Results 81 to 90 of about 18,332 (236)
Andrology, EarlyView.ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam +7 more
wiley +1 more source
Genetic Alterations Associated With Cryptorchidism
, 2008 CONTEXT: Cryptorchidism is the most frequent congenital birth defect in male children and represents an important risk factor for infertility and testicular cancer.
FERLIN, ALBERTO
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Lifestyle in pregnancy and cryptorchidism in sons: a study within two large Danish birth cohorts
, 2018 Camilla Kjersgaard,1 Linn Håkonsen Arendt,1,2 Andreas Ernst,1 Morten Søndergaard Lindhard,2 Jørn Olsen,1,3 Tine Brink Henriksen,2 Katrine Strandberg-Larsen,4 Cecilia Høst Ramlau-Hansen1 1Department of Public Health, Section for
Strandberg-Larsen K +7 more
core
The true incidence of cryptorchidism in Denmark
, 2008 Purpose: Considerable controversy exists regarding the recently published high prevalence of cryptorchidism and the actual orchiopexy rate in Denmark. Therefore, we carried out another prevalence study.
Mette Breddam +7 more
core +1 more source
Andrology, EarlyView.ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec +18 more
wiley +1 more source
Testicular Cancer and Cryptorchidism
, 2013 The failure of testicular descent or cryptorchidism is the most common defect in newborn boys. The descent of the testes during development is controlled by insulin-like 3 peptide and steroid hormones produced in testicular Leydig cells, as well as by ...
Agoulnik, Alexander I. +5 more
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Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome
Andrology, EarlyView.ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor +6 more
wiley +1 more source
AnimalsYaks, a valuable livestock species endemic to China’s Tibetan plateau, have a low reproductive rate. Cryptorchidism is believed to be one of the leading causes of infertility in male yaks. In this study, we compared the morphology of the normal testis of
Qiu Yan +5 more
doaj +1 more source
Laboratory Animal Research, 2016 Transplantation of spermatogonial stem cells (SSCs) in experimental animal models has been used to study germ line stem cell biology and to produce transgenic animals. The species-specific recipient model preparation is important for the characterization
Won-Young Lee +6 more
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Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling [PDF]
, 2014 Cryptorchidism, or undescended testis, is a common male genital anomaly of unclear etiology. Hormonal stimulation of the developing fetal gubernaculum by testicular androgens and insulin-like 3 (INSL3) is required for testicular descent.
Robbins, Alan +10 more
core +1 more source