Results 1 to 10 of about 667,703 (231)

Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis. [PDF]

Redox Biol
Hepatocyte ferroptosis promotes the pathogenesis and progression of liver fibrosis. Salvianolic acid B (Sal B) exerts antifibrotic effects. However, the pharmacological mechanism and target has not yet been fully elucidated. In this study, liver fibrosis
Fu Y, Zhou X, Wang L, Fan W, Gao S, Zhang D, Ling Z, Zhang Y, Ma L, Bai F, Chen J, Sun B, Liu P.   +12 more
europepmc   +2 more sources

Salvianolic acid B inhibits thrombosis and directly blocks the thrombin catalytic site. [PDF]

Res Pract Thromb Haemost
Background Salvianolic acid B (SAB) is a major component of Salvia miltiorrhiza root (Danshen), widely used in East/Southeast Asia for centuries to treat cardiovascular diseases.
Neves MAD, Ni TT, Mackeigan DT, Shoara AA, Lei X, Slavkovic S, Yu SY, Stratton TW, Gallant RC, Zhang D, Xu XR, Fernandes C, Zhu G, Hu X, Chazot N, Donaldson LW, Johnson PE, Connelly K, Rand M, Wang Y, Ni H.   +20 more
europepmc   +2 more sources

Salvianolic Acid B-Loaded Chitosan/hydroxyapatite Scaffolds Promotes The Repair Of Segmental Bone Defect By Angiogenesis And Osteogenesis

International Journal of Nanomedicine, 2019
Chuanlei Ji,* Long Bi,* Jing Li, Junjun Fan Department of Orthopedics Surgery, Xijing Hospital, Air Force Medical University, Xi’an 710032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Li ...
Ji C, Long Bi, Junfa Li, Fan,Junjun
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Exploring the Mechanism of Salvianolic Acid B against Myocardial Ischemia-Reperfusion Injury Based on Network Pharmacology. [PDF]

Pharmaceuticals (Basel)
This study aimed to explore the mechanisms through which salvianolic acid B (Sal-B) exerts its effects during myocardial ischemia-reperfusion injury (MI/RI), aiming to demonstrate the potential pharmacological characteristics of Sal-B in the management ...
Mao Q, Shao C, Zhou H, Yu L, Bao Y, Zhao Y, Yang J, Wan H.   +7 more
europepmc   +2 more sources

A mussel-inspired, antibacterial, antioxidant, injectable composite hydrogel for the sustain delivery of salvianolic acid B for the treatment of frozen shoulder. [PDF]

Bioact Mater
Frozen shoulder (FS) manifests as progressively worsening pain and a reduction in shoulder range of motion (ROM). Salvianolic acid B (SaB) is recently expected to be used in the treatment of fibrosis diseases including FS. We firstly demonstrate that SaB
Yan Y, Li X, Chen C, Cui D, Wang Z, Li M, Long Y, Zhang J, Li C, Wang Z, Zhou C, Yao Z, Wang D, Hou J, Yang R.   +14 more
europepmc   +2 more sources

SALVIANOLIC ACID B FOR PULMONARY DELIVERY TOWARDS REVERSAL OF EMPHYSEMA

, 2017
VCU Theses and ...
Sneha Dhapare
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Differential Proteomic Analysis of Platelets Suggested Possible Signal Cascades Network in Platelets Treated with Salvianolic Acid B

, 2011
Chao Ma, Yan Yao, Qing‐Xi Yue, Xinwen Zhou, Pengyuan Yang, Wanying Wu, Shuhong Guan, Baohong Jiang, Min Yang, Xuan Liu, De‐an Guo   +10 more
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Salvianolic Acid B Significantly Suppresses the Migration of Melanoma Cells via Direct Interaction with β-Actin. [PDF]

Molecules
Zhang Y, Zhai W, Fan M, Wu J, Wang C.
europepmc   +1 more source

EXPRESSION OF CONCERN: Neuroprotective Mechanism of Salvianolic Acid B Against Cerebral Ischemia-Reperfusion Injury in Mice Through Downregulation of TLR4, p-p38MAPK, p-JNK, NF-κB, and IL-1β. [PDF]

Immun Inflamm Dis
europepmc   +1 more source