Results 71 to 80 of about 9,042 (207)

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Silicone cryogel skeletons enhance the survival and mechanical integrity of hydrogel-encapsulated cell therapies

Science Advances
The transplantation of engineered cells that secrete therapeutic proteins presents a promising method for addressing a range of chronic diseases. However, hydrogels used to encase and protect non-autologous cells from immune rejection often suffer from ...
W. Jeang, Matthew A. Bochenek, Suman Bose, Yichao Zhao, Bryan M Wong, Jia-Wei Yang, A. L. Jiang, R. Langer, D. G. Anderson   +8 more
semanticscholar   +1 more source

Molecularly imprinted composite cryogel for albumin depletion from human serum

, 2012
A new composite protein-imprinted macroporous cryogel was prepared for depletion of albumin from human serum prior to use in proteom applications. Polyhydroxyethyl-methacylate-based molecularly imprinted polymer (MIP) composite cryogel was prepared with ...
Yavuz, HANDAN, DENİZLİ, ADİL, ANDAC, Muge, BAYDEMIR, Gozde   +3 more
core   +1 more source

A new metal-chelated cryogel for reversible immobilization of urease

, 2013
Poly(2-hydroxyethyl methacrylate-co-glycidyl methacrylate) [poly(HEMA-GMA)] cryogel was synthesized by cryopolymerization technique at frozen temperature. Iminodiacetic acid (IDA) was then attached covalently to the cryogel as a chelating agent.
Denizli A., Akduman B., Uygun M., Akgöl S.   +3 more
core   +2 more sources

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Surface‐Functionalized Poly(2‐Oxazoline)‐Based Grids Produced by Two‐Photon Polymerization as 3D‐Structured Hydrogels Promoting Cell Adhesion

Small, EarlyView.
Sidechain‐functionalized poly(2‐oxazoline) cross‐linkers were utilized to print grids with varying mesh sizes by two‐photon polymerization (2PP grids). The amino‐functionalized hydrogels were subsequently used to covalently couple the RGD‐containing peptide sequence GCWRGDSP (RGD) to the amino groups in the side chains. In cell adhesion tests with L929
Tim Hoffmann, David Pretzel, Steffi Stumpf, Lena‐Marie Kaspar, Florian Behrendt, Christiane Höppener, Aaron Reupert, Volker Deckert, Lothar Wondraczek, Michael Gottschaldt, Klaus Liefeith, Ulrich S. Schubert   +11 more
wiley   +1 more source

Molecularly imprinted cryogel for L-glutamic acid separation

, 2012
WOS: 000302607100019PubMed ID: 22275267A molecular recognition based L-glutamic acid (L-GLU) imprinted cryogel was prepared for L-GLU separation via chromatographic applications.
Adil Denizli, Bayram, Engin, Say, Ridvan, Say, Rıdvan, Cemil Aydoğan, Denizli, Adil, Muge Andaç, Engin Bayram, Rıdvan Say, Andaç, Muge, Aydoğan, Cemil   +10 more
core   +1 more source

Electron Beam-Induced Immobilization of Laccase on Porous Supports for Waste Water Treatment Applications

Molecules, 2014
The versatile oxidase enzyme laccase was immobilized on porous supports such as polymer membranes and cryogels with a view of using such biocatalysts in bioreactors aiming at the degradation of environmental pollutants in wastewater.
Elham Jahangiri, Senta Reichelt, Isabell Thomas, Kristin Hausmann, Dietmar Schlosser, Agnes Schulze   +5 more
doaj   +1 more source

From Fundamentals to Engineering Sustainable Triboelectric Materials: A Review of Cellulose Platforms

Small, EarlyView.
This review examines cellulose as a sustainable platform for triboelectric nanogenerators, linking molecular structure, surface chemistry, and material engineering to charge generation, retention, and dissipation. Native, regenerated, and nanocellulose materials, functionalization strategies, scalable manufacturing, and diverse applications are ...
Renyun Zhang, Dabo Chen, Jiayong Li, Peihong Wang   +3 more
wiley   +1 more source