Results 21 to 30 of about 14,544,374 (201)

Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection [PDF]

Journal of Biomedical Science, 2011
Salvianolic acids are the most abundant water-soluble compounds extracted from Radix Salvia miltiorrhiza (Danshen). In China, Danshen has been wildly used to treat cardiovascular diseases for hundreds of years.
Ho Jennifer, Hong Chuang-Ye
doaj   +2 more sources

Salvianolic acid B inhibited high glucose-induced endothelial-mesenchymal transition through a down-regulation of β-catenin

Linchuang shenzangbing zazhi, 2021
Objective To explore the role of salvianolic acid B during phenotypic transition of endothelial cells induced by high glucose and elucidate the possible mechanism of β-catenin pathway.Methods Human umbilical vein endothelial cells were divided into 3 ...
Jing Ran, Li Ying-ying, Li Xiao-ping, Zhang Wan-fen, Feng Li-ping, Liu Tong-qiang   +5 more
doaj   +1 more source

Salvianolic acid B protects against myocardial damage caused by nanocarrier TiO2; and synergistic anti-breast carcinoma effect with curcumin via codelivery system of folic acid-targeted and polyethylene glycol-modified TiO2 nanoparticles

International Journal of Nanomedicine, 2016
Lingling Ding,1–3 Jiawei Li,1,2 Rui Huang,1,2 Zhidong Liu,1,2 Chunhua Li,1–3 Shaozi Yao,1,2 Jinyan Wang,1,2 Dongli Qi,1,2 Nan Li,1,2 Jiaxin Pi1,21Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese ...
Ding L, Li J, Huang R, Liu Z, Li C, Yao S, Wang J, Qi D, Li N, Pi J   +9 more
doaj   +1 more source

Cardiovascular Effects of Salvianolic Acid B [PDF]

Evidence-Based Complementary and Alternative Medicine, 2013
Salvianolic acid B (SAB, Sal B) is the representative component of phenolic acids derived from the dried root and rhizome ofSalvia miltiorrhizaBge (Labiatae) which has been used widely and successfully in Asian countries for clinical therapy of various vascular disturbance-related diseases for hundreds of years.
Wang, Jie, Xiong, Xingjiang, Feng, Bo
openaire   +3 more sources

Possible applications of salvianolic acid B against different cancers [PDF]

Exploration of Targeted Anti-tumor Therapy, 2020
Cancer is the second death causing disease worldwide after cardiovascular abnormalities. The difficulty in treating tumor cells with more precise targeted interventions and recurrence of cancer after treatment may pose great difficulty in developing sustainable therapeutic regimens.
Iram Shahzadi, Zain Ali, Sidra Bukhari, Acharan S Narula, Bushra Mirza, Reza Mohammadinejad   +5 more
openaire   +3 more sources

Inhibitory Effect of Salvia miltiorrhiza Extract and Its Active Components on Cervical Intraepithelial Neoplastic Cells

Molecules, 2022
The effective treatment of cervical intraepithelial neoplasia (CIN) can prevent cervical cancer. Salvia miltiorrhiza is a medicinal and health-promoting plant. To identify a potential treatment for CIN, the effect of S.
Xuejiao Leng, Hongfei Kan, Qinhang Wu, Cunyu Li, Yunfeng Zheng, Guoping Peng   +5 more
doaj   +1 more source

Alleviatory Effects of Danshen, Salvianolic Acid A and Salvianolic Acid B on Pc12 Neuronal Cells and Drosophila Melanogaster Model of Alzheimer’s Disease [PDF]

Journal of Ethnopharmacology, 2020
Abstract Background: Alzheimer’s disease (AD) is the most common form of neurodegenerative disorder worldwide. Its pathogenesis involves the hallmark aggregation of amyloid-beta (Aβ). Of all the Aβ oligomers formed in the brain, Aβ42 has been found to be the most toxic and aggressive.
Florence Hui Ping Tan, Andrew Chung Jie Ting, Ban Guan Leow, Nazalan Najimudin, Nobumoto Watanabe, Ghows Azzam   +5 more
openaire   +2 more sources

Salvianolic acid B attenuates renal interstitial fibrosis in rats with unilateral ureteral obstruction via Nrf2-Gpx4 pathway-mediated ferroptosis

Di-san junyi daxue xuebao, 2022
Objective To determine the improving effect of salvianolic acid B on renal interstitial fibrosis (RIF) of rats with unilateral ureteral obstruction (UUO) based on ferroptosis mediated by nuclear factor erythroid 2-related factor 2 (Nrf2)-glutathione ...
SUN Yuanbo, SONG Yanran, WANG Shiqi, SUN Lixin, LI Guiqin   +4 more
doaj   +1 more source

Current Progress of Research on Neurodegenerative Diseases of Salvianolic Acid B [PDF]

Oxidative Medicine and Cellular Longevity, 2019
Salvia miltiorrhizaBunge (Lamiaceae), one of the most commonly used traditional Chinese herbs, is widely used for the treatment of cardiovascular disease, cerebrovascular disease, Alzheimer’s disease, and Parkinson’s disease in clinical practice. Salvianolic acid B (Sal B, C36H30O16,FW=718.62) is the main water-soluble active ingredient ofSalvia ...
Rui Zhao, Xifang Liu, Lixin Zhang, Hao Yang, Qian Zhang   +4 more
openaire   +2 more sources

Salvianolic acid B in fibrosis treatment: a comprehensive review. [PDF]

Front Pharmacol
Fibrosis is a public health issue of great concern characterized by the excessive deposition of extracellular matrix, leading to the destruction of parenchymal tissue and organ dysfunction that places a heavy burden on the global healthcare system due to its high incidence, disability, and mortality.
Liang Q, Liu X, Peng X, Luo T, Su Y, Xu X, Xie H, Gao H, Chen Z, Xie C.   +9 more
europepmc   +4 more sources