Results 1 to 10 of about 17,371 (133)

Hierarchical Au–Pt Nanostructured Film-Enabled Electrochemical Sensor for Highly-Sensitive Determination of Salvianolic Acid B [PDF]

Biosensors
Salvianolic acid B is an important bioactive biomarker in traditional Chinese medicines (TCMs). Current methods for its quantitation are time- and cost-consuming; a rapid and reliable method is urgently needed.
Yujiao Hou, Fang Lin, Xiang Gao, Jianhua Yang, Longfei Sun, Weijun Kong   +5 more
doaj   +2 more sources

Plant-Derived Polyphenol Salvianolic Acid B Attenuates Cardiomyocyte Pyroptosis by Modulating the MMP12-NLRP3 Signaling Axis. [PDF]

Food Sci Nutr
HG induces MMP12 upregulation in AC16 cardiomyocytes, which activates the NLRP3 inflammasome, triggers GSDMD‐mediated pyroptosis, and promotes the release of inflammatory cytokines. Sal B alleviates cardiomyocyte damage by modulating MMP12, while MMP12 overexpression abrogates this protective effect.
Xie Z, Yang ZK, Zheng L, Wu P, Chen S, Ye X, Gao Y.   +6 more
europepmc   +2 more sources

Salvianolic Acid B: A Review of Pharmacological Effects, Safety, Combination Therapy, New Dosage Forms, and Novel Drug Delivery Routes

Pharmaceutics, 2023
Salvianolic acid B is extracted from the roots and rhizomes of Danshen (Salvia miltiorrhiza Bge., family Labiatae). It is a water-soluble, weakly acidic drug that has demonstrated antitumor and anti-inflammatory effects on various organs and tissues such
Guannan He, Guangfeng Chen, Weidong Liu, Dongxue Ye, Xuehuan Liu, Xiaodong Liang, Jing Song   +6 more
doaj   +3 more sources

Salvianolic acid B: a promising cardioprotective agent [PDF]

Frontiers in Immunology
Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma] is a core herb in traditional Chinese medicine widely used for treating cardiovascular diseases (CVD).
Yingchun Shao, Li Zhai, Shan Jiang, Fusheng Sun, Xuedong Liu   +4 more
doaj   +2 more sources

M. canadensis and its active component salvianolic acid B overcome paclitaxel resistance in gastric cancer via ROS–ER stress signaling [PDF]

Cancer Cell International
Background Paclitaxel (PTX) is widely used for gastric cancer treatment; however, PTX resistance (PTXR) significantly limits clinical efficacy. Purpose To investigate the potential of Mentha canadensis and its bioactive component, salvianolic acid B, to ...
Bo Ram Kim, Heerim Yeo, Sang-Min Park, Seol Jang, Hye Mi Yun, Youn-Hwan Hwang, Sun Il Lee, Sang Cheul Oh, Han Na Kang   +8 more
doaj   +2 more sources

Ultrasonic-assisted nanofiltration separation recovering salvianolic acid B from ethanol wastewater [PDF]

Ultrasonics Sonochemistry
The transformation of salvianolic acid B brought on by heat treatment recovery of ethanol eluent, which is a difficult problem in pharmaceutical technology, affects the purity of raw material when the medicinal raw material salvianolic acid B is purified
Cunyu Li, Yun Ma, Yangyang Xu, Ranyun Qiu, Xin Shen, Lulu Huang, Anrong Liu, Mingming Li, Yunfeng Zheng, Xinglei Zhi   +9 more
doaj   +2 more sources

Ginsenoside Rb1, salvianolic acid B and their combination modulate gut microbiota and improve glucolipid metabolism in high-fat diet induced obese mice [PDF]

PeerJ, 2021
Background To observe the effect of ginsenoside Rb1, salvianolic acid B and their combination on glucolipid metabolism and structural changes of gut microbiota. Methods Eight-week-old C57BL/6J mice were fed 45% high-fat diet to induce obesity.
Ying Bai, Xueli Bao, Qianqian Mu, Xin Fang, Ruyuan Zhu, Chenyue Liu, Fangfang Mo, Dongwei Zhang, Guangjian Jiang, Ping Li, Sihua Gao, Dandan Zhao   +11 more
doaj   +2 more sources

Neuroprotective Effects of Geopung-Chunghyuldan Based on Its Salvianolic Acid B Content Using an In Vivo Stroke Model

Current Issues in Molecular Biology, 2023
Background: Geopung-Chunghyuldan (GCD) has neuroprotective properties. Salviae miltiorrhizae Radix plays an essential role in GCD’s effect. The Salviae miltiorrhizae Radix marker compound is salvianolic acid B; however, its content is not uniform among ...
Han-Gyul Lee, Seungwon Kwon, Sang-Kwan Moon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Jung-Mi Park, Chang-Nam Ko, Ki-Ho Cho   +8 more
doaj   +1 more source

Salvianolic acid B alleviates cartilage tissue damage in rat models with osteoarthritis [PDF]

Jichu yixue yu linchuang, 2023
Objective To explore whether salvianolic acid B affects cartilage tissue damage, hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF) in osteoarthritis rats. Methods A rat model of osteoarthritis was constructed, and rats were
QIAN Ligang, SUN Bo, YU Bo, CHEN Kang, MA Zheng, CHEN Taoping, WANG Yunfei
doaj   +1 more source

Salvianolic acid-B improves fat graft survival by promoting proliferation and adipogenesis

Stem Cell Research & Therapy, 2021
Background Our previous study proved that Salvia miltiorrhiza could enhance fat graft survival by promoting adipogenesis. However, the effect of salvianolic acid B (Sal-B), the most abundant and bioactive water-soluble compound in Salvia miltiorrhiza, on
Jia-Ming Sun, Chia-Kang Ho, Ya Gao, Chio-Hou Chong, Dan-Ning Zheng, Yi-Fan Zhang, Li Yu   +6 more
doaj   +1 more source