Results 211 to 220 of about 7,136 (241)

Cryoprotectant agents for ovarian tissue vitrification: Systematic review

Cryobiology, 2021
Studies on the cryopreservation of ovarian tissue usually compare slow freezing versus vitrification and aim to optimize protocols, evaluate combinations or concentrations of cryoprotectant agents (CPAs), exposure time, and the addition of synthetic polymers.
Taynná El Cury-Silva, Monique E.G. Nunes, Maíra Casalechi, Fabio V. Comim, Jhenifer K. Rodrigues, Fernando M. Reis   +5 more
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Perfusion of rabbit kidneys with cryoprotective agents

Cryobiology, 1972
Abstract Rabbit kidneys were perfused at 5 or 37 °C for 2 hr with 2 m solutions of ethylene glycol, glycerol, or dimethylsulfoxide. It was found that each cryoprotectant caused an initial decrease in vascular resistance which was greater at 5 than at 37 °C but that dimethylsulfoxide caused a subsequent increase in resistance which was due to ...
openaire   +3 more sources

Thermal Expansion Measurements of Cryoprotective Agents

Advances in Bioengineering, 2003
As part of an ongoing effort to characterize the mechanical behavior of biological tissues in the cryogenic temperature range, the current study focuses on the thermal expansion measurements of cryoprotective agents. This study focuses particularly on the upper part of the cryogenic temperature range, where the cryoprotectant behaves like low viscous ...
Yoed Rabin, Ernest Bell
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A Dilution-Filtration System for Removing Cryoprotective Agents

Journal of Biomechanical Engineering, 2011
In most cryopreservation applications, the final concentrations of cryoprotective agents (CPAs) must be reduced to biocompatible levels. However, traditional methods for removing CPAs usually have disadvantages of operation complexity, time consumption, and ease of contamination, especially for the applications involving large volumes of cell ...
Weiping Ding, Zhiquan Shu, Shelly Heimfeld, Xiaoming Zhou, Jae Hyun Chung, Zhong Liu, Carolyn Liu, Pingan Du, Dayong Gao   +8 more
openaire   +3 more sources

Recent insights on the role of cryoprotective agents in vitrification

Cryobiology, 1989
In recent efforts to produce cryoprotective solutions which cause either complete, or almost complete, vitrification of the cell or tissue material, increasingly complex cocktails of solutes have invariably been used. Why some of these solutes are so much more effective in suppressing ice formation than other, related solutes has never been clear.
Maria Forsyth, Douglas R. MacFarlane
openaire   +2 more sources

Deep eutectic solvents as cryoprotective agents for mammalian cells

Journal of Materials Chemistry B, 2022
A deep eutectic solvent is an effective cryoprotective agent for several human cell lines.
Saffron J. Bryant, Miyah N. Awad, Aaron Elbourne, Andrew J. Christofferson, Andrew V. Martin, Nastaran Meftahi, Calum J. Drummond, Tamar L. Greaves, Gary Bryant   +8 more
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Permeation of several cryoprotectant agents into porcine articular cartilage

Cryobiology, 2009
Objective: Osteochondral allografting is an effective method to treat large osteochondral defects but difficulties in tissue preservation have significantly limited the application of this technique. Successful cryopreservation of articular cartilage (AC) could improve the clinical availability of osteochondral tissue and enhance clinical outcomes but ...
Rekieh, K., Abazari, A., Elliott, J.A., Jomha, N.M., Law, G.K., McGann, L.E.   +5 more
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The mechanism of action of low temperature and cryoprotective agents on immunoproteins

Cryobiology, 1978
Abstract The freezing and thawing of specific antitoxic serum proteins without a cryoprotective agent results in a reduction of titer. A freezing regimen has been chosen and the cryoprotectant PEO-400 has been added to prevent a reduction in activity of antitetanus serum after 6 months of storage in liquid nitrogen. The study of dielectric properties
A.A. Tsutsayeva, I.I. Gavrilova, V.M. Markova, L.V. Ivanov, G.G. Medvedyeva, Y.A. Itkin, V.A. Moiseyev, A.L. Markovsky, N.S. Pushkar   +8 more
openaire   +3 more sources

Identification of new cryoprotective agents for cultured mammalian cells

In Vitro, 1983
Thirty-one compounds have been identified that act as cryoprotective agents for cultured mammalian cells. Eight compounds were comparable to dimethylsulfoxide (DMSO) in cryoprotective effectiveness. Many of the cryoprotective compounds studied also (a) promote cell fusion and (b) induce cell differentiation in erythroleukemia and other cell systems ...
Robert J. Klebe, Melodee G. Mancuso
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Evaluation of ethylene glycol as a cryoprotective agent for blood platelets

Cryobiology, 1973
Abstract (1) Ethylene glycol appears to penetrate blood platelets rapidly and is nontoxic in high concentrations. (2) Higher concentrations are tolerated when potassium is present in the suspending medium. (3) Although ethylene glycol satisfied the basic theoretical criteria for a penetrating cryoprotectant, it failed to result in sufficiently high ...
Richard A. Kahn, Linda J. Flinton
openaire   +3 more sources