Results 61 to 70 of about 54,149 (255)

Cryptococcus neoformans Recovered From Olive Trees (Olea europaea) in Turkey Reveal Allopatry With African and South American Lineages

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Cryptococcus species are life-threatening human fungal pathogens that cause cryptococcal meningoencephalitis in both immunocompromised and healthy hosts.
Çağri Ergin   +9 more
doaj   +1 more source

Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans

open access: yesbioRxiv, 2017
Cryptococcus neoformans is an opportunistic fungal pathogen that causes approximately 625,000 deaths per year from nervous system infections. Here, we leveraged a unique, genetically diverse population of C.
C. Desjardins   +13 more
semanticscholar   +1 more source

Multiomics Reveal Associations Between CpG Methylation, Histone Modifications and Transcription in a Species That has Lost DNMT3, the Colorado Potato Beetle

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Despite lacking DNMT3, EM‐seq revealed CpG methylation in the Colorado potato beetle. CUT&Tag analysis showed an association of H3K36me3 and H3K27ac with transcription, with H3K36me3 mirroring CpG methylation, demonstrating epigenetic flexibility.
Zoe M. Länger   +6 more
wiley   +1 more source

Induction of Broad-Spectrum Protective Immunity against Disparate Cryptococcus Serotypes

open access: yesFrontiers in Immunology, 2017
Cryptococcosis is a fungal disease caused by multiple Cryptococcus serotypes; particularly C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no clinically available vaccine to prevent cryptococcosis.
Marley C. Caballero Van Dyke   +15 more
doaj   +1 more source

Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection

open access: yesScientific Reports, 2016
Cryptococcus neoformans is a significant fungal pathogen of immunocompromised patients. Many questions remain regarding the function of macrophages in normal clearance of cryptococcal infection and the defects present in uncontrolled cryptococcosis.
Aleksandra Bojarczuk   +11 more
semanticscholar   +1 more source

A Novel In Vitro Host−Pathogen Model for Felis catus and Sporothrix Zoonotic Species Investigation

open access: yesJournal of Basic Microbiology, EarlyView.
ABSTRACT Hyperendemic zoonotic sporotrichosis, attributed to Sporothrix brasiliensis, presents a significant public health challenge in Brazil. Cats exhibit severe symptoms and high fungal loads, though their susceptibility is unclear. Sporothrix schenckii can also cause feline disease, primarily seen in Asia.
Gabriele Barros Mothé   +10 more
wiley   +1 more source

Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

open access: yesNature Communications, 2016
Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis; however, treatment options remain limited. Here we report the construction of 264 signature-tagged gene-deletion strains for 129 putative kinases, and examine their ...
Kyung-Tae Lee   +28 more
semanticscholar   +1 more source

Evaluation of the Antifungal Properties of Azomethine‐Pyrazole Derivatives from a Structural Perspective

open access: yesChemistryOpen, EarlyView.
A series of azomethine‐pyrazole derivatives bearing a para‐substituted azo‐phenyl ring is straightforwardly prepared. The new compounds display an elevated antifungal activity against various Candida species and Cryptococcus neoformans strains. DFT and molecular docking calculations are used to determine possible routes of action through interactions ...
María Isabel Murillo   +8 more
wiley   +1 more source

Avaliação da produção de melanina por espécies de Cryptococcus em quatro diferentes meios de cultura Evaluation of melanin production by Cryptococcus species in four different culture media

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2007
A capacidade de Cryptococcus spp produzir melanina em meios contendo compostos fenólicos é amplamente utilizada na identificação destas espécies no laboratório.
Reginaldo dos Santos Pedroso   +3 more
doaj   +1 more source

Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans

open access: yesmBio, 2017
The ability to adapt to a changing environment provides a selective advantage to microorganisms. In the case of many pathogens, a large change in their environment occurs when they move from a natural setting to a setting within a human host and then ...
Kylie J. Boyce   +5 more
semanticscholar   +1 more source

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