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Blood Reviews, 2007
Cryoglobulinemia refers to the presence in serum of immunoglobulins that precipitate at a cold temperature. Type I cryoglobulins are single monoclonal immunoglobulins usually associated with haematological disorders. Types II and III are mixed cryoglobulins, composed of monoclonal or polyclonal IgM respectively, having rheumatoid factor activity that ...
Alessandra Tedeschi
exaly +3 more sources
Cryoglobulinemia refers to the presence in serum of immunoglobulins that precipitate at a cold temperature. Type I cryoglobulins are single monoclonal immunoglobulins usually associated with haematological disorders. Types II and III are mixed cryoglobulins, composed of monoclonal or polyclonal IgM respectively, having rheumatoid factor activity that ...
Alessandra Tedeschi
exaly +3 more sources
Hematology, 2005
Abstract Mixed cryoglobulinemia (MC) type II is a disorder characterized by circulating cold-precipitable immune complexes composed of polyclonal immunoglobulin IgG and monoclonal IgM rheumatoid factor (RF). The systemic vasculitis which characterizes the disease is caused by the deposition of immune complexes on the walls of small ...
M, Oliver +5 more
openaire +4 more sources
Abstract Mixed cryoglobulinemia (MC) type II is a disorder characterized by circulating cold-precipitable immune complexes composed of polyclonal immunoglobulin IgG and monoclonal IgM rheumatoid factor (RF). The systemic vasculitis which characterizes the disease is caused by the deposition of immune complexes on the walls of small ...
M, Oliver +5 more
openaire +4 more sources
Hematology/Oncology Clinics of North America, 1999
Cryoglobulinemia may be found in a spectrum of disorders spanning clear-cut-B-cell neoplastic states, in which cryoprecipitation manifests as ischemic or occlusive vasculopathy, to a variety of immune complex diseases, in which vasculitis or glomerulonephritis may occur.
A, Dispenzieri, P D, Gorevic
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Cryoglobulinemia may be found in a spectrum of disorders spanning clear-cut-B-cell neoplastic states, in which cryoprecipitation manifests as ischemic or occlusive vasculopathy, to a variety of immune complex diseases, in which vasculitis or glomerulonephritis may occur.
A, Dispenzieri, P D, Gorevic
openaire +2 more sources
2006
descrizione della crioglobulinemia mista: definizione, manifestazioni cliniche, patofisiologia, prognosi, trattamento, diagnosi ...
FERRI C, ZIGNEGO, ANNA LINDA, PILERI SA
+7 more sources
descrizione della crioglobulinemia mista: definizione, manifestazioni cliniche, patofisiologia, prognosi, trattamento, diagnosi ...
FERRI C, ZIGNEGO, ANNA LINDA, PILERI SA
+7 more sources
Human Pathology, 1983
A large number of disease states are characterized by cryoglobulinemia. Quantification and immunochemical classification of cryoglobulins in serum provide information of diagnostic and pathophysiologic utility. Thus, type I cryoglobulins consist of a monoclonal immunoglobulin of a single class and are associated with lymphoproliferative disorders, such
openaire +2 more sources
A large number of disease states are characterized by cryoglobulinemia. Quantification and immunochemical classification of cryoglobulins in serum provide information of diagnostic and pathophysiologic utility. Thus, type I cryoglobulins consist of a monoclonal immunoglobulin of a single class and are associated with lymphoproliferative disorders, such
openaire +2 more sources
2006
Mixed cryoglobulinemia (MC) includes:MC type II, composed by polyclonal IgGmonoclonal IgM, and MC type III, composed by polyclonal IgG-polyclonal IgM immune-complexes. MC may be secondary to various immunological,hematological, and infectiousd iseases, or it can represent a distinct disorder, the ‘essential’ MC.
FERRI, Clodoveo, MASCIA, Maria Teresa
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Mixed cryoglobulinemia (MC) includes:MC type II, composed by polyclonal IgGmonoclonal IgM, and MC type III, composed by polyclonal IgG-polyclonal IgM immune-complexes. MC may be secondary to various immunological,hematological, and infectiousd iseases, or it can represent a distinct disorder, the ‘essential’ MC.
FERRI, Clodoveo, MASCIA, Maria Teresa
openaire +2 more sources
Current Treatment Options in Oncology, 2000
1. Treatment of symptomatic cryoglobulinemia is exceedingly challenging due to the multisystemic nature of its presentation, the variability of its course, and the paucity of effective therapeutic options supported by randomized controlled clinical trials. 2. Patients with mild, relatively asymptomatic disease should be observed without introduction of
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1. Treatment of symptomatic cryoglobulinemia is exceedingly challenging due to the multisystemic nature of its presentation, the variability of its course, and the paucity of effective therapeutic options supported by randomized controlled clinical trials. 2. Patients with mild, relatively asymptomatic disease should be observed without introduction of
openaire +2 more sources
La Revue de medecine interne, 2008
Cryoglobulinemia are immune complexes that may induce systemic cryoglobulinemic vasculitis. Cryoglobulin may be an isolated biological abnormality or may induce clinical manifestations of a systemic vasculitis, involving the skin, the joints, the peripheral nerve system and the kidneys.During the last 15 years, major advances have been obtained after ...
P, Cacoub, D, Sène, D, Saadoun
openaire +1 more source
Cryoglobulinemia are immune complexes that may induce systemic cryoglobulinemic vasculitis. Cryoglobulin may be an isolated biological abnormality or may induce clinical manifestations of a systemic vasculitis, involving the skin, the joints, the peripheral nerve system and the kidneys.During the last 15 years, major advances have been obtained after ...
P, Cacoub, D, Sène, D, Saadoun
openaire +1 more source