Results 311 to 320 of about 168,582 (335)

New Insights Into Ginseng and Clove Supplementation: Alleviating Obesity by Reducing Leptin Resistance and Reshaping the Gut Microbiota

Food Frontiers, Volume 7, Issue 1, January 2026.
AEGC conferred substantial resistance to weight gain and reduced food intake. AEGC may alleviate LR by regulating the levels of LEP and ADP. AEGC elevated the diversity of gut microbiota and reconstructed the composition. Changes such as CAG‐873 in gut microbiota may be the reason why AEGC alleviates LR.
Weifeng Ni, Shen Yao, Shichao Li, Shichao Liu, Liwei Sun, Daqing Zhao, Zhengqi Dong, Siming Wang, Weinan Wang, Meichen Liu   +9 more
wiley   +1 more source

Glucose-Enhanced Cryopreservation of hCAR-T Cells: Improved Recovery and Reduced Apoptosis. [PDF]

Biomol Ther (Seoul)
Jung SE, Moon Y, Lim M, Jeong H, Seo H.
europepmc   +1 more source

Altered Inflammatory Signature in a C9ORF72 ‐ALS iPSC‐Derived Motor Neuron and Microglia Coculture Model

Glia, Volume 74, Issue 1, January 2026.
Established a C9ORF72 ALS microglia and motor neuron coculture model. Identified an altered inflammatory signature in C9ORF72 ALS microglia. Single‐cell RNA sequencing detected the removal of an LPS responsive microglia subpopulation. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder involving multiple cell types in ...
Yujing Gao, Jessica L. Brothwood, Harpreet Saini, Gregory A. O'Sullivan, Carla F. Bento, James M. McCarthy, Nicola G. Wallis, Elena Di Daniel, Brent Graham, Daniel M. Tams   +9 more
wiley   +1 more source

Alginate Hydrogel with Pluronic F-68 Enhances Cryopreservation Efficiency in Peach Germplasm. [PDF]

Gels
Bobrova O, Faltus M, Husak V, Zamecnik J, Tunklova B, Narozhnyi S, Bilavcik A.   +6 more
europepmc   +1 more source

IL21—STAT3 controls the pentose phosphate pathway to support metabolic reprogramming and tumor progression in chronic lymphocytic leukemia

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Studying how microenvironmental cues influence metabolic reprogramming can uncover mechanisms driving tumor progression. Using an in vitro model with proliferative stimuli of the in vivo lymph node niche (LN)—including interleukin‐21 (IL‐21)—we examined metabolic rewiring in chronic lymphocytic leukemia (CLL) cells. We found that the metabolic
Rosita Del Prete, Vjola Tusha, Helga Simon‐Molas, Virginia Anna Gazziero, Federica Nardi, Roberta Drago, Gaia Bartolini, Danilo Licastro, Margherita Malchiodi, Cristina Mariottini, Giuseppe Marotta, Giulio Caravagna, Stefano Bruscoli, Eric Eldering, Alessandro Gozzetti, Monica Bocchia, Anna Kabanova   +16 more
wiley   +1 more source

Enhancing post-thaw sperm quality in rams: quinic acid as a natural antioxidant. [PDF]

Front Vet Sci
Denk B, Kırıkkulak M, Güngör Ş, Gülhan MF, İnanç ME, Avdatek F, Yeni D, Taşdemir U.   +7 more
europepmc   +1 more source

Profiling of Extracellular Vesicles of Non‐Small Cell Lung Cancer Reveals Proteins Associated With Osimertinib Resistance

Journal of Extracellular Vesicles, Volume 15, Issue 1, January 2026.
Non‐invasive biomarkers are needed to further personalize EGFR tyrosine kinase inhibitor (EGFR TKI) osimertinib treatment in non‐small cell lung cancer (NSCLC) patients. By analysing the proteome of extracellular vesicles (EVs) isolated from an osimertinib resistant NSCLC cell line and from serum of patients given osimertinib in second line within the ...
Albano Cáceres‐Verschae, Petra Hååg, Sofia Joelsson, Per Hydbring, Bo Franzén, Ákos Végvári, Inger Johanne Z. Eide, Nupur Agarwal, Siddharth Sourabh Sahu, Fredrik Stridfeldt, Luigi De Petris, Apurba Dev, Simon Ekman, Odd Terje Brustugun, Rolf Lewensohn, Kristina Viktorsson   +15 more
wiley   +1 more source

Sperm Cell Membranes of Bulls and Bucks Associated with Sperm Fertility and Freezability. [PDF]

Animals (Basel)
Simsek S, Hitit M, Bodu M, Memili E.
europepmc   +1 more source

Oral Delivery of R‐spondin1‐Loaded Small Extracellular Vesicles Activates WNT Signalling Pathway to Accelerate Intestinal Injury Repair and Reverse Ageing

Journal of Extracellular Vesicles, Volume 15, Issue 1, January 2026.
Yang et al. demonstrated that HSPG mediate the loading of active R‐spondin1 protein onto the surface of small extracellular vesicles (evRSPO1). evRSPO1 induced WNT/β‐catenin activity in intestinal organoids and tissues, thereby regulating intestinal stem cells proliferation.
Lingyan Yang, Xu Wang, Xiyang Wei, Pei Yu, Yue Liu, Shixiang Wang, Yuefang Lin, Yue Yang, Ting Jiang, Zhiping Qiao, Jiaxiang Zhang, Shicheng Yu, Ye‐Guang Chen, Yun‐Shen Chan   +13 more
wiley   +1 more source

Impact of Cryopreservation Extenders on Epigenetic Changes in Bull Sperm: H19 and MEG3 Methylation. [PDF]

Vet Med Sci
Fouladvandi R, Masoudi AA, Sharafi M.
europepmc   +1 more source