Results 51 to 60 of about 6,104 (218)

Heteroresistance of Cryptococcus gattii to Fluconazole [PDF]

Antimicrobial Agents and Chemotherapy, 2010
ABSTRACT We analyzed 71 clinical and environmental Cryptococcus gattii strains that had been isolated before or after the advent of azole antifungals to determine their level of heteroresistance to fluconazole (LHF). All strains of C.
A, Varma, K J, Kwon-Chung
openaire   +2 more sources

Eugenol‐Based Thiazole Derivatives Inhibit the MepA Efflux Pump in Staphylcoccus aureus

ChemistrySelect, Volume 11, Issue 3, 22 January 2026.
ABSTRACT Multidrug resistant (MDR) bacteria are considered critical priority pathogens by the World Health Organization (WHO). Considering the relevance of antibacterial drug development in this scenario, the present research study aimed to evaluate the antibacterial activity of eugenol‐based thiazole derivatives and analyze their potential to inhibit ...
Ray Silva de Almeida, Laís Regina dos Santos Folquitto, Priscilla Ramos Freitas, Ana Carolina Justino de Araujo, Saulo Relison Tintino, Jaime Ribeiro‐Filho, Cícera Datiane de Morais Oliveira‐Tintino, Gustavo Marinho Miranda, Ivaldo Francisco da Silva Junior, Diogo Teixeira Carvalho, Thiago Belarmino de Souza, Danielle Ferreira Dias, Carolina Bandeira Domiciano, Henrique Douglas Melo Coutinho   +13 more
wiley   +1 more source

Environmental Status of Cryptococcus neoformans and Cryptococcus gattii in Colombia

Journal of Fungi, 2021
The genus Cryptococcus comprises more than 80 species, including C. neoformans and C. gattii, which are pathogenic to humans, mainly affecting the central nervous system. The two species differ in geographic distribution and environmental niche.
Briggith-Nathalia Serna-Espinosa, Diomedes Guzmán-Sanabria, Maribel Forero-Castro, Patricia Escandón, Zilpa Adriana Sánchez-Quitian   +4 more
doaj   +1 more source

Infrared Spectroscopy as a Promising Tool for Diagnosing and Typing Human Pathogenic Fungi

Mycoses, Volume 69, Issue 1, January 2026.
ABSTRACT Fungal infections are increasingly recognised as a global health challenge, responsible for millions of cases annually and substantial mortality, especially in immunocompromised individuals. Yet, the diagnosis of these infections remains notoriously difficult, often delayed by slow culture‐based methods or hindered by the high cost and ...
Anthony G. J. Medeiros, Ayrton L. F. Nascimento, Luana Rossato, Daniel Assis Santos, Nalu Teixeira de Aguiar Peres, Reginaldo Goncalves de Lima Neto, Jacques F. Meis, Kássio M. G. Lima, Rafael Wesley Bastos   +8 more
wiley   +1 more source

Molecular epidemiological investigation of Cryptococcus spp. carried by captive koalas (Phascolarctos cinereus) in Japan

Microbiology Spectrum
Cryptococcus neoformans and Cryptococcus gattii cause cryptococcosis, a systemic mycosis that infects a wide range of species. Recent molecular biological investigations have allowed for the genotyping of these species, providing more detailed ...
Miki Omura, Kazuo Satoh, Takashi Tamura, Aya Komori, Koichi Makimura   +4 more
doaj   +1 more source

Clinical and microbiological characteristics of Cryptococcus gattii isolated from 7 hospitals in China

BMC Microbiology, 2020
Background Infection, even outbreak, caused by Cryptococcus gattii (C. gattii) has been reported in Canada and the United States, but there were sparsely-reported cases of C. gattii in China. Our interest in occurrence, clinical manifestation, laboratory
Liang Jin, Jing-Rong Cao, Xin-Ying Xue, Hua Wu, Li-Feng Wang, Ling Guo, Ding-Xia Shen   +6 more
doaj   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, Volume 12, Issue 48, December 29, 2025.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

Treatment of Cryptococcus gattii Infection Using Voriconazole.

Internal medicine (Tokyo, Japan), 2021
We previously reported a 39-year-old man who presented with pulmonary and cerebral Cryptococcus gattii (genotype VGIIa) infection and was successfully treated with liposomal amphotericin B and flucytosine induction therapy. Following induction therapy, oral fluconazole treatment was initiated as consolidation therapy. However, the patient complained of
Nakao, Makoto, Fujita, Kohei, Arakawa, Sousuke, Hayashi, Shuntaro, Tomita, Saori, Sato, Hidefumi, Muramatsu, Hideki   +6 more
openaire   +2 more sources

Cryptococcus gattii, No Longer an Accidental Pathogen? [PDF]

Current Fungal Infection Reports, 2012
Cryptococcus gattii is an environmentally occurring pathogen that is responsible for causing cryptococcosis marked by pneumonia and meningoencephalitis in humans and animals. C. gattii can form long-term associations with trees and soil resulting in the production of infectious propagules (spores and desiccated yeast).
Deborah J, Springer, Sujal, Phadke, Blake, Billmyre, Joseph, Heitman   +3 more
openaire   +2 more sources