Results 91 to 100 of about 4,552 (200)

Lycorine Attenuates Cardiac Fibrosis Through the Regulation of PYK2 Expression and Activity

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Lycorine (LYC), the most abundant monomeric compound from Lycoris radiata bulbs, possesses a range of biological activities, including antipulmonary fibrosis and cardioprotective effects. However, its role in regulating pathological cardiac remodeling, particularly in cardiac fibrosis, remains unclear.
Xiuxiu Gao, Ying Zhang, Dongzhe Li, Yufei Chen, Weimiao Qi, Shufang Cui, Chen Wang, Zhong Wang, Quanyi Wang, Abhishesh Mehata   +9 more
wiley   +1 more source

Cryptotanshinone Induces Apoptosis of HL-60 Cells via Mitochondrial Pathway [PDF]

, 2014
Purpose: To test the effect of Cryptotanshinone (CPT), a natural  compound isolated from the plant Salvia miltiorrhiza Bunge, on human leukemic cell lines (HL-60).Methods: HL-60 cells were treated with CPT.
Qian, W, Tong, X, Ni, W
core   +1 more source

Cryptotanshinone protects against oxidative stress in the paraquat-induced Parkinson's disease model

, 2023
[[abstract]]Parkinson's disease (PD) is a common neurodegenerative disorder associated with striatal dopaminergic neuronal loss in the Substantia nigra. Oxidative stress plays a significant role in several neurodegenerative diseases.
Sun, Jui-Ming;Sun, Jui-Ming;Agarw, Surbhi;Agarwal, Surbhi;Dnyan, Tushar;Desai, Tushar Dnyaneshwar;Ju, Da-Tong;Ju, Da-Tong;Ch, Yung-Ming;Chang, Yung-Ming;Shih-Chieh, L;Liao, Shih-Chieh;Tsung-Jung, H;Ho, Tsung-Jung;Yeh, Yu-Lan;Yeh, Yu-Lan;Kuo, Wei-Wen;Kuo, Wei-Wen;Lin, Yu-Jung;Lin, Yu-Jung;黃志揚;Huang, Chih-Yang
core  

Enhancing Metabolic Engineering in Medicinal Plants Through Prime Editing

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2858-2860, May 2026.
Haomiao Yu, Xiao Feng, Xiaohang Zheng, Xiao Wang, Wenxin Zheng, Zhizhou Zhang, Yuanyuan Jiang, Ruiwu Yang, Li Zhang, Zhaohui Zhong   +9 more
wiley   +1 more source

Supplemental Material, sj-pdf-1-het-10.1177_09603271211009954 - Developmental toxicity of cryptotanshinone on the early-life stage of zebrafish development

, 2021
Supplemental Material, sj-pdf-1-het-10.1177_09603271211009954 for Developmental toxicity of cryptotanshinone on the early-life stage of zebrafish development by C Wang, T Wang, B-W Lian, S Lai, S Li, Y-M Li, W-J Tan, B Wang and W Mei in Human ...
B-W Lian (11324967), Y-M Li (11324970), B Wang (805040), W Mei (11324976), S Lai (9977078), T Wang (4263634), W-J Tan (11324973), C Wang (4703686), S Li (5107748)   +8 more
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Ethosomes Loaded with Cryptotanshinone for Acne Treatment through Topical Gel Formulation - Fig 3

, 2016
Influence of cryptotanshinone loaded ethosomal gel on epidermis thickness (A) and lymphatic cell numbers in a radon area (10 μm×10 μm) of dermis (B).
Ke Ma (260231), Zhenwei Yu (3148452), Gang Han (127634), Hongyan Lv (3148455)   +3 more
core   +1 more source

Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice

Tumor Biology, 2017
Considerable attention has been paid to the introduction of novel naturally occurring plant-derived radiosensitizer compounds in order to augment the radiation efficacy and improve the treatment outcome of different tumors.
Amina M Medhat, Khaled Sh Azab, Mahmoud M Said, Neama M El Fatih, Nermeen M El Bakary   +4 more
doaj   +1 more source

Effects and mechanisms of Cryptotanshinone on rats with adjuvant arthritis.

Chinese medical journal, 2012
Cryptotanshinone (CT) is the major active constituent of Salvia miltiorrhiza Bunge. The present study was carried out to investigate the effects of CT on rats with adjuvant arthritis (AA).AA was induced by the metatarsal footpad injection with complete Freund's adjuvant in male Sprague-Dawley rats.
Fu-Lin, Zheng, Yan, Chang, Xiao-Yi, Jia, Min, Huang, Wei, Wei   +4 more
openaire   +1 more source

Cryptotanshinone reverses reproductive and metabolic disturbances in prenatally androgenized rats via regulation of ovarian signaling mechanisms and androgen synthesis

, 2011
This trial explores 1) prenatally androgenized (PNA) rats as a model of polycystic ovary syndrome (PCOS) and 2) reproductive and metabolic effects of cryptotanshinone in PNA ovaries.
Yongyan Wang, Wang, Yongyan, Zhang, Yuehui, Xinming Yang, Haixue Kuang, Kuang, Haixue, Chun Sik Bae, Elisabet Stener-Victorin, Yang, Xinming, Hou, Lihui, Bae, Chun Sik, Yuehui Zhang, Stener-Victorin, Elisabet,, Wu, Xiaoke, Xiaoke Wu, Lihui Hou   +15 more
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Targeting the STAT3/Th17 Pathway with Cryptotanshinone Reduces Lung Inflammation and Structural Alterations in Experimental COPD

COPD involves progressive airflow limitation driven by chronic inflammation, largely triggered by cigarette smoke. Disease progression is linked to heightened Th17/IL-17 responses, with STAT3 playing a key regulatory role.
Franciele Jesus Lima, Leticia de Paula Costa Mattos, Cintia do Nascimento Silva, Leandro do Nascimento Camargo, Francine Maria de Almeida, Iolanda de Fátima Lopes Calvo Tibério, Camila Uchoa Silva, Luan Henrique Alves Vasconcelos, Victoria Cristina Rodrigues de Souza, Alex Ferreira da Silva, Vitória Bernardino da Silva, Thaise Yumie Tomokane, Fernanda Degobbi Tenorio Quirino Santos Lopes, Aristides Tadeu Correia, Alyne Riani Moreira, Maria Rafaella Guedes Gomes   +15 more
core   +1 more source