Results 11 to 20 of about 54,207 (235)

Advances in cryptococcal infections-associated immunopathology and potential therapeutic strategies [PDF]

Frontiers in Pharmacology
Globally, the Cryptococcus species, particularly Cryptococcus neoformans and Cryptococcus gattii, have a significant impact on human health. Concurrent with the evolving epidemiology of cryptococcosis, it has now become evident how host immunity ...
Nadezhda Sachivkina, Sarmistha Saha, Regina Gurina, Olga Kuznetsova, Natallia Zhabo, Marina Avdonina, Olga Pilshchikova   +6 more
doaj   +2 more sources

Cerebral Venous Thrombosis due to Cryptococcus in a Multiple Sclerosis Patient on Fingolimod [PDF]

Case Reports in Neurology, 2022
Fingolimod is a disease-modifying treatment utilized in the treatment of relapsing-remitting multiple sclerosis. Fingolimod has been associated with an increased risk in herpes simplex and varicella infection in clinical trials.
Joel A. Kammeyer, Nicole M. Lehmann
doaj   +2 more sources

Phenotypic Switching of Cryptococcus neoformans and Cryptococcus gattii [PDF]

Mycopathologia, 2008
Microorganisms that live in fluctuating environments must constantly adapt their behavior to survive. The host constitutes an important microenvironment in opportunistic and primary fungal pathogens like Cryptococcus neoformans (C. neoformans) and Cryptococcus gattii (C. gattii).
Neena Jain, Bettina C. Fries
openalex   +4 more sources

Obligate sexual reproduction of a homothallic fungus closely related to the Cryptococcus pathogenic species complex

eLife, 2022
Sexual reproduction is a ubiquitous, ancient eukaryotic trait. While most sexual organisms have to find a mating partner, species as diverse as animals, plants, and fungi have evolved the ability to reproduce sexually without requiring another individual.
Andrew Ryan Passer, Shelly Applen Clancey, Terrance Shea, Márcia David-Palma, Anna Floyd Averette, Teun Boekhout, Betina M Porcel, Minou Nowrousian, Christina A Cuomo, Sheng Sun, Joseph Heitman, Marco A Coelho   +11 more
doaj   +1 more source

Neuroimaging of Cryptococcal Meningitis in Patients without Human Immunodeficiency Virus: Data from a Multi-Center Cohort Study

Journal of Fungi, 2023
Background: A clearer understanding is needed about the use of brain MRI in non-HIV patients with cryptococcal meningitis. Methods: Cerebral CT and MRI were studied in 62 patients in a multicenter study of cryptococcal meningitis in non-HIV patients.
Seher H. Anjum, John E. Bennett, Owen Dean, Kieren A. Marr, Dima A. Hammoud, Peter R. Williamson   +5 more
doaj   +1 more source

Cryptococcal chest wall mass and rib osteomyelitis associated with the use of fingolimod: A case report and literature review

Frontiers in Medicine, 2022
Being introduced in 2010, fingolimod was among the first oral therapies for relapsing multiple sclerosis (MS). Since that time, postmarketing surveillance has noted several case reports of various cryptococcal infections associated with fingolimod use ...
Kent Carpenter, Ali Etemady-Deylamy, Victoria Costello, Mohammad Khasawneh, Robin Chamberland, Robin Chamberland, Katherine Tian, Maureen Donlin, Brenda Moreira-Walsh, Emily Reisenbichler, Getahun Abate   +10 more
doaj   +1 more source

Opportunistic Fungal Infections in Immunocompromised Patients of a Tertiary Care Centre, Amritsar, India [PDF]

National Journal of Laboratory Medicine, 2022
Introduction: The incidence of opportunistic fungal infections has increased considerably in recent years. The clinical manifestations of these infections are non specific, and laboratory methods generally cannot diagnose infection at an initial ...
PAVNEET KAUR, SIMRANPREET KAUR, ARVINDER SINGH SOOD   +2 more
doaj   +1 more source

Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword

Journal of Infection in Developing Countries, 2023
Cryptococcal meningitis is an opportunistic infection associated with altered immunity. Immunomodulatory agent use in severe coronavirus disease 2019 (COVID-19) may predispose such infections.
Hilal W Abdessamad, Michel Achkar, Amal Al Zoghbi, Mohamad Fleifel, Abdul Rahman Ousta, Ahmad Kassar, Nadia L Samaha, Rita Nemr, Anna Farra, Jacques E Mokhbat, Rola Husni   +10 more
doaj   +1 more source

Cerebral Cryptococcosis Associated with CD4+ T-lymphocytopenia in Non-HIV Patients after SARS-CoV-2 Infection: Case Series in a Specialized Institute in Lima, Peru

Tropical Medicine and Infectious Disease, 2023
Cases of cryptococcosis have been reported in patients with COVID-19. The majority are in patients with severe symptoms or who received immunosuppressants. However, there is still no clear association between COVID-19 and cryptococcosis.
Juana M. Huamani-Córdova, Miguel Hueda-Zavaleta, Victor Vargas-Bellina, Lourdes Simbron-Ribbeck, Katty del Rosario Chong-Chinchay, Juan Carlos Gómez de la Torre, Vicente A. Benítes-Zapata   +6 more
doaj   +1 more source

Tobacco Hornworm (Manduca sexta) caterpillars as a novel host model for the study of fungal virulence and drug efficacy

Virulence, 2020
The two leading yeast pathogens of humans, Candida albicans and Cryptococcus neoformans, cause systemic infections in >1.4 million patients worldwide with mortality rates approaching 75%.
Naomi Lyons, Isabel Softley, Andrew Balfour, Carolyn Williamson, Heath E. O’Brien, Amol C. Shetty, Vincent M. Bruno, Stephanie Diezmann   +7 more
doaj   +1 more source