Results 1 to 10 of about 16,703 (172)

Salvianolic acid B: a promising cardioprotective agent. [PDF]

Front Immunol
Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma] is a core herb in traditional Chinese medicine widely used for treating cardiovascular diseases (CVD). Its key bioactive compound, salvianolic acid B (SalB), has emerged as a promising therapeutic agent for CVD.
Shao Y, Zhai L, Jiang S, Sun F, Liu X.
europepmc   +5 more sources

Pharmacological Effects of Salvianolic Acid B Against Oxidative Damage [PDF]

Frontiers in Pharmacology, 2020
Salvianolic acid B (Sal B) is one of the main active ingredients of Salvia miltiorrhiza, with strong antioxidant effects. Recent findings have shown that Sal B has anti-inflammatory, anti-apoptotic, anti-fibrotic effects and can promote stem cell proliferation and differentiation, and has a beneficial effect on cardiovascular and cerebrovascular ...
Xiao-Ning Wang, Jiamei Chen, Ping Liu
exaly   +5 more sources

Salvianolic acid B in fibrosis treatment: a comprehensive review. [PDF]

Front Pharmacol
Fibrosis is a public health issue of great concern characterized by the excessive deposition of extracellular matrix, leading to the destruction of parenchymal tissue and organ dysfunction that places a heavy burden on the global healthcare system due to its high incidence, disability, and mortality.
Liang Q, Liu X, Peng X, Luo T, Su Y, Xu X, Xie H, Gao H, Chen Z, Xie C.   +9 more
europepmc   +5 more sources

Inhibition of Tanshinone IIA, Salvianolic Acid A and Salvianolic Acid B on Areca Nut Extract-Induced Oral Submucous Fibrosis in Vitro [PDF]

Molecules, 2015
Salvia miltiorrhiza Bunge has been reported to possess excellent antifibrotic activity. In this study, we have investigated the effect and mechanism of tanshinone IIA (Tan-IIA), salvianolic acid A (Sal-A) and salvianolic acid B (Sal-B), the important active compounds of Salvia miltiorrhiza Bunge, on areca nut extract (ANE)-induced oral submucous ...
Yun Su, Jian-Ping Dai
exaly   +4 more sources

Possible applications of salvianolic acid B against different cancers [PDF]

Exploration of Targeted Anti-tumor Therapy, 2020
Cancer is the second death causing disease worldwide after cardiovascular abnormalities. The difficulty in treating tumor cells with more precise targeted interventions and recurrence of cancer after treatment may pose great difficulty in developing sustainable therapeutic regimens.
Iram Shahzadi, Zain Ali, Sidra Bukhari, Acharan S Narula, Bushra Mirza, Reza Mohammadinejad   +5 more
openaire   +4 more sources

Effects of salvianolic acid A and salvianolic acid B in renal interstitial fibrosis via PDGF-C/PDGFR-α signaling pathway

Phytomedicine, 2022
Renal interstitial fibrosis (RIF) is the main pathological feature of end-stage renal disease (ESRD) caused by various chronic kidney diseases (CKD), and is closely related to renal dysfunction and patient prognosis. Salvianolic acid A (Sal A) and salvianolic acid B (Sal B), isolated from traditional Chinese medicine Salviae miltiorrhizae, have been ...
Yingjin Qiao
exaly   +3 more sources

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases. [PDF]

Front Pharmacol
BackgroundNeurological diseases such as stroke and Alzheimer’s disease pose increasing challenges to global public health. Salvianolic Acid B (SalB), a major active component of Salvia miltiorrhiza, has garnered attention due to its anti-inflammatory, antioxidant, neuroprotective, and pro-angiogenic properties in neurological disease treatment ...
Bi S, Liu S, Zhu K, Gao D, Chen L, Yu C, Liang G.   +6 more
europepmc   +4 more sources

Cardiovascular Effects of Salvianolic Acid B [PDF]

Evidence-Based Complementary and Alternative Medicine, 2013
Salvianolic acid B (SAB, Sal B) is the representative component of phenolic acids derived from the dried root and rhizome ofSalvia miltiorrhizaBge (Labiatae) which has been used widely and successfully in Asian countries for clinical therapy of various vascular disturbance-related diseases for hundreds of years.
Wang, Jie, Xiong, Xingjiang, Feng, Bo
openaire   +3 more sources

Current Progress of Research on Neurodegenerative Diseases of Salvianolic Acid B [PDF]

Oxidative Medicine and Cellular Longevity, 2019
Salvia miltiorrhizaBunge (Lamiaceae), one of the most commonly used traditional Chinese herbs, is widely used for the treatment of cardiovascular disease, cerebrovascular disease, Alzheimer’s disease, and Parkinson’s disease in clinical practice. Salvianolic acid B (Sal B, C36H30O16,FW=718.62) is the main water-soluble active ingredient ofSalvia ...
Rui Zhao, Xifang Liu, Lixin Zhang, Hao Yang, Qian Zhang   +4 more
openaire   +3 more sources

Alleviatory Effects of Danshen, Salvianolic Acid A and Salvianolic Acid B on Pc12 Neuronal Cells and Drosophila Melanogaster Model of Alzheimer’s Disease [PDF]

Journal of Ethnopharmacology, 2020
Abstract Background: Alzheimer’s disease (AD) is the most common form of neurodegenerative disorder worldwide. Its pathogenesis involves the hallmark aggregation of amyloid-beta (Aβ). Of all the Aβ oligomers formed in the brain, Aβ42 has been found to be the most toxic and aggressive.
Florence Hui Ping Tan, Andrew Chung Jie Ting, Ban Guan Leow, Nazalan Najimudin, Nobumoto Watanabe, Ghows Azzam   +5 more
openaire   +2 more sources