Results 61 to 70 of about 16,703 (172)
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
SALVIANOLIC ACID B ALLEVIATING MYOCARDIUM INJURY IN ISCHEMIA REPERFUSION RATS.
Salvia miltiorrhiza (SM) Bunge is one of the widely-used Chinese medicinal herbs. Salvianolic acid B (Sal B), a bioactive compound isolated from the Chinese herb Radix Salviae Miltiorrhizae, has been reported to exhibit anti-inflammatory and anti-oxidantive effects.To study the cardioprotective effects of salvianolic acid B (Sal B) on acute myocardial ...
Qiao, Zengyong, Xu, Yawei
openaire +3 more sources
Correlation analysis based on chromatograms and pharmacological activities is essential for understanding the effective components in complex herbal medicines.
Shen Jie +3 more
doaj +1 more source
Traditional Respiratory Remedies From Anatolia: Ethnobotanical Insights and Bioactive Properties
ABSTRACT Respiratory disorders, ranging from acute viral infections such as influenza and bronchitis to chronic inflammatory conditions including chronic obstructive pulmonary disease, asthma, emphysema, and pneumonia, represent a major global health burden, affecting millions annually. Traditional Anatolian folk medicine has long relied on plant‐based
Golshan Zare +5 more
wiley +1 more source
Global efforts to develop innovative anti-cancer lead compounds from natural compounds found in plants have gained advanced momentum, focusing on achieving Sustainable Development Goal (SDG) number 3 on good health and well-being.
Russell B. O. Ouma +5 more
doaj +1 more source
The Supporting Role of Natural Products as Effective Adjuvants in Cancer Immunotherapy
Natural products, as multi‐target and low‐toxicity adjuvants, enhance immune checkpoint inhibitor responses and reduce immune‐related adverse events through T cell reprogramming, microenvironment remodeling, and microbiota‐immune modulation. ABSTRACT Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of malignant tumors ...
Boyang Liu +6 more
wiley +1 more source
Cardio-Protection of Salvianolic Acid B through Inhibition of Apoptosis Network
Targeting cellular function as a system rather than on the level of the single target significantly increases therapeutic potency. In the present study, we detect the target pathway of salvianolic acid B (SalB) in vivo. Acute myocardial infarction (AMI) was induced in rats followed by the treatment with 10 mg/kg SalB.
Lingling Xu +13 more
openaire +4 more sources
Chuanlei Ji,* Long Bi,* Jing Li, Junjun Fan Department of Orthopedics Surgery, Xijing Hospital, Air Force Medical University, Xi’an 710032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Li ...
Ji C, Bi L, Li J, Fan J
doaj
Salvianolic acid B decreases interleukin-1β-induced colitis recurrence in mice
. Background. Degree of mucosal recovery is an important indicator for evaluating the therapeutic effects of drugs in treatment of inflammatory bowel disease (IBD).
Pan-Pan Feng +9 more
doaj +1 more source
Encephalopathy: Cause, Pathogenesis, and Treatment
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv +7 more
wiley +1 more source

