Results 91 to 100 of about 25,988 (233)

Update on male reproductive endocrinology. [PDF]

, 2018
Practitioners of male reproductive and sexual medicine must have an intimate understanding of the physiology of male reproductive endocrinology, as such a knowledge is the cornerstone on which hormonal treatments are based.
Clavijo, Raul, Hsiao, Wayland
core   +1 more source

Environmental chemicals impact dog semen quality in vitro and may be associated with a temporal decline in sperm motility and increased cryptorchidism [PDF]

, 2016
Adverse temporal trends in human semen quality and cryptorchidism in infants have been associated with exposure to environmental chemicals (ECs) during development.
A Giwercman, A Kamarianos, AA Pacey, B Bush, BC Dunphy, D Balabanic, DJ Handelsman, E Carlsen, EJ Gubbels, F Chauvigne, G Dolf, G England, G Toft, G Toft, GC England, GCW England, HM Koch, HVU Brandsch, IC Oskam, IN Pathirana, J Axelsson, J Suominen, J Vitku, J-C Lu, JD Meeker, K Bay, K Choi, KA Boisen, L Robertson, LH Looijenga, M Rolland, MS Bloom, N Jorgensen, N Pant, N Pant, NE Skakkebaek, P Pocar, P Pocar, R Hauser, R Hauser, R Rozati, RL Wahl, RM Sharpe, RP Amann, S Ali, S Aquila, S Aquila, SC Smith, SH Swan, SH Swan, SM Rhind, SM Rhind, SW Seager, T Serrano, V Grieco, V Grieco, V Grieco, VR Kay, WG Foster, WV Holt, YX Wang   +60 more
core   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben, Anne Prinsen, Laetitia de Kort, Jetske van Breda   +3 more
wiley   +1 more source

Anogenital distance as a marker of androgen exposure in humans. [PDF]

, 2016
Abnormal foetal testis development has been proposed to underlie common disorders of the male reproductive system such as cryptorchidism, hypospadias, reduced semen quality and testicular germ cell tumour, which are regarded as components of a ...
Abbott, Acerini, Acerini, Adibi, Andersson, Asa, Ban, Bay, Berenbaum, Bergada, Boas, Bornehag, Bowman, Callegari, Carlsen, Castaño-Vinyals, Chamberlain, Cole, Corbier, Crouch, Dadze, Dean, Driesche, Eisenberg, Eisenberg, Eisenberg, Eisenberg, Eisenberg, Forest, Fowler, Francois, Gallavan, Golombok, Grinspon, Hack, Hauser, Hines, Hines, Hsieh, Hsieh, Huang, Hughes, Hughes, Hughes, Jain, Jensen, Jorgensen, Juul, Kosova, Kuiri-Hanninen, Kurtoglu, Lamminmaki, Lee, Litchfield, Liu, McDade, McIntyre, Mendiola, Mendiola, Mendiola, Miao, Michos, Milatiner, Mira-Escolano, Mitchell, Mylchreest, Papadopoulou, Papadopoulou, Parra, Pasterski, Pasterski, Pasterski, Pasterski, Romano-Riquer, Ruth, Safarinejad, Salazar-Martinez, Sathyanarayana, Sathyanarayana, Sathyanarayana, Singh, Skakkebaek, Suomi, Suzuki, Swan, Thanassoulis, Thankamony, Thankamony, Thorup, Toppari, Vafeiadi, Wallerand, Welsh, Welsh, Wilson, Wohlfahrt-Veje, Wolf, Yeh   +97 more
core   +1 more source

Spectrum of Hypogonadism and Its Management in Adolescents With Prader‐Willi Syndrome: A Retrospective Cohort Study Over 35 Years

Clinical Endocrinology, EarlyView.
ABSTRACT Context Adult data indicate that hypogonadism is underdiagnosed and undertreated in Prader‐Willi Syndrome (PWS). Objectives We aimed to describe the spectrum of pubertal development, and the diagnosis and treatment of hypogonadism in paediatric/adolescent patients with PWS. Design/Patients A retrospective cohort study of patients with PWS aged
Helen Nguyen, Geoffrey Ambler, Yoon Hi Cho   +2 more
wiley   +1 more source

Alterations in carbohydrate metabolism under cryptorchid condition in albino rats [PDF]

, 2009
Bilateral cryptorchidism was induced surgically in adult wistar strain albino rats and the carbohydrate metabolic pathway has been studied in testis, and sex accessory organs of both control and cryptorchid animals by estimating the marker enzymes and ...
Basha, S. Sadak, Bhaskar, M., Madhavi, YR. Radha, Madhuri, E., Sekhar, M Guru, Varma, K. Narasimha   +5 more
core   +2 more sources

Functional Data Strengthen Clinical Validation of PhenoScore Phenotype‐Guided AI for ANKRD11 Missense Variants

Clinical Genetics, EarlyView.
PhenoScore, an AI framework integrating facial recognition and clinical phenotype data, accurately identifies pathogenic ANKRD11 missense variants associated with KBG syndrome (AUC 0.95). Validated against functional data, PhenoScore outperforms REVEL and complements AlphaMissense, providing objective phenotypic evidence to reduce variants of uncertain
Evi Andriessen, Elke de Boer, Gholson J. Lyon, Bert B. A. de Vries, Charlotte W. Ockeloen, Alexander J. M. Dingemans   +5 more
wiley   +1 more source

Comparison of anogenital distance and correlation with vulvo-vaginal atrophy: a pilot study on premenopausal and postmenopausal women [PDF]

, 2018
OBJECTIVES: Anogenital distance (AGD) represents the space between labia posterior commissure and anus. This was pilot study to investigate how menopause and so lack of oestrogens affects AGD. METHODS: A total of 109 patients were enrolled.
Benedetti Panici, Pierluigi, Bracchi, Carlotta, Colagiovanni, Vanessa, Di Donato, Violante, Domenici, Lavinia, Lecce, Francesca, Marchetti, Claudia, Musella, Angela, Muzii, Ludovico, Palaia, Innocenza, Schiavi, Michele Carlo, Tomao, Federica   +11 more
core   +1 more source

Homozygous Loss‐of‐Function Variant in SLC20A1 Coding for Ubiquitous Phosphate Transporter PiT1 Is Associated With Multiple Developmental Abnormalities

Clinical Genetics, EarlyView.
Biallelic SLC20A1 loss‐of‐function variant causes a previously unrecognized multisystem developmental disorder. We report the first homozygous case presenting with tetralogy of Fallot, renal agenesis, polydactyly, and growth impairment. Transcriptome analysis of patient‐derived fibroblasts suggests significant dysregulation of pathways critical for ...
Eugénie Koumakis, Céline Huber, Wendy Chung, Christine Leroy, Pauline Parisot, Regis Gaudin, Mohamad Zaidan, Valérie Cormier‐Daire, Gérard Friedlander, Yoel Hirsch   +9 more
wiley   +1 more source

Pantaloon Hernia: Obstructed Indirect Component and Direct Component with Cryptorchidism

Case Reports in Surgery, 2016
Cryptorchidism is a condition in which one or both testes have not passed down into the scrotal sac. It is categorized as true undescended testis in which testes are present in the normal path of descent, and as ectopic testis, in which testes are ...
Mohan Kumar Kariappa, Vivek Harihar, Ashwini Rajareddy Kothudum, Vivekanand Kedarlingayya Hiremath   +3 more
doaj   +1 more source