Results 61 to 70 of about 27,805 (273)

Systematic review and meta‐analysis of COVID‐19 association with human semen quality: Changes in semen parameters pre‐ and post‐COVID

UroPrecision, EarlyView.
Abstract Coronavirus disease (COVID‐19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which may infect the cells through binding with the angiotensin‐converting enzyme 2 (ACE2) receptors that can also be found in the male reproductive organs.
Wempy Supit, Tommy Supit, Sherryn Sherryn   +2 more
wiley   +1 more source

Renal Subcapsular xenografing of human fetal external genital tissue - A new model for investigating urethral development. [PDF]

, 2017
In this paper, we introduce our novel renal subcapsular xenograft model for the study of human penile urethral and clitoral development. We grafted fifteen intact fetal penes and clitorides 8-11 weeks fetal age under the renal capsules of gonadectomized ...
Baskin, Laurence, Cao, Mei, Cunha, Gerald, Isaacson, Dylan, Shen, Joel, Sinclair, Adriane, Yue, Xuan   +6 more
core   +2 more sources

Genomic technologies and the diagnosis of 46, XY differences of sex development

Andrology, EarlyView.
Abstract Differences/disorders of sex development can be caused by disruptions to the molecular and cellular mechanisms that control development and sex determination of the reproductive organs with 1:100 live births affected. Multiple genes are associated with 46, XY differences/disorders of sex development that can cause varying clinical phenotypes ...
Firman Idris, Andrew H. Sinclair, Katie L. Ayers   +2 more
wiley   +1 more source

Transscrotal transverse incision for the treatment of middle and low cryptorchidism in children: experience from 796 cases

BMC Surgery, 2020
Background The purpose of this study was to summarize our clinical experience with transscrotal transverse incision in the treatment of low and middle cryptorchidism in children.
Yun-jin Wang, Liu Chen, Qi-liang Zhang, Yu Lin, Xu Cui, Jian-cai Chen, Chao-ming Zhou   +6 more
doaj   +1 more source

Machine learning‐based classification of varicocoele grading: A promising approach for diagnosis and treatment optimization

Andrology, EarlyView.
Abstract Background Varicocoele is a correctable cause of male infertility. Although physical examination is still being used in diagnosis and grading, it gives conflicting results when compared to ultrasonography‐based varicocoele grading. Objectives We aimed to develop a multi‐class machine learning model for the grading of varicocoeles based on ...
Mehmet Vehbi Kayra, Ali Şahin, Serdar Toksöz, Mehmet Serindere, Emre Altıntaş, Halil Özer, Murat Gül   +6 more
wiley   +1 more source

miR-34c disrupts spermatogonial stem cell homeostasis in cryptorchid testes by targeting Nanos2

Reproductive Biology and Endocrinology, 2018
Background Cryptorchidism as a common genitourinary malformation with the serious complication of male infertility draws widespread attention. With several reported miRNAs playing critical roles in spermatogonial stem cells (SSCs), we aimed to explore ...
Zhenyu Huang, Dongdong Tang, Jingjing Gao, Xianming Dou, Peng Cheng, Dangwei Peng, Yao Zhang, Jun Mao, Li Zhang, Xiansheng Zhang   +9 more
doaj   +1 more source

Safety concerns of paternal drug exposure on fertility, pregnancy and offspring: An analysis based on the FDA adverse event reporting system

Andrology, EarlyView.
Abstract Background Growing evidence indicates that paternal condition significantly influences pregnancy outcomes and offspring health. However, assessing the safety of paternal drug exposure via randomized controlled trials poses ethical challenges, and relevant clinical studies consume a lot of resources to evaluate only a few drugs.
Yanbin Zeng, Wanlong Lin, Wei Zhuang
wiley   +1 more source

Criptorquidia na adolescência.

Acta Médica Portuguesa, 2011
An early investigation and management op cryptorchidism are essential for the diagnosis of associated pathologies, because intra-abdominal testis are associated with infertility and neoplasic risk.
Joana Ramos Pereira, Sérgio Neves, Filipa Leite, Cristina Baptista, Elisabete Santos, Alzira Ferrão, Carlos Figueiredo   +6 more
doaj   +1 more source

RNA sequencing profiles reveals progressively reduced spermatogenesis with progression in adult cryptorchidism

Frontiers in Endocrinology, 2023
IntroductionThe fertility of cryptorchidism patients who didn’t perform corrective surgery will decrease with age. Herein, we elucidate the histological alterations and underlying molecular mechanism in patients with an increase in the disease duration ...
Weihao Sun, Xinhui Zhang, Lei Wang, Guanyu Ren, Shuguang Piao, Chenghua Yang, Chenghua Yang, Zhiyong Liu, Zhiyong Liu   +8 more
doaj   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source