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Assessment of the Immune Response of Clinically Infected Calves to Cryptosporidium parvum Infection
Agriculture, 2022 Cryptosporidium parvum (C. parvum) infection is one of the main causes of diarrhea in calves. The current study assessed the role of blood biomarkers (acute-phase proteins (APPs), procalcitonin, neopterin, cytokines, and oxidative stress in the ...
Wael El-Deeb +7 more
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Parasites & Vectors, 2021 Background Cryptosporidium is an important zoonotic pathogen responsible for severe enteric diseases in humans and animals. However, the molecular mechanisms underlying host and Cryptosporidium interactions are still not clear. Methods To study the roles
Yan-Ling Yin +8 more
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Biology, 2023 The apicomplexan protozoan parasite Cryptosporidium parvum is responsible for cryptosporidiosis, which is a zoonotic intestinal illness that affects newborn cattle, wild animals, and people all over the world.
Seyed Sajjad Hasheminasab +5 more
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Immune-complex disease in mice and humans given C. parvum [PDF]
British Journal of Cancer, 1980 The present studies in mice and cancer-bearing patients, treated with C. parvum (CP) immunotherapy, were to determine the effects of CP on the production of immune complexes (IC) and associated disease. Using the Clq-binding assay, circulating immune complexes were detected in mice given a single high dose of CP (466 microgram) and repeated human ...
H D, Mitcheson +4 more
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Cellular and Molecular Gastroenterology and Hepatology, 2019 Background & Aims: The epithelial response is critical for intestinal defense against Cryptosporidium, but is poorly understood. To uncover the host strategy for defense against Cryptosporidium, we examined the transcriptional response of intestinal ...
Sylvia H. Ferguson +5 more
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The role of atypical MAP kinase 4 in the host interaction with Cryptosporidium parvum
Scientific Reports, 2023 Cryptosporidium parvum is an apicomplexan parasite that causes severe zoonotic diarrhea in humans and calves. Since there are no effective treatments or vaccines for infants or immunocompromised patients, it is important to understand the molecular ...
Nina Watanabe +6 more
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Effects of C. parvum on growth and induction of intracerebral tumours in mice [PDF]
British Journal of Cancer, 1977 An investigation was made into the effect of Corynebacterium parvum therapy on cerebral tumours in mice. I.v. C. parvum caused a slight but significant increase in the survival of BALB/c mice injected intracerebrally (i.c.) with not more than 50 Meth A cells. C. parvum was most effective if given on the same day or 5 days after tumour. If this interval
Osborn, D E, Sadler, T E, Castro, J E
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Frontiers in Immunology, 2022 Cryptosporidium parvum infection is very common in infants, immunocompromised patients, or in young ruminants, and chitosan supplementation exhibits beneficial effects against the infection caused by C. parvum.
Sajid Ur Rahman +5 more
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Immunological mechanisms in metastatic spread and the antimetastatic effects of C. parvum [PDF]
British Journal of Cancer, 1977 The effects of the host's immune response on metastatic spread was investigated by observing the numbers of pulmonary metastases that developed from an s.c. implant of the Lewis lung carcinoma in C57BL mice in which different cell populations had been suppressed. Macrophage function was impaired by treatment with silica (Si), cortisone acetate (CA), or
P D, Jones, J E, Castro
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Prevalence and molecular characterization of Cryptosporidium in goats across four provincial level areas in China. [PDF]
PLoS ONE, 2014 This study assessed the prevalence, species and subtypes of Cryptosporidium in goats from Guangdong Province, Hubei Province, Shandong Province, and Shanghai City of China. Six hundred and four fecal samples were collected from twelve goat farms, and the
Rongsheng Mi +8 more
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