Results 171 to 180 of about 166,403 (367)

Recent advances of the egg\'s freezing: An overview

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
It is now more than three decades since the first live birth from oocyte cryopreservation. At present, oocyte cryopreservation has become a major component of Assisted Reproductive technologies (ART).
Faranak Aghaz, Mozafar Khazaei
doaj  

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

open access: yesMovement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark   +8 more
wiley   +1 more source

The role of Alpine botanical gardens in integrating germplasm bank collections and mission

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
This study underscores the vital role of Alpine botanical gardens (ABGs) in safeguarding Europe's alpine biodiversity amid climate change and habitat loss. By acting as living laboratories and reservoirs of plant genetic resources, ABGs bridge ex situ and in situ conservation, supporting ecosystem resilience and informing restoration strategies.
Marco Canella   +19 more
wiley   +1 more source

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

open access: yesRare Metals, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang   +7 more
wiley   +1 more source

Collection and freezing of equine epididymal spermatozoa [PDF]

open access: yes, 2014
The epididymis and vas deferens store an important number of fertile spermatozoa called the extragonadal sperm reserves. These stored spermatozoa can be collected in an ultimate attempt to preserve viable spermatozoa of a critically ill or dying stallion.
Govaere, Jan   +5 more
core   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

open access: yesSmall, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen   +7 more
wiley   +1 more source

Mechanosensitive Cell‐Laden Shape‐Memory Scaffolds Engineered via Cryogelation

open access: yesSmall Structures, EarlyView.
GelMA‐based shape‐memory scaffolds encapsulating human adipose‐derived stem cells are fabricated via cryogelation, showing rapid recovery and high cell viability. Under cyclic compression, they promoted mechanotransduction gene expression, and composite formulations (collagen/GelMA, dECM/GelMA) retained robust shape‐memory, highlighting their promise ...
JaeYoon Lee   +4 more
wiley   +1 more source

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