Results 61 to 70 of about 14,544,374 (201)

Contour plots of parameter interactions on Salvianolic acid B yield.

, 2015
Contour plots of parameter interactions on Salvianolic acid B yield.
Yao Li (154923), Huali Chen (2261914), Xingchu Gong (611198), Haibin Qu (611199)   +3 more
core   +1 more source

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases. [PDF]

Front Pharmacol
BackgroundNeurological diseases such as stroke and Alzheimer’s disease pose increasing challenges to global public health. Salvianolic Acid B (SalB), a major active component of Salvia miltiorrhiza, has garnered attention due to its anti-inflammatory, antioxidant, neuroprotective, and pro-angiogenic properties in neurological disease treatment ...
Bi S, Liu S, Zhu K, Gao D, Chen L, Yu C, Liang G.   +6 more
europepmc   +4 more sources

Salvianolic Acid C Protects Against Hepatic Ischemia–Reperfusion Injury via Heat Shock Protein 90α‐Mediated Activation of the Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling Pathway

Phytotherapy Research, EarlyView.
Salvianolic acid C (SaC) protects against hepatic ischemia–reperfusion injury (HIRI) by upregulating HSP90α and activating the PI3K/AKT pathway, thereby alleviating oxidative stress, inflammation, apoptosis, and necrosis. ABSTRACT Hepatic ischemia–reperfusion injury (HIRI) is a major challenge in liver surgery, and effective pharmacological ...
Pingping Qiao, Alimu Tulahong, Xinlu Xu, Tiemin Jiang, Ruiqing Zhang, Yanze Lin, Zhongdian Yuan, Rexiati Ruze, Yingmei Shao   +8 more
wiley   +1 more source

Fast Screening of Protein Tyrosine Phosphatase 1B Inhibitor from Salvia miltiorrhiza Bge by Cell Display-Based Ligand Fishing

Molecules, 2022
Salvia miltiorrhiza Bge is a medicinal plant (Chinese name “Danshen”) widely used for the treatment of hyperglycemia in traditional Chinese medicine.
Xiaolin Bai, Wenqin Fan, Yingjie Luo, Yipei Liu, Yongmei Zhang, Xun Liao   +5 more
doaj   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2

, 2018
Salvianolic acid B (SalB) is one of the most bioactive components extracted from Salvia miltiorrhiza, and its antioxidant capacity corresponds with its protective effects against cell injury from oxidative stress.
Liu, Lianqing, Ma, Enlong, Liu M(刘苗), Liu, Miao, Zhang, Cai, Li YC(李艳春), Xu, Hanying, Li, Yanchun, Liu LQ(刘连庆), Zhang, Ling, Yang, Liancheng   +10 more
core   +1 more source

EETs mediate cardioprotection of salvianolic acids through MAPK signaling pathway

Acta Pharmaceutica Sinica B, 2013
Salvianolic acids, including salvianolic acid A (SAA) and salvianolic acid B (SAB), are the main water-soluble bioactive compounds isolated from the Chinese medicinal herb Danshen and have been shown to exert in vitro and in vivo cardiovascular ...
Shoubao Wang, Weiku Zhang, Xiaobin Pang, Li Li, Guorong He, Xiuying Yang, Lianhua Fang, Juntian Zhang, Guanhua Du   +8 more
doaj   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Intervention Effect of Compatibility of Salvianolic Acid A & B on PDGF-C/PDGFR-α Signaling Pathway in Renal Fibrosis

, 2015
Objective: To explore the effect of salvianolic acid A & B component molecules of drug compatibility on PDGF-c/PDGFR-α signaling pathway in renal fibrosis of rats.
Yu, Bin
core   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source