Results 21 to 30 of about 667,703 (231)

Safety, tolerance, and pharmacokinetics of salvianolic acid B in healthy Chinese volunteers: A randomized, double-blind, placebo-controlled phase 1 clinical trial

Frontiers in Pharmacology, 2023
Background: Salvianolic acid B (Sal B) is one of the main active ingredients of Salvia miltiorrhiza Bunge. In China, many traditional Chinese medicines have been modified into injections for higher bioavailability and better efficacy.
Jun-lin Cheng, Jun Long, Jingjing Zhang, Le-qiang Han, Yunfang Hu, Jianghui Liu, Runze Qiu, Zhibin Zhu, H. Fan   +8 more
semanticscholar   +3 more sources

Possible applications of salvianolic acid B against different cancers [PDF]

Exploration of Targeted Anti-tumor Therapy, 2020
Cancer is the second death causing disease worldwide after cardiovascular abnormalities. The difficulty in treating tumor cells with more precise targeted interventions and recurrence of cancer after treatment may pose great difficulty in developing sustainable therapeutic regimens.
Iram Shahzadi, Zain Ali, Sidra Bukhari, Acharan S Narula, Bushra Mirza, Reza Mohammadinejad   +5 more
openaire   +4 more sources

Experimental and theoretical assessment of salvianolic acid B, ellagic acid, and phorbol esters as drug candidates against breast and prostate cancer

Discover Chemistry
Global efforts to develop innovative anti-cancer lead compounds from natural compounds found in plants have gained advanced momentum, focusing on achieving Sustainable Development Goal (SDG) number 3 on good health and well-being.
R. B. Ouma, U. Raza, S. Ngari, J. Kibet, Uzair Nisar, Muhammad Waqar Ali   +5 more
semanticscholar   +2 more sources

Salvianolic acid B attenuates cellular senescence and age-related decline in muscle function via dual mTOR/TP53INP2-autophagy regulation. [PDF]

Front Chem
Liang K, Hu M, Zhao H, Xu W, Zhang Y, He R, Peng C, Chen H, Ju Z, Wu S, Ge Y.   +10 more
europepmc   +3 more sources

Alleviatory effects of Danshen, Salvianolic acid A and Salvianolic acid B on PC12 neuronal cells and Drosophila melanogaster model of Alzheimer’s disease [PDF]

Journal of Ethnopharmacology, 2020
Abstract Background: Alzheimer’s disease (AD) is the most common form of neurodegenerative disorder worldwide. Its pathogenesis involves the hallmark aggregation of amyloid-beta (Aβ). Of all the Aβ oligomers formed in the brain, Aβ42 has been found to be the most toxic and aggressive.
Florence Hui Ping Tan, Andrew Chung Jie Ting, Nazalan Najimudin, Nobumoto Watanabe, Ghows Azzam   +4 more
openalex   +4 more sources

Cardiovascular Effects of Salvianolic Acid B [PDF]

Evidence-Based Complementary and Alternative Medicine, 2013
Salvianolic acid B (SAB, Sal B) is the representative component of phenolic acids derived from the dried root and rhizome ofSalvia miltiorrhizaBge (Labiatae) which has been used widely and successfully in Asian countries for clinical therapy of various vascular disturbance-related diseases for hundreds of years.
Wang, Jie, Xiong, Xingjiang, Feng, Bo
openaire   +3 more sources

Ginsenoside Rb1, salvianolic acid B and their combination modulate gut microbiota and improve glucolipid metabolism in high-fat diet induced obese mice [PDF]

PeerJ, 2021
Background To observe the effect of ginsenoside Rb1, salvianolic acid B and their combination on glucolipid metabolism and structural changes of gut microbiota. Methods Eight-week-old C57BL/6J mice were fed 45% high-fat diet to induce obesity.
Ying Bai, Xueli Bao, Qianqian Mu, Xin Fang, Ruyuan Zhu, Chenyue Liu, Fangfang Mo, Dongwei Zhang, Guangjian Jiang, Ping Li, Sihua Gao, Dandan Zhao   +11 more
doaj   +2 more sources

[Retracted] Salvianolic acid B protects against sepsis-induced liver injury via activation of SIRT1/PGC-1α signaling. [PDF]

Exp Ther Med
Su H, Ma Z, Guo A, Wu H, Yang X.
europepmc   +3 more sources

The Chinese herb component salvianolic acid B induces copper-mediated reactive oxygen species generation and oxidative DNA damage. [PDF]

Genes Environ
Kobayashi H, Fukuhara K, Ohno A, Hirao Y, Katoh H, Mori Y, Kawanishi S, Murata M, Oikawa S.   +8 more
europepmc   +3 more sources

Protective effect of salvianolic acid B against myocardial ischemia/reperfusion injury: preclinical systematic evaluation and meta-analysis. [PDF]

Front Pharmacol
Yang Y, Sun Z, Sun X, Zhang J, Tong T, Zhang X, Yao K.   +6 more
europepmc   +3 more sources