Results 271 to 280 of about 6,313,615 (343)

CryoAtlas: A Large Curated Dataset and Unified Benchmark for Cryo-EM Atomic Model Building (Train Part 3)

Mingrui Li
openalex   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Cryo-EM structures of apo, agonist- and antagonist-bound heteromeric kainate receptors. [PDF]

Sci Adv
Zhou C, Segura-Covarrubias G, M'Kay Hoffman A, Tajima N.   +3 more
europepmc   +1 more source

Keeping It Native: Non‐Denaturing Approaches to Top‐Down Protein Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics and top‐down mass spectrometry approaches provide direct characterization of proteoforms; the specific molecular forms of proteins, including post‐translational modifications, truncations, alternative splicing, and sequence variants.
Michael Xiao, Edvaldo Vasconcelos Soares Maciel, Frederik Lermyte, Owen S. Skinner   +3 more
wiley   +1 more source

Cryo-EM structure of ex vivo Sup35 yeast prion and the factors defining prion phenotype. [PDF]

Nat Commun
Dergalev AA, Chesnokov YM, Burtseva AD, Mitkevich OV, Baymukhametov TN, Popov VO, Boyko KM, Kushnirov VV.   +7 more
europepmc   +1 more source

Cryo-EM advances in TDP-43 amyloid fibrils structure determination

Zhengdong Xu, Xi Chen, Wenjuan Yi
openalex   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Cryo-EM structures of biopsy-derived TTR fibrils in hereditary transthyretin amyloidosis. [PDF]

Nat Commun
Zheng Y, Liang J, Li Z, Liu Y, Chu X, Zhang S, Wang W, Bao J, Liu B, Ma C, Yin G, Deng J, Chi W, Meng L, Shi Y.   +14 more
europepmc   +1 more source

Enhance food plant diversity conservation and use through greater coordination between genebanks and botanic gardens

PLANTS, PEOPLE, PLANET, EarlyView.
Food plants are vital to human and planetary health, but their diversity is threatened, making food security, nutrition, and environmental goals more difficult to achieve. Food plant diversity conservation, research, and education can be enhanced through collaboration between sectors, including genebanks and botanic gardens, which possess complementary
Colin K. Khoury, Sarah Gora, Hannes Dempewolf, Mauricio Diazgranados, Alex C. McAlvay, Vania Azevedo, Sam Brockington, Ángela Cano, Daniel Carver, Carly Cowell, Peter Crane, Cary Fowler, Peter Giovannini, Luigi Guarino, Robbie Hart, Geoff Hawtin, Sarada Krishnan, Charlotte Lusty, Patricia Malcolm, Nan McCarry, Abby Meyer, Allison Miller, Ray Mims, Tara Moreau, Arshiya Noorani, Susan K. Pell, Juan Lucas Restrepo, Erin C. Riordan, Stefan Schmitz, Paul Smith, Charles Spillane, Alvaro Toledo, Raakel Toppila, Maarten van Zonneveld, Emily Warschefsky, Peter Wenzl   +35 more
wiley   +1 more source