Results 71 to 80 of about 16,703 (172)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, Volume 15, Issue 20, 27 May 2026.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Sirt3 Genetically Engineered Apoptotic Bodies Alleviate Skeletal Aging by Limiting Aggravated NLRP3 Inflammasome Activation of Senescent Macrophages

Advanced Science, Volume 13, Issue 26, 8 May 2026.
The senescence of macrophages leads to a decrease in the expression of Sirtuin3 (Sirt3), which in turn aggravates the NLRP3 inflammasome activation and IL‐1β secretion, thereby promoting the aging‐related osteoporosis. Sirt3‐enriched apoptotic bodies (ABs‐Sirt3) generated through genetic editing approaches can alleviate skeletal aging by targeting ...
Yanglin Wu, Shifeng Ling, Jiayi Mao, Hongyi Wang, Bo Wang, Zhenjia Che, Wenguo Cui, Ming Cai   +7 more
wiley   +1 more source

In vitro Preparation and Evaluation of Sustained-Release Microcapsules of Salvianolic Acid

Drug Design, Development and Therapy, 2021
Yun-Hong Wang,1 Tong Qu,2 Xue-Lian Wang,3 Rong-Ping Yang3 1Chongqing Academy of Chinese Materia Medica, Chongqing, 400065, People’s Republic of China; 2Shaanxi University of Chinese Medicine, Xianyang, 712046, People’s Republic of China ...
Wang YH, Qu T, Wang XL, Yang RP
doaj  

Astragalus Salvia Granules to Benefit the Qi (Qishen Yiqi Keli) protects H9C2 cardiomyocytes by suppressing oxidative stress

Journal of Traditional Chinese Medical Sciences, 2016
Objective: To investigate the effects of Qishen Yiqi Keli (QSYQ; Astragalus Salvia Granules to Benefit the Qi) on ROS scavenging and inhibition of NADPH oxidase in an effort to identify new natural antioxidants.
Bangze Fu, Shuzhen Guo, Xue Yu, Hong Chang, Wei Wang   +4 more
doaj   +1 more source

Mechanisms of salvianolic acids in kidney disease therapy: advances and perspectives

Frontiers in Pharmacology
Kidney diseases, including acute kidney injury (AKI), chronic kidney disease (CKD), nephrotic syndrome (NS) and diabetic nephropathy (DN), represent a major global public health concern.
Jing Li, Xiaoqin Liu, Haoyue Feng
doaj   +1 more source

Preparation of controlled porosity osmotic pump tablets for salvianolic acid and optimization of the formulation using an artificial neural network method

Acta Pharmaceutica Sinica B, 2011
In this paper controlled porosity osmotic pump tablets (CPOPT) for salvianolic acid (SA) were prepared and optimized with experimental design methods including an artificial neutral network (ANN) method. Three causal factors, i.e., drug, osmotic pressure
Wen-Jin Xu, Ning Li, Chong-kai Gao
doaj   +1 more source

Clinical observation of salvianolic acid B in treatment of liver fibrosis in chronic hepatitis B

World Journal of Gastroenterology, 2002
To evaluate the clinical efficacy of salvianolic acid B (SA-B) on liver fibrosis in chronic hepatitis B.Sixty patients with definite diagnosis of liver fibrosis with hepatitis B were included in the trial. Interferon-gamma (IFN-gamma) was used as control drug.
Ping, Liu, Yi-Yang, Hu, Cheng, Liu, Da-Yuan, Zhu, Hui-Ming, Xue, Zhi-Qiang, Xu, Lie-Ming, Xu, Cheng-Hai, Liu, Hong-Tu, Gu, Zhi-Qing, Zhang   +9 more
openaire   +2 more sources

Isolation of Salvianolic acid A, a Minor Phenolic Carboxylic Acid of

Natural Product Communications, 2010
Salvianolic acid A (Sal A), a caffeic acid derivative present in Salvia miltiorrhiza (Danshen), has shown significant biological activities, some of which are more potent than those of salvianolic acid (Sal B), the most abundant and bioactive compound in
Luyang Lu, Hao Zhang, Yu Qian, Yuan Yuan
doaj   +1 more source

In vitro Preparation and Evaluation of Sustained-Release Microcapsules of Salvianolic Acid [Retraction]

Drug Design, Development and Therapy, 2021
Wang YH, Qu T, Wang XL, Yang RP. Drug Des Devel Ther. 2021;15:1623–1631. At the authors request, the Editor and Publisher of Drug Design, Development and Therapy wish to retract the published article.
Wang YH, Qu T, Wang XL, Yang RP
doaj  

Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis

World Journal of Gastroenterology, 2015
To investigate the effects of salvianolic acid B (Sal B) on the morphological characteristics and functions of liver mitochondria of rats with nonalcoholic steatohepatitis (NASH).A total of 60 male Sprague-Dawley rats were randomly divided into three groups: (1) a normal group fed a normal diet; (2) an NASH model group; and (3) a Sal B-treated group ...
Ying-Chun, Wang, Wei-Zong, Kong, Qing-Mei, Jin, Juan, Chen, Lei, Dong   +4 more
openaire   +2 more sources