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A Pumpless and Tubeless Microfluidic Device Enables Extended In Vitro Development of Cryptosporidium parvum. [PDF]
Gunasekera S +9 more
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Genetic crosses reveal genomic loci responsible for virulence in Cryptosporidium parvum infection
Shaw S +9 more
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Targeting Cryptosporidium parvum capture
Water Research, 2012Polymer microarrays offer a high-throughput approach to the screening and assessment of a large number of polymeric materials. Here, we report the first study of protozoan-polymer interactions using a microarray approach. Specifically, from screening hundreds of synthetic polymers, we identified materials that either trap the waterborne protozoan ...
Mei, Wu, Helen, Bridle, Mark, Bradley
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Adenosine kinase from Cryptosporidium parvum
Molecular and Biochemical Parasitology, 2006Analysis of the Cryptosporidium parvum genome demonstrates that the parasite cannot synthesize purines de novo and reveals that the sole route for purine salvage by the parasite is via adenosine kinase (CpAK). In order to initiate a biochemical characterization of CpAK and ultimately validate this apparently essential enzyme as a therapeutic target ...
Jon, Galazka +2 more
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Cellular biology of Cryptosporidium parvum
Parasitology Today, 1993With the emergence of Cryptosporidium parvum as a major pathogen encountered in human and veterinary clinical practice, a need for increased knowledge of the cellular- and immuno-biology of this Apicomplexan parasite has developed. Initial work has used paradigms taken from other Apicomplexans, especially Plasmodium, Toxoplasma and Eimeria, as a ...
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Cryptosporidium parvum studies with dairy products
International Journal of Food Microbiology, 1999Cryptosporidium parvum is a protozoan parasite capable of causing massive waterborne outbreaks. This study was conducted to model the transfer of C. parvum oocysts from contaminated water via food contact surfaces into yogurt and ice-cream, as well as to examine oocyst survival. Propidium iodide staining, combined with a direct immunofluorescence assay,
M Q, Deng, D O, Cliver
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Experimental Cryptosporidium parvum Infections in Chickens
The Journal of Parasitology, 1987Levine (1984, Journal of Protozoology 31: 9498) reviewed taxonomy and cross-transmission studies of members of the genus Cryptosporidium (Apicomplexa: Cryptosporidiidae). Based on the class of vertebrate that they infected, he considered that there were 4 valid species: Cryptosporidium muris Tyzzer, 1907, in mammals, C.
D S, Lindsay, B L, Blagburn, J A, Ernest
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Population genetics of Cryptosporidium parvum
Trends in Parasitology, 2004Among the apicomplexan parasites of medical interest, Cryptosporidium is the least studied. Consistent with other members of this phylum, the generally accepted life cycle of Cryptosporidium comprises a sexual phase during which gamete differentiation and fertilization occurs. This process can affect the population structure of this parasite because of
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Gaseous disinfection of Cryptosporidium parvum oocysts
Applied and Environmental Microbiology, 1996Purified oocysts of Cryptosporidium parvum suspended in approximately 400 microliters of phosphate-buffered saline or deionized water in microcentrifuge tubes were exposed at 21 to 23 degrees C for 24 h to a saturated atmosphere of ammonia, carbon monoxide, ethylene oxide, formaldehyde, or methyl bromide gas. Controls were exposed to air.
R, Fayer +3 more
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