Results 31 to 40 of about 667,703 (231)

Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling

Annals of Hepatology, 2020
Introduction and objectives: The activation of hepatic stellate cells (HSCs) is the main cause of liver fibrosis. The beneficial effects of fibroblast growth factor (FGF) 19 on liver fibrosis were recently reported. The S.
Shuxia Tian, Min Chen, Bing Wang, Yonglong Han, Haonan Shang, Junming Chen   +5 more
openalex   +3 more sources

M. canadensis and its active component salvianolic acid B overcome paclitaxel resistance in gastric cancer via ROS-ER stress signaling. [PDF]

Cancer Cell Int
Background Paclitaxel (PTX) is widely used for gastric cancer treatment; however, PTX resistance (PTXR) significantly limits clinical efficacy. Purpose To investigate the potential of Mentha canadensis and its bioactive component, salvianolic acid B, to ...
Kim BR, Yeo H, Park SM, Jang S, Yun HM, Hwang YH, Lee SI, Oh SC, Kang HN.   +8 more
europepmc   +2 more sources

The role of salvianolic acid B and benzoylpaeoniflorin in enhancing angiogenesis through Nrf2/HO-1/VEGFA signaling axis in ischemic stroke recovery. [PDF]

Pharm Biol
Zhao C, Bai X, Ding Y, Zeng A, Wen A, Fu Q, Wang J.   +6 more
europepmc   +3 more sources

Role of salvianolic acid B in the treatment of acute ischemic stroke: a systematic review and meta-analysis of animal models. [PDF]

Front Pharmacol
Wang J, Su P, Wan C, Xu Y, Huang J, Niu J, Jin Z.   +6 more
europepmc   +3 more sources

Salvianolic Acid B Inhibits Oxidative Stress in Glomerular Mesangial Cells Alleviating Diabetic Nephropathy by Regulating SIRT3/FOXO1 Signaling

Kidney & Blood Pressure Research, 2023
Introduction: Oxidative stress is pivotal in advancing diabetic nephropathy (DN). Salvianolic acid B (SAB), derived from Radix Salviae miltiorrhizae, exhibits renoprotective effects.
Feiying Wen, Shengmiao Zhang, Liqin Sun, Manqing Qian, Haofeng Xu   +4 more
openalex   +2 more sources

Neuroprotective Effects of Geopung-Chunghyuldan Based on Its Salvianolic Acid B Content Using an In Vivo Stroke Model

Current Issues in Molecular Biology, 2023
Background: Geopung-Chunghyuldan (GCD) has neuroprotective properties. Salviae miltiorrhizae Radix plays an essential role in GCD’s effect. The Salviae miltiorrhizae Radix marker compound is salvianolic acid B; however, its content is not uniform among ...
Han-Gyul Lee, Seungwon Kwon, Sang-Kwan Moon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Jung-Mi Park, Chang-Nam Ko, Ki-Ho Cho   +8 more
doaj   +1 more source

Salvianolic acid B alleviates cartilage tissue damage in rat models with osteoarthritis [PDF]

Jichu yixue yu linchuang, 2023
Objective To explore whether salvianolic acid B affects cartilage tissue damage, hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF) in osteoarthritis rats. Methods A rat model of osteoarthritis was constructed, and rats were
QIAN Ligang, SUN Bo, YU Bo, CHEN Kang, MA Zheng, CHEN Taoping, WANG Yunfei
doaj   +1 more source

Salvianolic Acid B Attenuates Ferroptosis in Acute Kidney Injury by Targeting PRDX5. [PDF]

FASEB J
Acute kidney injury (AKI) is a common side effect of the chemotherapy agent cisplatin, and ferroptosis serves as the primary mechanism underlying cell death in renal tubular epithelium in such cases.
Tao Y, Fu S, Lu J, Fu B, Liu S, Li L.
europepmc   +2 more sources

Salvianolic Acid B Alleviates High Glucose-Induced Vascular Smooth Muscle Cell Inflammation by Upregulating the miR-486a-5p Expression. [PDF]

Mediators Inflamm
Zhang ML, Zhang MN, Chen H, Wang X, Zhao K, Li X, Song X, Tong F.   +7 more
europepmc   +3 more sources

Current Progress of Research on Neurodegenerative Diseases of Salvianolic Acid B [PDF]

Oxidative Medicine and Cellular Longevity, 2019
Salvia miltiorrhizaBunge (Lamiaceae), one of the most commonly used traditional Chinese herbs, is widely used for the treatment of cardiovascular disease, cerebrovascular disease, Alzheimer’s disease, and Parkinson’s disease in clinical practice. Salvianolic acid B (Sal B, C36H30O16,FW=718.62) is the main water-soluble active ingredient ofSalvia ...
Rui Zhao, Xifang Liu, Lixin Zhang, Hao Yang, Qian Zhang   +4 more
openaire   +3 more sources