Results 71 to 80 of about 334,436 (368)
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Circuit-noise-resilient virtual distillation
Quantum error mitigation (QEM) is vital for improving quantum algorithms’ accuracy on noisy near-term devices. A typical QEM method, called Virtual Distillation (VD), can suffer from imperfect implementation, potentially leading to worse outcomes than ...
Xiao-Yue Xu+4 more
doaj +1 more source
Pseudorandom number generators based on neural networks: a review
Pseudorandom number generators are deterministic algorithms capable of producing sequences of numbers that appear sufficiently ”random,” and they find extensive applications across various domains such as cryptography, network security, communications ...
Xuguang Wu+6 more
doaj +1 more source
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source
A new quantum cryptanalysis method on block cipher Camellia
Symmetric cryptography is expected to be quantum safe when long‐term security is needed. Kuwakado and Morii gave a 3‐round quantum distinguisher of the Feistel cipher based on Simon's algorithm.
Yanjun Li, Hao Lin, Meng Liang, Ying Sun
doaj +1 more source
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
On Cheating Immune Secret Sharing [PDF]
The paper addresses the cheating prevention in secret sharing. We consider secret sharing with binary shares. The secret also is binary. This model allows us to use results and constructions from the well developed theory of cryptographically strong ...
Josef Pieprzyk, Xian-Mo Zhang
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
A Secure Data Sharing Model Utilizing Attribute-Based Signcryption in Blockchain Technology
With the rapid development of the Internet of Things (IoT), the scope of personal data sharing has significantly increased, enhancing convenience in daily life and optimizing resource management.
Chaoyue Song+3 more
doaj +1 more source