Results 31 to 40 of about 62,210 (265)

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance. [PDF]

, 2019
Cryptococcal meningitis is a lethal disease with few therapeutic options. Induction therapy with fluconazole has been consistently demonstrated to be associated with suboptimal microbiological and clinical outcomes. Exposure to fluconazole causes dynamic
Aller, Altamirano, Arechavala, Bicanic, Bicanic, Boeva, Chang, Chen, Dannaoui, DePristo, Drusano, Harrison, Li, Longley, Loyse, Martin, Mayanja-Kizza, McKenna, Molloy, Mondon, Neely, Nixon, Nussbaum, Saag, Sionov, Sionov, Stone, Stott, Stott, Sudan, Wiederhold, Witt   +31 more
core   +1 more source

Cryptococcus neoformans infective endocarditis of native valves in an immunocompetent host

IDCases, 2018
With the emergence of Human immunodeficiency virus (HIV) and the resulting immunocompromised state, Cryptococcus neoformans infections have gained more importance in clinical practice.
Moni Roy, Sharjeel Ahmad, Ashish Kumar Roy   +2 more
doaj   +1 more source

Novel insights into host-fungal pathogen interactions derived from live-cell imaging [PDF]

, 2015
Acknowledgments The authors acknowledge funding from the Wellcome Trust (080088, 086827, 075470 and 099215) including a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377 and FP7-2007–2013 grant agreement HEALTH-F2-2010 ...
A Casadevall, AK Neumann, B Amulic, B Enjalbert, B Hube, BN Gantner, C Jiménez-López, C Sasse, C Tokarski, CC Sheth, CF Urban, CGJ McKenzie, CJ Chrisman, D Armstrong-James, D Ermert, D Liebl, D Vijayan, DA Silva da, DC Savage, DJ Krysan, E Moreno-Ruiz, EK Szabo, FM Rudkin, G Chamilos, G Vande Velde, GD Brown, GD Brown, H Ma, H Ma, I Rubin-Bejerano, IE Frohner, J Behnsen, J Chandra, J Maertens, J Perlroth, J Voigt, JM Bain, JM Tam, Judith Bain, K Konig, K Schäfer, K Seider, KM Brothers, L Romani, L Romani, Lars-Peter Erwig, LE Lewis, LE Lewis, LG Tilney, LY Ngo, M Alvarez, MC Lorenz, MG Netea, MJ Patterson, MS Lionakis, MS Lionakis, N Papon, NAR Gow, Neil A. R. Gow, O Uzun, O Zaragoza, P Martino, P Miramón, Q Qian, R García-Rodas, RA Drummond, RD Diamond, RI Lehrer, S Bruns, S El-Kirat-Chatel, S Keppler-Ross, S Mitra, SA Johnston, SC Cheng, SE Heinsbroek, V Aimanianda, Wellington, Y Luo   +77 more
core   +1 more source

A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var. grubii Type Strain Enhances Key Phenotypes Associated with Virulence

mBio, 2012
The accumulation of genomic structural variation between closely related populations over time can lead to reproductive isolation and speciation.
Carl A. Morrow, I. Russel Lee, Eve W. L. Chow, Kate L. Ormerod, Anita Goldinger, Edmond J. Byrnes, Kirsten Nielsen, Joseph Heitman, Horst Joachim Schirra, James A. Fraser   +9 more
doaj   +1 more source

Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]

, 2007
Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core   +4 more sources

Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses [PDF]

, 2020
Cryptococcus neoformans is the most common disseminated fungal pathogen in AIDS patients, resulting in ∼200,000 deaths each year. There is a pressing need for new treatments for this infection, as current antifungal therapy is hampered by toxicity and/or
Hole, Camaron R, Lam, Woei C, Lodge, Jennifer K, Upadhya, Rajendra   +3 more
core   +2 more sources

Diagnosis of Cryptococcus neoformans from the milk of goat using Multiplex PCR as diagnostic tool [PDF]

Mirror of Research in Veterinary Sciences and Animals, 2016
Cryptococcus neoformans (C. neoformans) is distributing globally. It is an opportunistic saprophytic fungal pathogen that appears as a dimorphic yeast-like fungus.
Shaimaa N. Yassein, Jenan M. Khalaf , Hayder M. Samaka 3   +2 more
doaj  

Dating the Cryptococcus gattii Dispersal to the North American Pacific Northwest. [PDF]

, 2018
The emergence of Cryptococcus gattii, previously regarded as a predominantly tropical pathogen, in the temperate climate of the North American Pacific Northwest (PNW) in 1999 prompted several questions.
Bodo Wanke, Chandler C. Roe, Colleen Lysen, Crystal M. Hepp, David M. Engelthaler, David P. Overy, Emilio DeBess, George R. Thompson, Hanna Oltean, J. Andrew Alspaugh, Jolene Bowers, Philippe J. Dufresne, Scott McBurney, Shawn R. Lockhart, Tom Chiller, Wieland Meyer   +15 more
core   +3 more sources

Evaluación de varias técnicas de extracción de ADN de Cryptococcus spp. a partir de muestras ambientales.

Biomédica: revista del Instituto Nacional de Salud, 2004
El género Cryptococcus comprende, al menos, 38 especies, pero sólo 3 se han informado como patógenas para el hombre y los animales: Cryptococcus laurentii, Cryptococcus albidus y Cryptococcus neoformans; esta última es la más frecuente.
Alexandra Castañeda, Juan McEwen, Marylin Hidalgo, Elizabeth Castañeda   +3 more
doaj   +1 more source

Synthesis, characterization and antifungal assessment of optically active bis-organotin compounds derived from (S)-BINOL diesters [PDF]

, 2019
Background: Organotin(IV) derivatives have appeared recently as potential biologically active metallopharmaceuticals exhibiting a variety of therapeutic activities.
Costantino, Andrea Rosana, Koll, Liliana Cristina, Mandolesi, Sandra Delia, Neudörfl, Jörg M., Ocampo, Romina Andrea, Svetaz, Laura Andrea, Zacchino, Susana Alicia Stella   +6 more
core   +1 more source