Results 111 to 120 of about 5,245 (194)

The Emerging Role of Altered Cerebellar Synaptic Processing in Alzheimer’s Disease [PDF]

open access: yes, 2018
The role of the cerebellum in Alzheimer’s disease (AD) has been neglected for a long time. Recent studies carried out using transgenic mouse models have demonstrated that amyloid-b (Ab) is deposited in the cerebellum and affects synaptic transmission ...
Balbo, Ilaria   +6 more
core   +2 more sources

Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death [PDF]

open access: yes, 2015
Nanosized vesicles are considered key players in cell to cell communication, thus influencing physiological and pathological processes, including cancer.
Alessandro, R.   +11 more
core   +2 more sources

Cryptotanshinone Induces Apoptosis of HL-60 Cells via Mitochondrial Pathway [PDF]

open access: yes, 2014
Purpose: To test the effect of Cryptotanshinone (CPT), a natural  compound isolated from the plant Salvia miltiorrhiza Bunge, on human leukemic cell lines (HL-60).Methods: HL-60 cells were treated with CPT.
Ni, W, Qian, W, Tong, X
core   +2 more sources

Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice

open access: yesTumor Biology, 2017
Considerable attention has been paid to the introduction of novel naturally occurring plant-derived radiosensitizer compounds in order to augment the radiation efficacy and improve the treatment outcome of different tumors.
Amina M Medhat   +4 more
doaj   +1 more source

Cancer Phytotherapy: Recent Views on the Role of Antioxidant and Angiogenesis Activities [PDF]

open access: yes, 2017
Nowadays, increases in resistance of tumors to the current therapeutic agents have become a problematic issue. Therefore, efforts to discover new anticancer compounds with high sensitivity of cancer cells are extending.
Bahmani, Mahmoud.   +4 more
core  

Targeting SHP-1,2 and SHIP pathways – a novel strategy for cancer treatment? [PDF]

open access: yes, 2018
Well balanced levels of tyrosine phosphorylation, maintained by the reversible and coordinated actions of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs), are critical for a wide range of cellular processes including growth ...
Chevassut, T   +3 more
core   +1 more source

Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFkB pathways in cholangiocarcinoma cells

open access: yesDrug Design, Development and Therapy, 2017
Fayong Ke,1,2,* Zheng Wang,1,2,* Xiaoling Song,1,2 Qiang Ma,1,2 Yunping Hu,2 Lin Jiang,2 Yijian Zhang,2 Yingbin Liu,1,2 Yong Zhang,1 Wei Gong1,2 1Department of General Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai,
Ke FY   +9 more
doaj  

Effect of Harvest Time on Growth and Bioactive Compounds in Salvia miltiorrhiza

open access: yesPlants
Danshen (Salvia miltiorrhiza) is a perennial medicinal plant belonging to the Lamiaceae family. It is adapted to a wide range of soil pH with the potential to serve as an alternative crop in the United States.
Zhiheng Xing   +4 more
doaj   +1 more source

Terpenes and Flavonoids From Salvia apiana and Their Affinities to Cannabinoid and Opioid Receptors [PDF]

open access: yes, 2016
Salvia apiana (white sage, Lamiacae family) plant is native to southern California and parts of Mexico. Some Native American tribes local to this region consider S. apiana to be sacred and burn the leaves as incense for purification ceremonies. The plant
Hayes, Taylor
core   +1 more source

Cryptotanshinone promotes brown fat activity by AMPK activation to inhibit obesity

open access: yesNutrition Research and Practice
Activating brown adipose tissue (BAT) and browning of white adipose tissue (WAT) can protect against obesity and obesity-related metabolic conditions. Cryptotanshinone (CT) regulates lipid metabolism and significantly ameliorates insulin resistance.
Jie Ni   +5 more
openaire   +2 more sources

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