Results 51 to 60 of about 14,544,374 (201)

Structure of Salvianolic acid B and Tanshinol.

, 2012
Salvianolic acid B consists of three molecules of Tanshinol (D (+) β-3,4-dihydroxyphenyl lactic acid, danshensu) and a molecule of caffeic acid.
Yan Chen (4308), Liao Cui (173191), Ting Li (117885), Lianfang Huang (173207), Tie Wu (173219), Yuyu Liu (173195), Bilian Xu (173204), Yanzhi Liu (173211), Webster S. S. Jee (173217), Xiaoyan Tian (173214), Le Zhou (173199), Pinghua Li (173201)   +11 more
core   +1 more source

Rosmarinic Acid Derivatives’ Inhibition of Glycogen Synthase Kinase-3β Is the Pharmacological Basis of Kangen-Karyu in Alzheimer’s Disease

Molecules, 2018
Inhibition of glycogen synthase kinase 3β (GSK-3β) is considered to be the central therapeutic approach against Alzheimer’s disease (AD).
Pradeep Paudel, Su Hui Seong, Yajuan Zhou, Chan Hum Park, Takako Yokozawa, Hyun Ah Jung, Jae Sue Choi   +6 more
doaj   +1 more source

Salvianolic Acid a Disrupts the HSP90α‐AKT‐PERK Ternary Complex to Alleviate Atherosclerosis by Activating Endoplasmic Reticulum Stress of Senescent Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Salvianolic acid A (SAA) selectively induces senescent vascular smooth muscle cell apoptosis, alleviating atherosclerosis. Mechanistically, SAA targets heat shock protein 90 alpha (HSP90α) to disrupt the protein inase B (AKT)‐PRKR‐Like Endoplasmic Reticulum Kinase (PERK) scaffold, driving ubiquitin‐proteasome‐dependent AKT degradation.
Xiuya Guan, Mengkai Lu, Xinhai Cui, Dawei Zhang, Lei Zhang, Lin Lin, Yuan Li, Yuanlong Hu, Chao Li   +8 more
wiley   +1 more source

Biocontrol and plant growth‐promoting potential of Streptomyces strains against fungal pathogens of tomato and wheat for a sustainable agriculture

Pest Management Science, EarlyView.
This study highlights the biocontrol potential of Streptomyces strain Strep_22. In vitro, it inhibits key fungal pathogens by 91.52%. In vivo, it significantly reduces disease incidence in wheat and tomato while enhancing biomass, shoot, and root development, offering a highly promising, sustainable ecological alternative to chemical pesticides ...
Thomas Conte, Maria Grazia Morea, Gaetana Ricciardi, Angelo Pastino, Francesco Lops, Maria Luisa Raimondo, Antonia Carlucci   +6 more
wiley   +1 more source

Molecular structures of salvianolic acid B (A) and rosmarinic acid (B).

, 2015
Molecular structures of salvianolic acid B (A) and rosmarinic acid (B).
Zhimin He (12076), Rongxin Su (720272), Renliang Huang (720271), Wei Qi (132539), Xin Peng (720270)   +4 more
core   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Metabolomic profiles of myocardial ischemia under treatment with salvianolic acid B [PDF]

Chinese Medicine, 2012
Abstract Background Radix Salvia miltiorrhiza (Danshen) has been used as a principal herb in treating cardiovascular diseases in Chinese medicine. Salvianolic acid B (SA-B), a water-soluble active component of Danshen, was found to have anti-myocardial ischemia (anti-MI) effect.
Lu, Y, Zheng, Y, Liu, X, Liang, X, Ngai, S, Li, T, Zhang, W   +6 more
openaire   +3 more sources

Chemical structures of salvianolic acid B, rosmarinic acid and caffeic acid.

, 2013
Chemical structures of salvianolic acid B, rosmarinic acid and caffeic acid.
Dongfeng Yang (185887), Yini Ma (452709), Tao Xu (3537), Yan Liu (25061), Zhixin Guo (452711), Beimi Cui (452710), Zongsuo Liang (185893)   +6 more
core   +1 more source

Cloning and characterization of a putative R2R3 MYB transcriptional repressor of the rosmarinic acid biosynthetic pathway from Salvia miltiorrhiza.

PLoS ONE, 2013
Salvia miltiorrhiza Bunge is one of the most renowned traditional medicinal plants in China. Phenolic acids that are derived from the rosmarinic acid pathway, such as rosmarinic acid and salvianolic acid B, are important bioactive components in S ...
Shuncang Zhang, Pengda Ma, Dongfeng Yang, Wenjing Li, Zongsuo Liang, Yan Liu, Fenghua Liu   +6 more
doaj   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source