposited in the Protein Data Bank. What will be the role for X‐ray crystallography as cryoEM and machine learning methods dominate the initial structural analysis?
Douglas C. Rees
wiley   +1 more source

Bayesian perspective for orientation determination in cryo-EM with application to structural heterogeneity analysis. [PDF]

Acta Crystallogr D Struct Biol
Xu S, Balanov A, Singer A, Bendory T.
europepmc   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source