Results 41 to 50 of about 17,836 (133)

Inhibition of Tanshinone IIA, Salvianolic Acid A and Salvianolic Acid B on Areca Nut Extract-Induced Oral Submucous Fibrosis in Vitro

Molecules, 2015
Salvia miltiorrhiza Bunge has been reported to possess excellent antifibrotic activity. In this study, we have investigated the effect and mechanism of tanshinone IIA (Tan-IIA), salvianolic acid A (Sal-A) and salvianolic acid B (Sal-B), the important ...
Jian-Ping Dai, Dan-Xia Zhu, Jiang-Tao Sheng, Xiao-Xuan Chen, Wei-Zhong Li, Ge-Fei Wang, Kang-Sheng Li, Yun Su   +7 more
doaj   +1 more source

Activation of AMP-Activated Protein Kinase-Sirtuin 1 Pathway Contributes to Salvianolic Acid A-Induced Browning of White Adipose Tissue in High-Fat Diet Fed Male Mice

Frontiers in Pharmacology, 2021
Background: Salvianolic acid A (Sal A), a natural polyphenolic compound extracted from Radix Salvia miltiorrhiza (Danshen), exhibits exceptional pharmacological activities against cardiovascular diseases.
Jianfei Lai, Jianfei Lai, Qianyu Qian, Qianyu Qian, Qinchao Ding, Qinchao Ding, Qinchao Ding, Li Zhou, Ai Fu, Zhongyan Du, Cui Wang, Cui Wang, Zhenyuan Song, Songtao Li, Songtao Li, Xiaobing Dou, Xiaobing Dou   +16 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Cloning and characterization of a putative R2R3 MYB transcriptional repressor of the rosmarinic acid biosynthetic pathway from Salvia miltiorrhiza.

PLoS ONE, 2013
Salvia miltiorrhiza Bunge is one of the most renowned traditional medicinal plants in China. Phenolic acids that are derived from the rosmarinic acid pathway, such as rosmarinic acid and salvianolic acid B, are important bioactive components in S ...
Shuncang Zhang, Pengda Ma, Dongfeng Yang, Wenjing Li, Zongsuo Liang, Yan Liu, Fenghua Liu   +6 more
doaj   +1 more source

The combination of salvianolic acid A with latamoxef completely protects mice against lethal pneumonia caused by methicillin-resistant Staphylococcus aureus

Emerging Microbes and Infections, 2020
Staphylococcus aureus (S. aureus), especially methicillin-resistant Staphylococcus aureus (MRSA), is a major cause of pneumonia, resulting in severe morbidity and mortality in adults and children.
Dan Mu, Yongxin Luan, Lin Wang, Zeyuan Gao, Panpan Yang, Shisong Jing, Yanling Wang, Hua Xiang, Tiedong Wang, Dacheng Wang   +9 more
doaj   +1 more source

First Synthesis of Shimobashiric Acid C With Acetonide as the Catechol Protecting Group

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
ABSTRACT Shimobashiric acid C (SBA‐C) shows excellent hyaluronidase inhibition but its natural isolation yield is only 0.0092 %. We report its first synthesis via a convergent seven‐step route from caffeic and rosmarinic acids in 35% overall yield.
Ruwen Li, Zhe Zhang, Pengshu Xu, Lin Zhou, Lei Chen, Zhongqiang Liu   +5 more
wiley   +1 more source

Experimental and theoretical assessment of salvianolic acid B, ellagic acid, and phorbol esters as drug candidates against breast and prostate cancer

Discover Chemistry
Global efforts to develop innovative anti-cancer lead compounds from natural compounds found in plants have gained advanced momentum, focusing on achieving Sustainable Development Goal (SDG) number 3 on good health and well-being.
Russell B. O. Ouma, Usama Raza, Silas M. Ngari, Joshua K. Kibet, Uzair Nisar, Muhammad Waqar Ali   +5 more
doaj   +1 more source

Astragalus Salvia Granules to Benefit the Qi (Qishen Yiqi Keli) protects H9C2 cardiomyocytes by suppressing oxidative stress

Journal of Traditional Chinese Medical Sciences, 2016
Objective: To investigate the effects of Qishen Yiqi Keli (QSYQ; Astragalus Salvia Granules to Benefit the Qi) on ROS scavenging and inhibition of NADPH oxidase in an effort to identify new natural antioxidants.
Bangze Fu, Shuzhen Guo, Xue Yu, Hong Chang, Wei Wang   +4 more
doaj   +1 more source

An Integrated Metabolomics and Bioactivity Approach to Characterize Salvia heldreichiana and Salvia tomentosa Extracts

ChemistryOpen, Volume 15, Issue 10, October 2026.
S. heldreichiana and S. tomentosa can be considered as effective sources of natural bioactive agents for further in vivo pharmacological evaluation and development. The genus Salvia, widely known as sage, represents the largest group within the Lamiaceae family and includes numerous species with traditional uses.
Gokhan Zengin, Nilofar Nilofar, Alina Kalyniukova, Vasil Andruch, Giancarlo Angeles Flores, Paola Angelini, Roberto Venanzoni, Kubra Aslan, Ilhami Gulcin, Evren Yildiztugay   +9 more
wiley   +1 more source

Rosmarinic Acid Derivatives’ Inhibition of Glycogen Synthase Kinase-3β Is the Pharmacological Basis of Kangen-Karyu in Alzheimer’s Disease

Molecules, 2018
Inhibition of glycogen synthase kinase 3β (GSK-3β) is considered to be the central therapeutic approach against Alzheimer’s disease (AD).
Pradeep Paudel, Su Hui Seong, Yajuan Zhou, Chan Hum Park, Takako Yokozawa, Hyun Ah Jung, Jae Sue Choi   +6 more
doaj   +1 more source