Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death [PDF]
, 2015 Nanosized vesicles are considered key players in cell to cell communication, thus influencing physiological and pathological processes, including cancer.
Alessandro, R. +11 more
core +2 more sources
Genome-wide inhibition of pro-atherogenic gene expression by multi-STAT targeting compounds as a novel treatment strategy of CVDs [PDF]
, 2018 Cardiovascular diseases (CVDs), including atherosclerosis, are globally the leading cause of death. Key factors contributing to onset and progression of atherosclerosis include the pro-inflammatory cytokines Interferon (IFN)a and IFN?
Bluyssen, Hans A.R. +9 more
core +3 more sources
Tumor Biology, 2017 Considerable attention has been paid to the introduction of novel naturally occurring plant-derived radiosensitizer compounds in order to augment the radiation efficacy and improve the treatment outcome of different tumors.
Amina M Medhat +4 more
doaj +1 more source
Towards targeting overactive BMP signaling in Fibrodysplasia Ossificans Progressiva [PDF]
, 2015 Fibrodysplasia Ossificans Progressiva (FOP) is a rare monogenetic disorder in which patients develop heterotopic ossification (HO). A heterozygous mutation in BMP type I receptor ALK2 results in hyper-sensitized BMP signaling. The aim of this study is to
Sánchez-Duffhues, Gonzalo +2 more
core +2 more sources
Terpenes and Flavonoids From Salvia apiana and Their Affinities to Cannabinoid and Opioid Receptors [PDF]
, 2016 Salvia apiana (white sage, Lamiacae family) plant is native to southern California and parts of Mexico. Some Native American tribes local to this region consider S. apiana to be sacred and burn the leaves as incense for purification ceremonies. The plant
Hayes, Taylor
core +1 more source
인간 구강암 세포주에서 STAT3–Mcl-1 신호기전을 표적하는 TW-37의 세포자멸 및 상승 작용에 관한 연구 [PDF]
, 2021 학위논문(박사) -- 서울대학교대학원 : 치과대학 치의과학과, 2021.8. 조성대.Background: Despite being one of the leading cancer types in the world, the diagnosis of oral cancer and its suitable therapeutic options remain limited.
홍승현
core
Targeting SHP-1,2 and SHIP pathways – a novel strategy for cancer treatment? [PDF]
, 2018 Well balanced levels of tyrosine phosphorylation, maintained by the reversible and coordinated actions of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs), are critical for a wide range of cellular processes including growth ...
Chevassut, T +3 more
core +1 more source
Cancer Phytotherapy: Recent Views on the Role of Antioxidant and Angiogenesis Activities [PDF]
, 2017 Nowadays, increases in resistance of tumors to the current therapeutic agents have become a problematic issue. Therefore, efforts to discover new anticancer compounds with high sensitivity of cancer cells are extending.
Bahmani, Mahmoud. +4 more
core
Drug Design, Development and Therapy, 2017 Fayong Ke,1,2,* Zheng Wang,1,2,* Xiaoling Song,1,2 Qiang Ma,1,2 Yunping Hu,2 Lin Jiang,2 Yijian Zhang,2 Yingbin Liu,1,2 Yong Zhang,1 Wei Gong1,2 1Department of General Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai,
Ke FY +9 more
doaj
Effect of Harvest Time on Growth and Bioactive Compounds in Salvia miltiorrhiza
PlantsDanshen (Salvia miltiorrhiza) is a perennial medicinal plant belonging to the Lamiaceae family. It is adapted to a wide range of soil pH with the potential to serve as an alternative crop in the United States.
Zhiheng Xing +4 more
doaj +1 more source