Results 71 to 80 of about 83,239 (230)
Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses [PDF]
, 2020 Cryptococcus neoformans is the most common disseminated fungal pathogen in AIDS patients, resulting in ∼200,000 deaths each year. There is a pressing need for new treatments for this infection, as current antifungal therapy is hampered by toxicity and/or
Hole, Camaron R +3 more
core +2 more sources
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Background Meningoencephalitis causes significant morbidity and mortality in children worldwide. Prompt diagnosis remains challenging, yet advances in molecular diagnostic technology have improved diagnostic performance. This study examined whether the introduction of the BioFire FilmArray meningitis/encephalitis (ME) multiplex panel impacted ...
Louisa Mary Churcher +4 more
wiley +1 more source
Cryptococcal Meningitis Diagnostics and Screening in the Era of Point-of-Care Laboratory Testing. [PDF]
, 2019 Over the past ten years, standard diagnostics for cryptococcal meningitis in HIV-infected persons have evolved from culture to India ink to detection of cryptococcal antigen (CrAg), with the recent development and distribution of a point-of-care lateral ...
Beyene, T +5 more
core +1 more source
Consumed by Abdominal Distention
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge +3 more
wiley +1 more source
The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1
Molecular Microbiology, EarlyView.A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen +3 more
wiley +1 more source
Memórias do Instituto Oswaldo Cruz, 2018 In Cryptococcus neoformans, nearly all genes are interrupted by small introns. In recent years, genome annotation and genetic analysis have illuminated the major roles these introns play in the biology of this pathogenic yeast. Introns are necessary for gene expression and alternative splicing can regulate gene expression in response to environmental ...
openaire +6 more sources
Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease. [PDF]
, 2014 UnlabelledCryptococcus spp. cause life-threatening fungal infection of the central nervous system (CNS), predominantly in patients with a compromised immune system.
Bautos, Jennifer M +7 more
core +2 more sources
Plant Biotechnology Journal, EarlyView.ABSTRACT Grey mould, caused by Botrytis cinerea, is a significant postharvest disease leading to substantial economic losses in the grape industry. This study investigated the regulatory mechanism of 3‐methyl‐1‐butanol (3M1B), a yeast volatile substance, on B. cinerea resistance in red grapes (Vitis vinifera L.).
Shunjie Zhai +7 more
wiley +1 more source
Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.Abstract A 10‐month‐old, neutered, male domestic shorthair cat with outdoor access was presented with a thoracic wound, severe respiratory distress, cachexia, dehydration and pleural effusion. Imaging confirmed bilateral pyothorax. Haematology showed marked neutrophilia with left shift, mild anaemia, thrombocytopenia and lymphocytosis.
Hugo Martínez‐Jarquin +5 more
wiley +1 more source