Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]
Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron +98 more
core +2 more sources
Diagnosis of Cryptococcus neoformans from the milk of goat using Multiplex PCR as diagnostic tool [PDF]
Cryptococcus neoformans (C. neoformans) is distributing globally. It is an opportunistic saprophytic fungal pathogen that appears as a dimorphic yeast-like fungus.
Shaimaa N. Yassein +2 more
doaj
Limited Activity Of Miltefosine In Murine Models Of Cryptococcal Meningoencephalitis And Disseminated Cryptococcosis [PDF]
Miltefosine is an alkyl phosphocholine with good oral bioavailability and in vitro activity against Cryptococcus species that has gained interest as an additional agent for cryptococcal infections.
Bocanegra, Rosie +5 more
core +1 more source
El género Cryptococcus comprende, al menos, 38 especies, pero sólo 3 se han informado como patógenas para el hombre y los animales: Cryptococcus laurentii, Cryptococcus albidus y Cryptococcus neoformans; esta última es la más frecuente.
Alexandra Castañeda +3 more
doaj +1 more source
Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance. [PDF]
Cryptococcal meningitis is a lethal disease with few therapeutic options. Induction therapy with fluconazole has been consistently demonstrated to be associated with suboptimal microbiological and clinical outcomes. Exposure to fluconazole causes dynamic
Aller +31 more
core +1 more source
Cryptococcus neoformans causes deadly mycosis primarily in AIDS patients, whereas Cryptococcus gattii infects mostly non-HIV patients, even in regions with high burdens of HIV/AIDS and an established environmental presence of C. gattii.
Michael J. Davis +10 more
doaj +1 more source
Capsules from pathogenic and non-pathogenic Cryptococcus spp. manifest significant differences in structure and ability to protect against phagocytic cells. [PDF]
Capsule production is common among bacterial species, but relatively rare in eukaryotic microorganisms. Members of the fungal Cryptococcus genus are known to produce capsules, which are major determinants of virulence in the highly pathogenic species ...
Glauber de S Araujo +12 more
doaj +1 more source
Synthesis, characterization and antifungal assessment of optically active bis-organotin compounds derived from (S)-BINOL diesters [PDF]
Background: Organotin(IV) derivatives have appeared recently as potential biologically active metallopharmaceuticals exhibiting a variety of therapeutic activities.
Costantino, Andrea Rosana +6 more
core +1 more source
Cryptococcus laurentii meningitis in a non-HIV patient
Cryptococcus species (other than Cryptococcus neoformans) have been labeled as saprophytic and nonpathogenic in immunocompetent individuals in the past.
Miriams T. Castro-Lainez +7 more
doaj +1 more source
An evolutionary perspective on zinc uptake by human fungal pathogens [PDF]
DW is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 102549/Z/13/Z).Peer reviewedPublisher ...
Wilson, Duncan
core +1 more source

