Results 51 to 60 of about 16,703 (172)

Supramolecular Coordination Platforms for Smart Theranostics: Leveraging the Dynamic Molecular Networks of Metal–Polyphenol Assemblies

Aggregate, Volume 7, Issue 7, July 2026.
In this review, we summarize the recent developments of metal–polyphenol networks (MPNs) as a highly versatile and functionally integrated supramolecular assembly platform. We also discuss their pivotal role in steering biomedical materials away from conventional single‐function designs and toward intelligent, unified diagnostic and therapeutic ...
Kang Zhu, Minjing Guo, Wenping Li, Xiaoyu Zhang, Ling Chen, Jibin Song   +5 more
wiley   +1 more source

Salvianolic acid B inhibited high glucose-induced endothelial-mesenchymal transition through a down-regulation of β-catenin

Linchuang shenzangbing zazhi, 2021
Objective To explore the role of salvianolic acid B during phenotypic transition of endothelial cells induced by high glucose and elucidate the possible mechanism of β-catenin pathway.Methods Human umbilical vein endothelial cells were divided into 3 ...
Jing Ran, Li Ying-ying, Li Xiao-ping, Zhang Wan-fen, Feng Li-ping, Liu Tong-qiang   +5 more
doaj  

Comprehensive Phenolic Profiling and Antioxidant Evaluation of Calyx, Rind, and Edible Tissues From Non‐Astringent Persimmons (Diospyros kaki)

Chemistry &Biodiversity, Volume 23, Issue 7, July 2026.
Tissue‐specific phenolic profiling of non‐astringent persimmons (Fuyu and Jiro) reveals substantial differences in phytochemical composition and antioxidant potential. Persimmon calyx exhibits the highest concentrations of bioactive compounds, highlighting its potential as a valuable by‐product for functional food and nutraceutical applications ...
Huiwen Wang, Muhammad Sajid Arshad, Ayesha Siddiqa, Malik Adil Nawaz, Hafiz A. R. Suleria   +4 more
wiley   +1 more source

Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin [PDF]

Scientific Reports, 2017
AbstractSalvianolic acid B is an antioxidative ingredient derived from Radix Salviae miltiorrhizae that has been widely used to treat liver diseases. However, the therapeutic mechanism underlying Salvianolic acid B has remained largely unknown. Our studies verified that Salvianolic acid B efficiently blocked mitochondrial deformation and dysfunction ...
Yunxia Liu, Yingying Hu, Qiukai E, Ji Zuo, Ling Yang, Wen Liu   +5 more
openaire   +2 more sources

From Green Extraction to Gut Bioaccessibility: Synergistic Potential of Ginkgo biloba, Astragalus membranaceus, and Salvia miltiorrhiza Phytochemicals for Functional Food Applications

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This study optimized green extraction of a synergistic tri‐herbal blend of Ginkgo biloba, Astragalus membranaceus, and Salvia miltiorrhiza. The 1:1:2 blend showed the highest TPC synergy, with probe ultrasound giving maximal phenolic recovery. The extract, rich in rosmarinic acid, chlorogenic acid, and catechin, exhibited antioxidant, antimicrobial ...
Mohamed Ibrahim Younis, Yahia Ibrahim Sallam, Khaled Fahmy Mahmoud, Rawaa H. Tlay, M. Ali Aboudzadeh, Tarek Gamal Abedelmaksoud   +5 more
wiley   +1 more source

Salvianolic acid B attenuates experimental skin fibrosis of systemic sclerosis

Biomedicine & Pharmacotherapy, 2019
Systemic sclerosis (SSc) is a connective tissue disease characterized mainly by fibrosis of skin and internal organs. Our previous study has shown that salvianolic acid B (SAB), a bioactive component extracted from Salvia miltiorrhiza (SM), was one of the essential ingredients in the traditional Chinese medicine Yiqihuoxue formula, which has been used ...
Qingmei, Liu, Jiaying, Lu, Jinran, Lin, Yulong, Tang, Weilin, Pu, Xiangguang, Shi, Shuai, Jiang, Jing, Liu, Yanyun, Ma, Yuan, Li, Jinhua, Xu, Li, Jin, Jiucun, Wang, Wenyu, Wu   +13 more
openaire   +2 more sources

Salvianolic Acid B Upregulates miR‐744‐5p Expression in Peripheral Blood Mononuclear Cell–Derived Extracellular Vesicles to Alleviate Uremic Cardiomyopathy

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
Uremic cardiomyopathy (UCM) is a life‐threatening complication of uremia. We find that extracellular vesicle (EV)‐miR‐744‐5p mediates peripheral blood mononuclear cell (PBMC)‐cardiomyocyte communication in UCM. Salvianolic acid B treats UCM by modulating EV‐miR‐744‐5p expression.
Ziran Wang, Jiaojiao Hao, Yaxi Shang, Wenli Ma, Nan Wang, Weidong Wang, Qingzhu Tang, Xiangning Du, Fan Yang, Biaojie Qin, Shuni Chen, Kun Xiao, Longkai Li, Xianan Guo, Xin Qi, Shuang Meng, Huiyi Song, Hongli Lin   +17 more
wiley   +1 more source

Atherosclerosis: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Molecular factors, like transforming growth factor beta (TGF‐β), mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase (PI3K), or cyclin‐dependent kinases (CDKs) 5 and 9, are essential modulators of atherosclerotic lesions. The novel, promising strategies for atherosclerosis treatment include therapies based on small interfering RNA (siRNA)
Jonatan Kaszubski, Agata Wawrzyniak, Maciej Gagat, Agnieszka Żuryń   +3 more
wiley   +1 more source

Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity [PDF]

Phytomedicine, 2014
Salvianolic acid A (Sal A), an important constituent of Radix Salviae Miltiorrhizae (RSM), is effective for the treatment of myocardial infarction (MI) and coronary heart disease due to its potential in the improvement of acute myocardial ischemia. However, its content is very low in RSM.
Hongrui, Xia, Longru, Sun, Hongxiang, Lou, M Mukhlesur, Rahman   +3 more
openaire   +2 more sources

Natural Products as Modulators of ABC Transporters in Breast Cancer

Phytotherapy Research, Volume 40, Issue 7, Page 4611-4637, July 2026.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan, Reyhaneh Farghadani, Ammu K. Radhakrishnan   +2 more
wiley   +1 more source