Results 71 to 80 of about 8,508 (215)

Time‐Resolved Native Mass Spectrometry Reveals Reversible Light‐Driven Oligomerization of Arabidopsis Cryptochrome 1 and Its Antagonism by BIC1

Angewandte Chemie International Edition, EarlyView.
Time‐resolved native mass spectrometry uncovers the blue‐light‐dependent kinetic mechanism of Arabidopsis CRY1 oligomerization, proceeding sequentially from monomers to dimers and tetramers. ATP promotes assembly, whereas BIC1 actively blocks and disassembles tetramers independent of light, providing mechanistic insight into the regulation of ...
Alicia Just, Nils Niemann, Petra Gnau, Dennis Kock, Thomas Heimerl, Stephan Kiontke, Lars‐Oliver Essen, Alfred Batschauer, Nina Morgner   +8 more
wiley   +1 more source

Structure Function Analysis of Mammalian Cryptochromes [PDF]

Cold Spring Harbor Symposia on Quantitative Biology, 2007
Members of the photolyase/cryptochrome family are flavoproteins that share an extraordinary conserved core structure (photolyase homology region, PHR), but the presence of a carboxy-terminal extension is limited to the cryptochromes. Photolyases are DNA-repair enzymes that remove UV-light-induced lesions.
Tamanini, Filippo, Chaves, I, Bajek, Monika, van der Horst, Bert   +3 more
openaire   +2 more sources

Diversity of Light Sensing Molecules and Their Expression During the Embryogenesis of the Cuttlefish (Sepia officinalis)

Frontiers in Physiology, 2020
Eyes morphologies may differ but those differences are not reflected at the molecular level. Indeed, the ability to perceive light is thought to come from the same conserved gene families: opsins and cryptochromes.
Morgane Bonadè, Atsushi Ogura, Erwan Corre, Yann Bassaglia, Yann Bassaglia, Laure Bonnaud-Ponticelli   +5 more
doaj   +1 more source

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

Chemistry – A European Journal, EarlyView.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami, Hikari Ozawa, Sohei Ito   +2 more
wiley   +1 more source

Magnetoreception through Cryptochrome May Involve Superoxide [PDF]

Biophysical Journal, 2009
In the last decades, it has been demonstrated that many animal species orient in the Earth magnetic field. One of the best-studied examples is the use of the geomagnetic field by migratory birds for orientation and navigation. However, the biophysical mechanism underlying animal magnetoreception is still not understood.
Solov'yov, Ilia, Schulten, Klaus
openaire   +3 more sources

Molecular Cloning and Expression Analysis of Cryptochrome Gene PsCRY2 in Tree Peony

Horticultural Plant Journal, 2016
Cryptochromes are blue/ultraviolet-A (UV-A) light receptors involved in regulating various aspects of plant growth and development. Investigations of the structure and functions of cryptochromes in plants have largely focused on herbaceous plants ...
Xiuxia REN, Shunli WANG, Jingqi XUE, Fuyong ZHU, Chuanjiao LIU, Xiuxin ZHANG   +5 more
doaj   +1 more source

Chronic sleep deprivation promotes drug‐resistant epilepsy via the BMAL1‐mTOR‐P‐gp axis

Epilepsia Open, EarlyView.
Abstract Objective The interplay between chronic sleep deprivation and drug‐resistant epilepsy (DRE) has gained increasing attention. Brain and muscle Arnt‐like protein 1 (BMAL1), which is implicated in sleep disturbance, has an unclear role in DRE. We aimed to investigate the role of BMAL1 in sleep deprivation‐induced DRE. Methods A pentylenetetrazole
Xiaomeng Wang, Rui Li, Yuzhu Zhang, Yi Hu, Jingjiao Chen, Sijia Tian, Dong Zhou, Xiaosa Chi   +7 more
wiley   +1 more source

Coherent chemical kinetics as quantum walks II: Radical-pair reactions in Arabidopsis thaliana

, 2015
We apply the quantum-walk approach recently proposed in arXiv:quant-ph-1506.04213 to a radical-pair reaction where realistic estimates for the intermediate transition rates are available.
Chia, A., Gorecka, A., Kaszlikowski, D., Kurzynski, P., Paterek, T.   +4 more
core   +1 more source

Profiling molecular and behavioral circadian rhythms in the non-symbiotic sea anemone Nematostella vectensis [PDF]

, 2015
© The Author(s), 2015. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Scientific Reports 5 (2015): 11418, doi:10.1038/srep11418.Endogenous circadian clocks are poorly ...
Alon, Shahar, Appelbaum, Lior, Elbaz, Idan, Levy, Oren, Oren, Matan, Simon-Blecher, Noa, Tarrant, Ann M.   +6 more
core   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source