Results 51 to 60 of about 54,207 (235)

Multitrophic alpha and beta diversity of lake plankton across Canada

Oikos, EarlyView.
Anthropogenic environmental changes impact freshwater biodiversity globally. While biodiversity assessments in freshwater environments have traditionally focused on individual groups of organisms or trophic levels, considering patterns of ‘multitrophic biodiversity' across the food web provides a more comprehensive view of anthropogenic impacts and ...
Vincent Fugère, Cindy Paquette, Gillian K. Martin, Rebecca E. Garner, Yannick Huot, David A. Walsh, Beatrix E. Beisner   +6 more
wiley   +1 more source

Cytokine dynamics in the blood and cerebrospinal fluid of HIV/AIDS patients with cryptococcal meningitis receiving antifungal therapy

Frontiers in Cellular and Infection Microbiology
BackgroundCytokines in the serum and cerebrospinal fluid (CSF) are critical to the pathogenesis of HIV-associated cryptococcal meningitis (HCM). Previous studies focused on baseline cytokine levels, but changes during antifungal therapy are underexplored.
Rui Su, Shuwei Zhao, Jun Liu, Chongxi Li, Yuye Li, Yingkui Cao, Zhenghui Yang, Hongbin Li   +7 more
doaj   +1 more source

Cryptococcosis and Cryptococcus [PDF]

Mycopathologia, 2021
Elaine Cristina Francisco, Auke W. de Jong, Ferry Hagen   +2 more
openaire   +3 more sources

Melanogenesis in Cryptococcus neoformans [PDF]

Microbiology, 1988
Melanogenesis in Cryptococcus neoformans begins with the oxidation of dihydroxyphenylalanine by the enzyme phenol oxidase. The succeeding steps are very rapid. Two intermediates, dopachrome and 5,6-dihydroxyindole, have been isolated and characterized by high performance liquid chromatography. A pathway of melanin formation in C. neoformans is proposed,
I, Polacheck, K J, Kwon-Chung
openaire   +2 more sources

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

Novel molecular-based techniques of Cryptococcus identification in Cryptococcal meningitis: Recent advances and prospects

Journal of Advanced Biotechnology and Experimental Therapeutics
Meningitis is still a worldwide issue caused by Cryptococcus, also known as Cryptococcal meningitis. Cryptococcus infection is dependent on the host's immune condition.
Julian Julian, Robiatul Adawiyah, Sri Wahdini   +2 more
doaj   +1 more source

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance

mBio, 2019
Cryptococcal meningitis is a lethal disease with few therapeutic options. Induction therapy with fluconazole has been consistently demonstrated to be associated with suboptimal microbiological and clinical outcomes. Exposure to fluconazole causes dynamic
William Hope, Neil R. H. Stone, Adam Johnson, Laura McEntee, Nicola Farrington, Anahi Santoro-Castelazo, Xuan Liu, Anita Lucaci, Margaret Hughes, Jason D. Oliver, Charles Giamberardino, Sayoki Mfinanga, Thomas S. Harrison, John R. Perfect, Tihana Bicanic   +14 more
doaj   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Galactoxylomannans of Cryptococcus neoformans [PDF]

Infection and Immunity, 1992
Galactoxylomannans (GalXMs) from single isolates of Cryptococcus neoformans serotypes A, B, and D were isolated from culture supernatants and then purified by affinity, ion-exchange, and gel-filtration chromatography. GalXMs are a group of closely related complex polysaccharides.
P G, James, R, Cherniak
openaire   +2 more sources

Glycobiology of Human Fungal Pathogens: New Avenues for Drug Development

Cells, 2019
Invasive fungal infections (IFI) are an increasing threat to the developing world, with fungal spores being ubiquitous and inhaled every day. Some fungal species are commensal organisms that are part of the normal human microbiota, and, as such, do not ...
Danielle J. Lee, Holly O’Donnell, Françoise H. Routier, Joe Tiralongo, Thomas Haselhorst   +4 more
doaj   +1 more source