Results 71 to 80 of about 177,470 (196)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

A new quantum cryptanalysis method on block cipher Camellia

IET Information Security, 2021
Symmetric cryptography is expected to be quantum safe when long‐term security is needed. Kuwakado and Morii gave a 3‐round quantum distinguisher of the Feistel cipher based on Simon's algorithm.
Yanjun Li, Hao Lin, Meng Liang, Ying Sun
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Message passing variational autoregressive network for solving intractable Ising models

Communications Physics
Deep neural networks have been used to solve Ising models, including autoregressive neural networks, convolutional neural networks, recurrent neural networks, and graph neural networks.
Qunlong Ma, Zhi Ma, Jinlong Xu, Hairui Zhang, Ming Gao   +4 more
doaj   +1 more source

A New Era of Cryptography : Quantum Cryptography

International Journal on Cryptography and Information Security, 2016
ABSTRACT Security is the first priority in today digital world for secure communication between sender and receiver. Various Cryptography techniques are developed time to time for secure communication. Quantum Cryptography is one of the latest and advanced cryptography technique, it is different from all other cryptography technique and more secure ...
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A novel multi-carrier visual cryptography scheme based on XOR and OR operations

Journal of King Saud University: Computer and Information Sciences
The conventional Visual Cryptography Scheme (VCS) relying solely on OR operations suffers from poor recovery quality and severe pixel expansion when implemented on physical transparencies.
Yuan Gao, Zhengxin Fu, Xiaopeng Li, Sensen Li, Bin Yu   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Improvement of the Minimal-Guess-Basis MILP Model and Its Application to ESF

IET Information Security
The guess-and-determine technique find wide applications in the recovery of unknown variables within given system of relations. The fundamental concept behind this technique involves guessing certain unknown variables and deducing the remaining ones ...
Lingchen Li, Zhi Qiao, Yiming Dai, Yongzhuang Wei, Tao Ye   +4 more
doaj   +1 more source