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Salvianolic acid B: a promising cardioprotective agent [PDF]

open access: yesFrontiers in Immunology
Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma] is a core herb in traditional Chinese medicine widely used for treating cardiovascular diseases (CVD).
Yingchun Shao   +4 more
doaj   +4 more sources

Inhibition of Tanshinone IIA, Salvianolic Acid A and Salvianolic Acid B on Areca Nut Extract-Induced Oral Submucous Fibrosis in Vitro [PDF]

open access: yesMolecules, 2015
Salvia miltiorrhiza Bunge has been reported to possess excellent antifibrotic activity. In this study, we have investigated the effect and mechanism of tanshinone IIA (Tan-IIA), salvianolic acid A (Sal-A) and salvianolic acid B (Sal-B), the important ...
Jian-Ping Dai   +7 more
doaj   +5 more sources

Salvianolic Acid Modulates Physiological Responses and Stress-Related Genes That Affect Osmotic Stress Tolerance in Glycine max and Zea mays

open access: yesFrontiers in Plant Science, 2022
Drought is a serious threat worldwide to soybean and maize production. This study was conducted to discern the impact of salvianolic acid treatment on osmotic-stressed soybean (Glycine max L.) and maize (Zea mays L.) seedlings from the perspective of ...
Elham Ahmed Kazerooni   +5 more
doaj   +2 more sources

Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS

open access: yesInternational Journal of Analytical Chemistry, 2021
Salvianolic acid B is the main active ingredient in salvianolate injection, which is produced by extracting danshen, the most commonly used Chinese herbal medicine for cardiovascular treatment.
Weiyi Cao   +6 more
doaj   +2 more sources

Salvianolic Acid B Inhibits Ferroptosis in Acute Lung Injury: Network Analysis and Experimental Validation. [PDF]

open access: yesJ Cell Mol Med
ABSTRACT This current study aimed to decipher the anti‐inflammatory, anti‐ferroptosis and pronounced lung‐protective activities of Salvianolic acid B (Sal B) by integrating network pharmacology and experimental confirmation across multiple aspects. The optimal target protein and the relevant molecular mechanisms for Sal B in the context of ALI were ...
Gao H, Xiong R, Yue N, Wang J, Tian S.
europepmc   +2 more sources

Salvianolic Acid B: A Review of Pharmacological Effects, Safety, Combination Therapy, New Dosage Forms, and Novel Drug Delivery Routes

open access: yesPharmaceutics, 2023
Salvianolic acid B is extracted from the roots and rhizomes of Danshen (Salvia miltiorrhiza Bge., family Labiatae). It is a water-soluble, weakly acidic drug that has demonstrated antitumor and anti-inflammatory effects on various organs and tissues such
Guannan He   +6 more
doaj   +2 more sources

RETRACTION: Salvianolic Acid B-Induced MicroRNA-152 Inhibits Liver Fibrosis by Attenuating DNMT1-Mediated Patched1 Methylation. [PDF]

open access: yesJ Cell Mol Med
RETRACTION: F. Yu, Z. Lu, B. Chen, X. Wu, P. Dong, and J. Zheng, “Salvianolic Acid B‐Induced MicroRNA‐152 Inhibits Liver Fibrosis by Attenuating DNMT1‐Mediated Patched1 Methylation,” Journal of Cellular and Molecular Medicine 19, no. 11 (2015): 2617–2632, https://doi.org/10.1111/jcmm.12655. The above article, published online on 10 August 2015 in Wiley
europepmc   +2 more sources

M. canadensis and its active component salvianolic acid B overcome paclitaxel resistance in gastric cancer via ROS–ER stress signaling [PDF]

open access: yesCancer Cell International
Background Paclitaxel (PTX) is widely used for gastric cancer treatment; however, PTX resistance (PTXR) significantly limits clinical efficacy. Purpose To investigate the potential of Mentha canadensis and its bioactive component, salvianolic acid B, to ...
Bo Ram Kim   +8 more
doaj   +2 more sources

Repurposing SARS CoV 2 ligands identifies salvianolic acid C as potential antiviral candidate against human metapneumovirus through computational study [PDF]

open access: yesScientific Reports
Human Metapneumovirus (HMPV) is a leading cause of respiratory tract infections worldwide, with no approved antiviral treatments or vaccines currently available.
Pallavi Mosale Shanthappa   +2 more
doaj   +2 more sources

Inhibitory Effect of Salvia miltiorrhiza Extract and Its Active Components on Cervical Intraepithelial Neoplastic Cells

open access: yesMolecules, 2022
The effective treatment of cervical intraepithelial neoplasia (CIN) can prevent cervical cancer. Salvia miltiorrhiza is a medicinal and health-promoting plant. To identify a potential treatment for CIN, the effect of S.
Xuejiao Leng   +5 more
doaj   +1 more source

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