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Population genetics of Cryptosporidium parvum

Trends in Parasitology, 2004
Among the apicomplexan parasites of medical interest, Cryptosporidium is the least studied. Consistent with other members of this phylum, the generally accepted life cycle of Cryptosporidium comprises a sexual phase during which gamete differentiation and fertilization occurs. This process can affect the population structure of this parasite because of
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Identification of invasion proteins of Cryptosporidium parvum

World Journal of Microbiology and Biotechnology, 2015
Host cell interactions and invasion by Cryptosporidium is a complex process mediated by zoites ligand-host cell receptors. Knowledge of proteins involved in this process will enable entry level inhibitors to be tried as therapeutic agents. In the present study, invasion proteins of Cryptosporidium parvum were studied in vitro.
Preeti, Singh   +9 more
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Experimental Cryptosporidium parvum Infections in Chickens

The Journal of Parasitology, 1987
Levine (1984, Journal of Protozoology 31: 9498) reviewed taxonomy and cross-transmission studies of members of the genus Cryptosporidium (Apicomplexa: Cryptosporidiidae). Based on the class of vertebrate that they infected, he considered that there were 4 valid species: Cryptosporidium muris Tyzzer, 1907, in mammals, C.
D S, Lindsay, B L, Blagburn, J A, Ernest
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Adenosine kinase from Cryptosporidium parvum

Molecular and Biochemical Parasitology, 2006
Analysis of the Cryptosporidium parvum genome demonstrates that the parasite cannot synthesize purines de novo and reveals that the sole route for purine salvage by the parasite is via adenosine kinase (CpAK). In order to initiate a biochemical characterization of CpAK and ultimately validate this apparently essential enzyme as a therapeutic target ...
Jon, Galazka   +2 more
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Cryptosporidium parvum: Is it Invincible?

Midsouth Entomologist, 2016
Cryptosporidium is a coccidian protozoan parasite that can affect mammals, reptiles, and birds. A coccidian is a single-celled protozoan that affects the epithelial lining of the intestinal walls of hosts it parasitizes. This parasite has a unique life cycle and can withstand common measures of sterilization. The infective oocyte stage is resistant and
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Effects of curcumin on Cryptosporidium parvum in vitro

Parasitology Research, 2009
Cryptosporidium parvum is a zoonotic protozoan parasite having peculiarities among the apicomplexa that could be responsible for its resistance to some drugs and disinfectants against coccidia. The awareness of Cryptosporidium as a health problem in man and animal is increasing and potent drugs are urgently needed.
M, Shahiduzzaman   +4 more
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The unusual mitochondrial compartment of Cryptosporidium parvum

Trends in Parasitology, 2005
Recent studies, including the Cryptosporidium parvum Genome Project, have provided evidence for a mitochondrial-derived compartment in this parasite. This organelle appears to lack a genome, and thus must be entirely dependent on nuclear-encoded proteins. Here, we review the evidence for such an organelle in C. parvum and its probable function.
Henriquez, F L   +4 more
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The response of Cryptosporidium parvum to UV light

Trends in Parasitology, 2005
Ultraviolet (UV) light is being considered as a disinfectant by the water industry because it appears to be very effective for controlling potential waterborne pathogens, including Cryptosporidium parvum. However, many organisms have mechanisms such as nucleotide excision repair and photolyase enzymes for repairing UV-induced DNA damage and regaining ...
Paul A, Rochelle   +3 more
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Cryptosporidium Parvum Gene Discovery

1999
Cryptosporidium parvum is a well-recognized cause of diarrhea in humans and animals throughout the world, and is associated with a substantial degree of morbidity and mortality in patients with acquired immunodeficiency syndrome (AIDS). At the present time, there is no effective therapy for treating or preventing infection with C. parvum.
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Natural History and Biology of Cryptosporidium parvum

Advances in Parasitology, 1998
The taxonomy of the genus Cryptosporidium remains ambiguous, because the current criteria for speciation are insufficient to validate the 6-8 named species. Cross-transmission experiments have shown varying and conflicting results, and the limited genetic data available do not necessarily support currently proposed species designations. The reasons for
S, Tzipori, J K, Griffiths
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