Results 61 to 70 of about 667,703 (231)

Elucidating the influence of gold nanoparticles on the binding of salvianolic acid B and rosmarinic acid to bovine serum albumin.

PLoS ONE, 2015
Salvianolic acid B and rosmarinic acid are two main water-soluble active ingredients from Salvia miltiorrhiza with important pharmacological activities and clinical applications. The interactions between salvianolic acid B (or rosmarinic acid) and bovine
Xin Peng, Wei Qi, Renliang Huang, Rongxin Su, Zhimin He   +4 more
doaj   +1 more source

Effects of salvianolic acid B on liver fibrosis

Medicine, 2020
Abstract Background: Liver fibrosis is a pathological change existing in most chronic liver diseases, which leads to abnormal changes in liver tissue structure and affects the normal physiological function of liver. Without effectively control, liver fibrosis can develop into cirrhosis and increase the risk of liver ...
Xiaocong Ma, Meiwen Tang, Liying Lu, Jinghui Zheng, Jingjing Huang, Junhong Li, Weisheng Luo   +6 more
openaire   +2 more sources

Study on salvianolic acid B in the reduction of epidural fibrosis in laminectomy rats [PDF]

BMC Musculoskeletal Disorders, 2014
Epidural fibrosis (EF) is a common complication after laminectomy. Salvianolic acid B (Sal B) is a major bioactive component of a traditional Chinese medical agent, Salvia miltiorrhiza, which has shown anti-inflammatory, anti-fibrotic and anti-proliferative properties. The object of this study was to investigate the effect of Sal B on the prevention of
Chen, Feng, Zuo, Zhenbo, Wang, Kai, Zhang, Chengdong, Gong, Haifeng, Ye, Fagang, Ji, Aiyu, Tao, Hao   +7 more
openaire   +2 more sources

Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells

Bioengineered, 2022
Endothelial dysfunction is a critical mediator in the pathogenesis of vascular complications of diabetes. Herein, this study was conducted to investigate the therapeutic effects of Salvianolic acid B (Sal B) on diabetes-induced endothelial dysfunction ...
Jie Xiang, Chunling Zhang, Tietao Di, Lu Chen, Wei Zhao, Liang Wei, Shiyong Zhou, Xueli Wu, Gengxin Wang, Yun Zhang   +9 more
semanticscholar   +1 more source

Salvianolic acid B stimulates osteogenesis in dexamethasone-treated zebrafish larvae [PDF]

Acta Pharmacologica Sinica, 2016
Our previous studies show that salvianolic acid B (Sal B) promotes osteoblast differentiation and matrix mineralization. In this study, we evaluated the protective effects of Sal B on the osteogenesis in dexamethasone (Dex)-treated larval zebrafish, and elucidated the underlying mechanisms.At 3 d post fertilization, wild-type AB zebrafish larvae or ...
Shi-Ying, Luo, Jing-Feng, Chen, Zhi-Guo, Zhong, Xiao-Hua, Lv, Ya-Jun, Yang, Jing-Jing, Zhang, Liao, Cui   +6 more
openaire   +2 more sources

Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection

Journal of Biomedical Science, 2011
Salvianolic acids are the most abundant water-soluble compounds extracted from Radix Salvia miltiorrhiza (Danshen). In China, Danshen has been wildly used to treat cardiovascular diseases for hundreds of years.
Ho Jennifer, Hong Chuang-Ye
doaj   +1 more source

Injectable Hydrogels Based on Hyaluronic Acid and Gelatin Combined with Salvianolic Acid B and Vascular Endothelial Growth Factor for Treatment of Traumatic Brain Injury in Mice. [PDF]

Molecules
Traumatic brain injury (TBI) leads to structural damage in the brain, and is one of the major causes of disability and death in the world. Herein, we developed a composite injectable hydrogel (HA/Gel) composed of hyaluronic acid (HA) and gelatin (Gel ...
Zhou G, Cao Y, Yan Y, Xu H, Zhang X, Yan T, Wan H.   +6 more
europepmc   +2 more sources

Salvia miltiorrhiza in Breast Cancer Treatment: A Review of Its Phytochemistry, Derivatives, Nanoparticles, and Potential Mechanisms

Frontiers in Pharmacology, 2022
Breast cancer is one of the most deadly malignancies in women worldwide. Salvia miltiorrhiza, a perennial plant that belongs to the genus Salvia, has long been used in the management of cardiovascular and cerebrovascular diseases.
Huan Zhao, Bing Han, Xuan Li, Chengtao Sun, Yufei Zhai, Man Li, Mi Jiang, Weiping Zhang, Yi Liang, Guoyin Kai   +9 more
doaj   +1 more source

Salvianolic acid B inhibits autophagy and protects starving cardiac myocytes [PDF]

Acta Pharmacologica Sinica, 2010
To investigate the protective or lethal role of autophagy and the effects of Salvianolic acid B (Sal B) on autophagy in starving myocytes.Cardiac myocytes were incubated under starvation conditions (GD) for 0, 1, 2, 3, and 6 h. Autophagic flux in starving cells was measured via chloroquine (3 μmol/L).
Han, Xiao, Liu, Jianxun (R17789), Li, Xinzhi   +2 more
openaire   +3 more sources

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source