Results 81 to 90 of about 19,334 (212)

The Role of Piezo 1 in the Study of Intervertebral Disc Degeneration: Phenotype, Mechanism and Treatment

open access: yesOrthopaedic Surgery, Volume 18, Issue 5, Page 897-914, May 2026.
As the key mechanotransducer in IVDD, Piezo1 orchestrates region‐specific degeneration across NP (senescence/ECM dysregulation), AF (apoptosis), and CEP (inflammation). This review integrates mechanistic pathways and assesses multimodal therapeutic targeting (pharmacologic/genetic/nutritional) to restore disc homeostasis.
Guangye Li   +5 more
wiley   +1 more source

Salvianolic acid B activates Wnt/β‑catenin signaling following spinal cord injury

open access: yesExperimental and Therapeutic Medicine, 2019
Neural cell apoptosis serves a key role in spinal cord injury (SCI), which is a threat to human health. The present study aimed to evaluate the neuroprotective mechanism of salvianolic acid B (Sal B) in a spinal cord injury (SCI) rat model. Basso, Beattie, and Bresnahan scores demonstrated that Sal B treatment significantly increased locomotor ...
Zhou, Hongming   +4 more
openaire   +3 more sources

Mycorrhizal fungi were more effective than zeolites in increasing the growth of non-irrigated young olive trees [PDF]

open access: yes, 2020
Four soil treatments, consisting of two commercial mycorrhizal fungi, one zeolite and an untreated control, were arranged in a factorial design with two foliar fertilization treatments, a foliar spray and a control to study the effects of commercial ...
Arrobas, Margarida   +8 more
core   +1 more source

Electrospun Gelatin/OSA‐Starch Nanofibers for Encapsulation and Controlled Release of Sage Extract

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 15, April 15, 2026.
Schematic representation of electrospun gelatin/OSA‐starch nanofibers encapsulating sage extract, illustrating fabrication, nanofiber formation, and sustained antioxidant release. ABSTRACT In recent years, increasing research efforts have focused on assessing the potential of polymeric nanofibers to improve the bioavailability and stability of active ...
Rozhin Mohagheghian   +4 more
wiley   +1 more source

Analysis of Active Components in Salvia Miltiorrhiza Injection Based on Vascular Endothelial Cell Protection

open access: yesActa Pharmaceutica, 2014
Correlation analysis based on chromatograms and pharmacological activities is essential for understanding the effective components in complex herbal medicines.
Shen Jie   +3 more
doaj   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao   +8 more
wiley   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou   +11 more
wiley   +1 more source

Salvianolic acid B ameliorates hepatocyte lipid droplet accumulation via stimulation of autophagy [PDF]

open access: yes, 2020
Abstract Salvianolic acid B (Sal B) the most abundant bioactive member in Salvia miltiorrhiza and has been reported lots of benefits on the treatment of cardio-cerebral vascular diseases and metabolic diseases. Lipid droplets are dynamic organelles, excessive lipid droplets accumulation in liver caused fatty liver disease. In this study, we are
Yanan Shi   +5 more
openaire   +2 more sources

Health-promoting effects of Thymus herba-barona, Thymus pseudolanuginosus, and Thymus caespititius decoctions [PDF]

open access: yes, 2017
Thymus herba-barona, Thymus pseudolanuginosus, and Thymus caespititius decoctions were screened for their phenolic constituents, along with their potential antioxidant, anti-inflammatory, and antibacterial activities.
Afonso, Andrea F.   +4 more
core   +1 more source

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