Results 21 to 30 of about 19,760,810 (228)

Cryptosporidium parvum regulates HCT-8 cell autophagy to facilitate survival via inhibiting miR-26a and promoting miR-30a expression

open access: yesParasites & Vectors, 2022
Background Cryptosporidium parvum is an important zoonotic parasite, which not only causes economic losses in animal husbandry but also harms human health.
Heng Jiang   +8 more
doaj   +1 more source

Circular RNA ciRS-7 affects the propagation of Cryptosporidium parvum in HCT-8 cells by sponging miR-1270 to activate the NF-κB signaling pathway

open access: yesParasites & Vectors, 2021
Background Cryptosporidium is an important zoonotic pathogen responsible for severe enteric diseases in humans and animals. However, the molecular mechanisms underlying host and Cryptosporidium interactions are still not clear. Methods To study the roles
Yan-Ling Yin   +8 more
doaj   +1 more source

MCT-Dependent Cryptosporidium parvum-Induced Bovine Monocyte Extracellular Traps (METs) under Physioxia

open access: yesBiology, 2023
The apicomplexan protozoan parasite Cryptosporidium parvum is responsible for cryptosporidiosis, which is a zoonotic intestinal illness that affects newborn cattle, wild animals, and people all over the world.
Seyed Sajjad Hasheminasab   +5 more
doaj   +1 more source

Assessment of the Immune Response of Clinically Infected Calves to Cryptosporidium parvum Infection

open access: yesAgriculture, 2022
Cryptosporidium parvum (C. parvum) infection is one of the main causes of diarrhea in calves. The current study assessed the role of blood biomarkers (acute-phase proteins (APPs), procalcitonin, neopterin, cytokines, and oxidative stress in the ...
Wael El-Deeb   +7 more
doaj   +1 more source

Immune-complex disease in mice and humans given C. parvum [PDF]

open access: yesBritish Journal of Cancer, 1980
The present studies in mice and cancer-bearing patients, treated with C. parvum (CP) immunotherapy, were to determine the effects of CP on the production of immune complexes (IC) and associated disease. Using the Clq-binding assay, circulating immune complexes were detected in mice given a single high dose of CP (466 microgram) and repeated human ...
H D, Mitcheson   +4 more
openaire   +2 more sources

Characterization of a Fungal Modular Polyketide Synthase System Reveals an Unusual Strategy for Polyketide Chain Initiation

open access: yesAngewandte Chemie, EarlyView.
Fungal modular polyketide synthases (PKSs) remain largely unexplored. Functional characterization of the LasC/LasD assembly line established its role in strasseriolide C biosynthesis and suggested an unexpected strategy for chain initiation, in which a malonyl unit is transferred from the module 2 acyl carrier protein (ACP) domains to the loading ACP ...
Qiaolin Ji   +5 more
wiley   +2 more sources

Chitosan Protects Immunosuppressed Mice Against Cryptosporidium parvum Infection Through TLR4/STAT1 Signaling Pathways and Gut Microbiota Modulation

open access: yesFrontiers in Immunology, 2022
Cryptosporidium parvum infection is very common in infants, immunocompromised patients, or in young ruminants, and chitosan supplementation exhibits beneficial effects against the infection caused by C. parvum.
Sajid Ur Rahman   +5 more
doaj   +1 more source

Interferon-λ3 Promotes Epithelial Defense and Barrier Function Against Cryptosporidium parvum InfectionSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2019
Background & Aims: The epithelial response is critical for intestinal defense against Cryptosporidium, but is poorly understood. To uncover the host strategy for defense against Cryptosporidium, we examined the transcriptional response of intestinal ...
Sylvia H. Ferguson   +5 more
doaj   +1 more source

Effects of C. parvum on growth and induction of intracerebral tumours in mice [PDF]

open access: yesBritish Journal of Cancer, 1977
An investigation was made into the effect of Corynebacterium parvum therapy on cerebral tumours in mice. I.v. C. parvum caused a slight but significant increase in the survival of BALB/c mice injected intracerebrally (i.c.) with not more than 50 Meth A cells. C. parvum was most effective if given on the same day or 5 days after tumour. If this interval
Osborn, D E, Sadler, T E, Castro, J E
openaire   +2 more sources

Cryptosporidium canis n. sp. from domestic dogs [PDF]

open access: yes, 2001
Oocysts of Cryptosporidium, from the feces of a naturally infected dog and from an HIV-infected human, were identified as the previously reported canine genotype of Cryptosporidium parvum, hereafter referred to as Cryptosporidium canis n. sp.
Fayer, R.   +11 more
core   +1 more source

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