Results 91 to 100 of about 5,330 (211)

Preclinical and clinical examinations of Salvia miltiorrhiza and its tanshinones in ischemic conditions [PDF]

, 2006
Salvia miltiorrhiza (Labiatae, Laminaceae), danshen, is an annual sage mainly found in China and neighboring countries. The crude drug (dried root) and its preparations are currently used in China to treat patients suffering from heart attack, angina ...
Lien Eric, Yang Jun, Wang Rubin, Adams James   +3 more
core   +1 more source

WuYeLuGen Granule Attenuates Bleomycin‐Induced Pulmonary Fibrosis in Rats by Inhibiting the TGF‐β1/Smad Signaling Pathway and Epithelial–Mesenchymal Transition

Canadian Respiratory Journal, Volume 2026, Issue 1, 2026.
Background Pulmonary fibrosis is a chronic disease characterized by progressive interstitial lung changes affecting alveolar epithelial cells and pulmonary vessels. Following COVID‐19, it has emerged as a significant sequela in severe cases, often with a poor prognosis.
Jia-Wei Zeng, Li Lin, Yan-Jun Duan, Lipi Buch   +3 more
wiley   +1 more source

Cryptotanshinone inhibits breast cancer cell growth by suppressing estrogen receptor signaling [PDF]

Cancer Biology & Therapy, 2014
Estrogen receptor (ER) is a major therapeutic target for the treatment of breast cancer, because of the crucial role of estrogen signaling deregulation in the development and progression of breast cancer. In this study, we report the identification of a novel ERα binding compound, cryptotanshinone (CPT), by screening the CADD database.
Shanhu, Li, Hongtao, Wang, Liu, Hong, Wei, Liu, Fang, Huang, Jian, Wang, Peng, Wang, Xiaoqing, Zhang, Jianguang, Zhou   +8 more
openaire   +2 more sources

Hyperthermia Using Antibody-Conjugated Magnetic Nanoparticles and Its Enhanced Effect with Cryptotanshinone

Nanomaterials, 2014
Heat dissipation by magnetic nanoparticles (MNPs) under an alternating magnetic field can be used to selectively treat cancer tissues. Antibodies conjugated to MNPs can enhance the therapeutic effects of hyperthermia by altering antibody-antigen ...
Satoshi Ota, Naoya Yamazaki, Asahi Tomitaka, Tsutomu Yamada, Yasushi Takemura   +4 more
doaj   +1 more source

Methylation Landscapes of Cartilage in Hip Osteoarthritis

Genetics Research , Volume 2026, Issue 1, 2026.
Objective To elucidate different methylation landscapes between cartilage of femoral neck fracture and preserved and damaged cartilages in hip osteoarthritis (OA). Methods Genome‐wide DNA methylation data were acquired from two data sets in GEO database (GSE63106 and GSE63695), which were based on Illumina HumanMethylation450 BeadChip arrays.
Ruiyang Jiang, Maochun Wang, Guihua Tan, Jie Lv, Xiaoyu Jin, Yuan Liu, Rui Wu, Dongquan Shi, Yingkun Xu   +8 more
wiley   +1 more source

Icariin Alleviates Bleomycin‐Induced Idiopathic Pulmonary Fibrosis in Mice by Modulating the Gut–Lung Axis and Serum Metabolism

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease of uncertain etiology with few specific and effective therapeutic agents approved for its treatment. We examined the underlying processes and the impact of icariin (ICA) on a bleomycin‐induced pulmonary fibrosis model.
Ting Zhang, Weiyi Gong, Cheng Huang, Hongkai Wang, Baojun Liu, Dawei Cui   +5 more
wiley   +1 more source

Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects [PDF]

, 2015
Chronic liver dysfunction or injury is a serious health problem worldwide. Chronic liver disease involves a wide range of liver pathologies that include fatty liver, hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma.
Feng, Y, HONG, M, LI, S, TAN, HY, Tsao, GSW, Wang, N   +5 more
core   +2 more sources

Medicinal Plants for the Treatment of Hypertrophic Scars [PDF]

Hypertrophic scar is a complication of wound healing and has a high recurrence rate which can lead to significant abnormity in aesthetics and functions. To date, no ideal treatment method has been established.
Chen, J-Y, Rahman, K, Wang, S-J, Xin, H-L, Ye, Q, Zhang, H   +5 more
core   +1 more source

Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine [PDF]

, 2016
published_or_final_versio
Chan, SW, Cui, G, Hoi, MPM, Kwan, YW, Lee, SMY, Leung, GPH, Tseng, HHL, Zhou, X   +7 more
core   +1 more source

Investigation of the Regulatory Mechanism of Huazhuo Runzao Jiangqi Formula on Esophageal Cancer Utilizing Network Pharmacology, Molecular Docking, and In Vivo and In Vitro Experiments

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Background Esophageal cancer, a common digestive malignant neoplasm globally, poses significant health risks. Huazhuo Runzao Jiangqi (HRJ) formula, modified from the classic “Qige Powder” with additions and reductions, has shown clear efficacy in treating esophageal cancer and precancerous lesions in clinical practice and preliminary studies ...
Yun He, Huan-Fang Fan, De-Hui Li, Zi-Hui Liu, Yi-Ting Gu, Chang-Hui Han, Pan Ma, Na Guo, Xiao Wang, Yan Han, Irfan Ahmad   +10 more
wiley   +1 more source