Results 151 to 160 of about 55,954 (213)

Mapping the Conformational Landscape of DNA Minicircles Through Atomic Force Microscopy and Shape Space Analysis

Small, EarlyView.
An automated framework is presented for quantifying DNA conformational variability from atomic force microscopy (AFM) images. DNA backbones are reduced to spline representations and analyzed using cyclic Procrustes analysis to measure shape similarity across ensembles.
Laura Wiggins, Tobias A. Firth, Max C. Gamill, Thomas E. Catley, Agnes Noy, Jonathan M. Fogg, Lynn Zechiedrich, Alice L. B. Pyne   +7 more
wiley   +1 more source

Compostable and Recyclable Baroplastic Triblock Copolymers Enable Low‐Energy Polymer Processing

Small, EarlyView.
Baroplastic Poly(L‐lactide)‐block‐poly(ethylene glycol)‐block‐poly(L‐lactide) triblock copolymers enable ambient‐temperature processing under moderate pressure, reducing energy demand while preserving polymer integrity. The materials show rapid industrial compostability, effective chemical and physical recyclability, and compatibility with heat ...
Chengzhang Xu, Chengwei Yi, Emilia Fulajtar, Anja FRM Ramsperger, Julian Brehm, Christian Laforsch, Holger Schmalz, Sabine Rosenfeldt, Ulrich Mansfeld, Holger Kress, Andreas Möglich, Andreas Greiner, Seema Agarwal   +12 more
wiley   +1 more source

Cryo-EM structure of Chlamydomonas reinhardtii Photosystem I complexed with cytochrome c₆. [PDF]

Nat Commun
Ogawa Y, Mahapatra GP, Milrad Y, Schimpf M, Kurisu G, Hippler M, Schuller JM.   +6 more
europepmc   +1 more source

The photoswitchable ABAMIs for the future regulation of GWT1 in a spatiotemporal level

Smart Molecules, EarlyView.
The GWT1‐targeted azobenzene‐aminopyridine derivatives (ABAMIs), sensitive to the light at wavelengths from 365 to 520 nm, are separately developed as photochromic ligands to regulate bioactivity as well as the GWT1 functions. These molecules are smart tools in photopharmacological studies, giving an innovative method for understanding functional GWT1 ...
Qian Ding, Zongying Li, Zaiwei Xiao, Siting Zhang, Zimai Liu, Xiaoguang Shao, Zhong Li, Wen Fu, Xusheng Shao   +8 more
wiley   +1 more source

Explicit correction of severely non-uniform distributions of cryo-EM views. [PDF]

Acta Crystallogr D Struct Biol
Barchet C, von Loeffelholz O, Bahena-Ceron R, Klaholz BP, Urzhumtsev AG.   +4 more
europepmc   +1 more source

Functional Repurposing of Magnetic Nanoparticle‐Assisted Hyperthermia for Immune Cell Labelling and Tracking

Small Methods, EarlyView.
We propose mild‐MHT protocol for the quick internalization of magnetic nanoparticles (MNPs) by immune cells. The heat induced by MNPs under alternating magnetic field stimulate MNPs diffusion and cell membrane invagination, accelerating the cellular internalization of MNPs. ABSTRACT Immune cell therapies show promise in hematologic malignancies and are
Giulia E. P. Nucci, Chiara Vitale, Alessandro di Girolamo, Niccolò Silvestri, Stefano Persano, Lorenci Gjurgjaj, Cristina Bottino, Roberta Castriconi, Teresa Pellegrino   +8 more
wiley   +1 more source

Posidonia oceanica Leaves as a Natural Filler for Poly(Butylene Succinate‐Co‐Adipate) Composites: Characterization and Biodegradation Assessment in Seawater

Journal of Vinyl and Additive Technology, EarlyView.
This study shows that incorporating 5–10 wt.% Posidonia oceanica, with or without micro‐talc, in PBSA preserves thermal stability, modifying crystallization behavior, and maintains good filler dispersion and interfacial adhesion. Mechanical properties are moderately stiffened.
Chiara Pedrotti, Damiano Rossi, Giovanni Raimondi, Riccardo Gallorini, Miriam Cappello, Irene Anguillesi, Marco Sandroni, Patrizia Cinelli, Maurizia Seggiani   +8 more
wiley   +1 more source

Helical reconstruction of amyloids in cryoSPARC

Acta Crystallographica Section F, EarlyView.
We present practical guidelines for helical reconstruction of amyloid filaments in cryoSPARC, benchmarked against publicly available datasets. Our analysis defines current capabilities and limitations, and outlines optimization strategies to enable high‐throughput structural studies and therapeutic discovery.Amyloid‐mediated proteotoxicity underlies ...
Jan-Hannes Schaefer, Robert T. O'Neill, Joseph P. Donnelly, Evan T. Powers, Jeffery W. Kelly, Gabriel C. Lander   +5 more
wiley   +1 more source

Comparing cryo-EM structures of the vertebrate cardiac muscle thick filament. [PDF]

Biophys Rev
Craig R, Dutta D, Koubassova NA, Tsaturyan AK, Padrón R.   +4 more
europepmc   +1 more source

From atoms to a data bank: optimizing transferability of electron‐density symmetry

Acta Crystallographica Section A, EarlyView.
This work focuses on the electron density of atoms modeled with a multipolar approach. We investigate how the refinement of the multipole models with/without symmetry constraints and optimization of the orientation of the local coordinate system and pseudosymmetry assignment improves the accuracy of electron‐density representations for atoms and atom ...
Paulina Maria Rybicka, Marta Kulik, Vladislav Ignat'ev, Paulina Maria Dominiak   +3 more
wiley   +1 more source