Results 1 to 10 of about 19,760,810 (228)

Pregnant sows immunized with Cryptosporidium parvum significantly reduced infection in newborn piglets challenged with C. parvum but not with C. hominis. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2022
BackgroundThe piglet is the only model to investigate the immunogenic relationship between Cryptosporidium hominis and C. parvum, the species responsible for diarrhea in humans.
Abhineet Sheoran   +7 more
doaj   +4 more sources

First identification of Cryptosporidium parvum virus 1 (CSpV1) in various subtypes of Cryptosporidium parvum from diarrheic calves, lambs and goat kids from France

open access: yesVeterinary Research, 2023
Cryptosporidium spp. remain a major cause of waterborne diarrhea and illness in developing countries and represent a significant burden to farmers worldwide.
Karim Tarik Adjou   +10 more
doaj   +1 more source

In Vitro Susceptibility of Cryptosporidium parvum to Plant Antiparasitic Compounds

open access: yesPathogens, 2022
Cryptosporidium parvum is a significant cause of watery diarrhoea in humans and other animals worldwide. Although hundreds of novel drugs have been evaluated, no effective specific chemotherapeutic intervention for C. parvum has been reported.
Sandamalie Ranasinghe   +4 more
doaj   +1 more source

MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection

open access: yesParasites & Vectors, 2022
Background MicroRNAs (miRNAs) are involved in the regulation of both the innate and adaptive immune response to Cryptosporidium parvum infection. We previously reported that C.
Fujie Xie   +11 more
doaj   +1 more source

Mechanisms of C. parvum-induced coagulopathy in mice [PDF]

open access: yesBritish Journal of Cancer, 1980
I.v. injection of Corynebacterium parvum (CP) into C57BL and BALB/c mice caused profound coagulation changes, featuring thrombocytopenia, decreased fibrinogen, increased fibrin/fibrinogen degradation products, and a concomitant microangiopathic haemolytic anaemia. These changes were greatest on the 9th day after CP, with recovery by Day 21.
Mitcheson, H D   +3 more
openaire   +2 more sources

NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses. [PDF]

open access: yesPLoS Pathogens, 2009
Cryptosporidium parvum is a protozoan parasite that infects the gastrointestinal epithelium and causes diarrheal disease worldwide. Innate epithelial immune responses are key mediators of the host's defense to C. parvum.
Rui Zhou   +5 more
doaj   +1 more source

Distribution and clinical manifestations of Cryptosporidium species and subtypes in HIV/AIDS patients in Ethiopia. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
BACKGROUND: Cryptosporidiosis is an important cause for chronic diarrhea and death in HIV/AIDS patients. Among common Cryptosporidium species in humans, C. parvum is responsible for most zoonotic infections in industrialized nations.
Haileeyesus Adamu   +7 more
doaj   +1 more source

Effect of C. Parvum on immunization with irradiated tumour cells [PDF]

open access: yesBritish Journal of Cancer, 1976
S.c. injection of tumour cells or small pieces of tumour irradiated to a dose of 22,000 rad evoked resistance to live challenge with the same tumour (a CBA strain fibrosarcoma induced with methylcholanthrene) 14 days later. This resistance was, however, over-ridden if the challenging inoculum was sufficiently large, and did not develop if the cells ...
Woodruff, M F   +3 more
openaire   +2 more sources

Population genetics of Cryptosporidium parvum subtypes in cattle in Poland: the geographical change of strain prevalence and circulation over time

open access: yesBMC Veterinary Research, 2022
Highlights C. parvum subtypes from the IIa allele family predominated in the tested cattle. The prevalence of C. parvum subtypes in cattle was breed-related. Dynamicity in the population C. parvum strains circulating in cattle was shown.
Agnieszka Kaupke, Artur Rzeżutka
doaj   +1 more source

C3a/C3aR Affects the Propagation of Cryptosporidium parvum in the Ileum Tissues of Mice by Regulating the Gut Barrier, Cell Proliferation, and CD4+ T Cell Main Effectors

open access: yesAnimals, 2023
Cryptosporidium parvum is an important zoonotic protozoon that threatens the health of humans and animals, but the interaction mechanisms between C. parvum and hosts are poorly understood.
Xin Yang   +7 more
doaj   +1 more source

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