Results 61 to 70 of about 18,332 (236)

OCT 4 immunohistochemistry in postpubertal cryptorchidism

open access: yes, 2011
Patients with cryptorchidism are at an increased risk for germ cell testicular cancer. OCT 4 has been shown to be a sensitive and specific marker for some types of germ cell testicular cancer.
Nikola Knezevic   +5 more
core   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

open access: yesAndrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas   +6 more
wiley   +1 more source

miR-34c disrupts spermatogonial stem cell homeostasis in cryptorchid testes by targeting Nanos2

open access: yesReproductive Biology and Endocrinology, 2018
Background Cryptorchidism as a common genitourinary malformation with the serious complication of male infertility draws widespread attention. With several reported miRNAs playing critical roles in spermatogonial stem cells (SSCs), we aimed to explore ...
Zhenyu Huang   +9 more
doaj   +1 more source

Candidate Gene Discovery for Dog Cryptorchidism

open access: yes, 2008
Cryptorchidism is one of the most common developmental defects in purebred dogs. Single gene markers (called SNPs) are being used to investigate the associations in Siberian huskies between candidate genes (INSL3, LGR8, ESR1, HOXA10, MIS, CGRP and ...
Du, Zhiqiang   +3 more
core   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

open access: yesAndrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann   +9 more
wiley   +1 more source

Testicular neoplasia in undescended testes of cryptorchid boys-does surgical strategy have an impact on the risk of invasive testicular neoplasia?

open access: yesThe Turkish Journal of Pediatrics, 2004
We investigated whether or not surgical strategy has an impact on the risk of invasive testicular neoplasia in cases of cryptorchidism. We made a database study of the incidence of testicular neoplasia at surgery for cryptorchidism in childhood ...
Dina Cortes   +2 more
doaj  

Risk of cryptorchidism and hypospadias among boys of maternal hairdressers – a Danish population-based cohort study

open access: yesScandinavian Journal of Work, Environment & Health, 2013
OBJECTIVES: Pregnant hairdressers may be exposed to a mixture of chemicals in their working environment. The possible relationship between these chemical agents and male reproductive tract malformations has raised concern that the working environment of ...
Kristian Tore Jørgensen   +5 more
doaj   +1 more source

A survey of cryptorchidism among pediatric patients

open access: yes, 2021
Introduction: Cryptorchidism is one of the frequent congenital anomaly which can be seen in male external genitalia of pediatric patients. This may result in infertility, testicular trauma, malignancy, torsion, and strangulation of associated inguinal ...
Shilpa Gupta   +3 more
core  

Cryptorchidism: Novel genetic insights into CCDC149 mutations

open access: yesAndrology, EarlyView.
Abstract Background Cryptorchidism, characterized by the failure of one or both testes to descend into the scrotum, is a common congenital condition that can lead to infertility and increased risk of testicular cancer. CCDC149, a coiled‐coil domain‐containing protein, has been implicated in various developmental processes, but its role in the male ...
Shengrong Du   +8 more
wiley   +1 more source

Molecular Mechanisms of Syndromic Cryptorchidism: Data Synthesis of 50 Studies and Visualization of Gene-Disease Network

open access: yesFrontiers in Endocrinology, 2018
Background: Cryptorchidism is one of the most frequent congenital birth defects in male children and is present in 2–4% of full-term male births. It has several possible health effects including reduced fertility, increased risk for testicular neoplasia,
Kristian Urh   +5 more
doaj   +1 more source

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