Results 21 to 30 of about 38,882,850 (250)

C3a/C3aR Affects the Propagation of Cryptosporidium parvum in the Ileum Tissues of Mice by Regulating the Gut Barrier, Cell Proliferation, and CD4⁺ T Cell Main Effectors

Animals, 2023
Cryptosporidium parvum is an important zoonotic protozoon that threatens the health of humans and animals, but the interaction mechanisms between C. parvum and hosts are poorly understood.
Xin Yang, Xuemei Wu, Shuang Huang, Qian Yao, Xi Chen, Junke Song, Yingying Fan, Guanghui Zhao   +7 more
doaj   +1 more source

Detection of Cryptosporidium parvum oocysts in calf fecal samples by direct immunofluorescence assay Detecção de oocistos de Cryptosporidium parvum em amostras fecais de bezerros pela reação de imunofluorescência direta

Revista Brasileira de Parasitologia Veterinária, 2011
The aim of this study was to produce a conjugate containing anti-Cryptosporidium parvum polyclonal antibodies and standardize a Direct Immunofluorescence Assay (DIF) for detecting C. parvum oocysts in fecal samples from calves. In order to obtain anti-C.
Weslen Fabricio Pires Teixeira, Willian Marinho Dourado Coelho, Cáris Maroni Nunes, Marcelo Vasconcelos Meireles   +3 more
doaj   +1 more source

Cryptosporidium Priming Is More Effective than Vaccine for Protection against Cryptosporidiosis in a Murine Protein Malnutrition Model. [PDF]

PLoS Neglected Tropical Diseases, 2016
Cryptosporidium is a major cause of severe diarrhea, especially in malnourished children. Using a murine model of C. parvum oocyst challenge that recapitulates clinical features of severe cryptosporidiosis during malnutrition, we interrogated the effect ...
Luther A Bartelt, David T Bolick, Glynis L Kolling, James K Roche, Edna I Zaenker, Ana M Lara, Francisco Jose Noronha, Carrie A Cowardin, John H Moore, Jerrold R Turner, Cirle A Warren, Gregory A Buck, Richard L Guerrant   +12 more
doaj   +1 more source

Clinical cases of zoonotic Cryptosporidium parvum (subtype IIdA15G1) infections in Korean goats

Veterinární Medicína, 2022
Cryptosporidium parvum is an enteric protozoan, which causes severe diarrhoea in a wide range of vertebrate hosts including ruminants and humans. C. parvum infections are responsible for immense economic losses to the livestock industry; furthermore, the
J Kim, K Lee, Roh SG, Kim HY, Kim JW, So BJ, Choi EJ   +6 more
doaj   +1 more source

Common occurrence of divergent Cryptosporidium species and Cryptosporidium parvum subtypes in farmed bamboo rats (Rhizomys sinensis)

Parasites & Vectors, 2020
Background Bamboo rats are widely farmed in southern China for meat, but their potential in transmitting pathogens to humans and other farm animals remains unclear. Methods To understand the transmission of Cryptosporidium spp.
Falei Li, Zhenjie Zhang, Suhui Hu, Wentao Zhao, Jianguo Zhao, Martin Kváč, Yaqiong Guo, Na Li, Yaoyu Feng, Lihua Xiao   +9 more
doaj   +1 more source

First report of Cryptosporidium andersoni and risk factors associated with the occurrence of Cryptosporidium spp. in pre-weaned native Korean calves with diarrhea

Frontiers in Veterinary Science, 2023
Cryptosporidium spp. are important enteric protozoan parasites that infect humans and other animals throughout the world. Cryptosporidium infection in cattle industry leads to substantial economic losses due to diarrhea, growth retardation, weight loss ...
Dong-Hun Jang, Hyung-Chul Cho, Yu-Jin Park, Jinho Park, Kyoung-Seong Choi   +4 more
doaj   +1 more source

Revisiting the reference genomes of human pathogenic Cryptosporidium species: reannotation of C. parvum Iowa and a new C. hominis reference

Scientific Reports, 2015
Cryptosporidium parvum and C. hominis are the most relevant species of this genus for human health. Both cause a self-limiting diarrhea in immunocompetent individuals, but cause potentially life-threatening disease in the immunocompromised.
J. P. Isaza, A. Galván, Víctor Polanco, Bernice Huang, A. Matveyev, M. Serrano, P. Manque, G. Buck, J. Alzate   +8 more
semanticscholar   +1 more source

Specific and quantitative detection and identification of Cryptosporidium hominis and C. parvum in clinical and environmental samples.

Experimental parasitology, 2013
Cryptosporidium is an enteric protozoan parasite that is resistant to inactivation by commonly used drinking water disinfectants. Between 2004 and 2010, it was responsible for 60% of all waterborne protozoan parasitic outbreaks reported worldwide.
Rong-Chang Yang, C. Murphy, Yong-Jik Song, J. Ng-Hublin, A. Estcourt, N. Hijjawi, R. Chalmers, Stephen J. Hadfield, A. Bath, Cameron Gordon, U. Ryan   +10 more
semanticscholar   +1 more source

Cryptosporidium parvum regulates HCT-8 cell autophagy to facilitate survival via inhibiting miR-26a and promoting miR-30a expression

Parasites & Vectors, 2022
Background Cryptosporidium parvum is an important zoonotic parasite, which not only causes economic losses in animal husbandry but also harms human health.
Heng Jiang, Xu Zhang, Xin Li, Xiaocen Wang, Nan Zhang, Pengtao Gong, Xichen Zhang, Yanhui Yu, Jianhua Li   +8 more
doaj   +1 more source

Circular RNA ciRS-7 affects the propagation of Cryptosporidium parvum in HCT-8 cells by sponging miR-1270 to activate the NF-κB signaling pathway

Parasites & Vectors, 2021
Background Cryptosporidium is an important zoonotic pathogen responsible for severe enteric diseases in humans and animals. However, the molecular mechanisms underlying host and Cryptosporidium interactions are still not clear. Methods To study the roles
Yan-Ling Yin, Ting-Li Liu, Qian Yao, Yu-Xin Wang, Xue-Mei Wu, Xue-Ting Wang, Xin Yang, Jun-Ke Song, Guang-Hui Zhao   +8 more
doaj   +1 more source