Results 21 to 30 of about 16,703 (172)
Pharmaceutics, 2020 Psoriasis is a chronic inflammatory skin disorder with a pathogenesis involving the interleukin-23/interleukin-17 axis. Salvianolic acid B exerts several pharmacological effects, such as antioxidation, anti-inflammation, and antitumor effects.
Jiun-Wen Guo +7 more
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Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling
Annals of Hepatology, 2021 Introduction and objectives: The activation of hepatic stellate cells (HSCs) is the main cause of liver fibrosis. The beneficial effects of fibroblast growth factor (FGF) 19 on liver fibrosis were recently reported. The S.
Shuxia Tian +5 more
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Molecules, 2015 Salvianolic acid Y (TSL 1), a new phenolic acid with the same planar structure as salvianolic acid B, was isolated from Salvia officinalis. The structural elucidation and stereochemistry determination were achieved by spectroscopic and chemical methods ...
Jun Gong +13 more
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Frontiers in Pharmacology, 2023 Background: Salvianolic acid B (Sal B) is one of the main active ingredients of Salvia miltiorrhiza Bunge. In China, many traditional Chinese medicines have been modified into injections for higher bioavailability and better efficacy.
Junlin Cheng +8 more
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Salvianolic acid B protects the myelin sheath around injured spinal cord axons
Neural Regeneration Research, 2016 Salvianolic acid B, an active pharmaceutical compound present in Salvia miltiorrhiza, exerts a neuroprotective effect in animal models of brain and spinal cord injury.
Zhe Zhu +4 more
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Journal of Inflammation, 2012 The aim of this study was to investigate the hepatoprotective effect of Matrine salvianolic acid B salt on carbon tetrachloride (CCl4)-induced hepatic fibrosis in rats. Salvianolic acid B and Matrine has long been used to treat liver fibrosis.
Gao Hong-Ying +5 more
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Frontiers in Pharmacology, 2022 Phenolic acids are cardiovascular constituents (originating from the Chinese medicinal herb Salvia miltiorrhiza root/Danshen) of DanHong and many other Danshen-containing injections.
Jun-Lan Lu +23 more
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Synthesis of SMND-309, a derivate of salvianolic acid B
Synthetic Communications, 2017 (E)-2-(6-((E)-2-carboxyvinyl)-2,3-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl) acrylic acid, designated SMND-309, was synthesized starting from 2-hydroxy-3-methoxybenzaldehyde in 12 steps and with an overall yield of 44%. The synthetic key features were the conversion of aryl aldehyde into aryl acetic acid for one-carbon extended, the Perkin condensation ...
Wu, Kong +3 more
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Analysis on the Stability of Total Phenolic Acids and Salvianolic Acid B from by HPLC and HPLC-MS
Natural Product Communications, 2008 The stability of salvianolic acid B and total phenolic acids from Salvia miltiorrhiza in water solutions at different temperatures, in buffered aqueous solutions at different pHs and in biological fluids, including simulated gastric and intestinal fluids,
Man Xu +5 more
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Evaluation of Wound Healing Activity of Salvianolic Acid B on In Vitro Experimental Model [PDF]
International Journal of Molecular Sciences, 2021 Despite a wide range of bactericides and antiseptics, the treatment of chronic or complicated wounds is still a major challenge for modern medicine. Topical medications are the most sought-after new agents for use as treatment. The therapeutic concentration of their active substances is easy to achieve with the lowest possible burden on the patient’s ...
Urszula Szwedowicz +3 more
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