Results 61 to 70 of about 19,711 (218)

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Visualizing the spatial distribution and alteration of metabolites in continuously cropped Salvia miltiorrhiza Bge using MALDI-MSI

Journal of Pharmaceutical Analysis, 2022
Salvia miltiorrhiza Bge (SMB) has long been used in traditional Chinese medicine to treat cardiovascular and cerebrovascular diseases. Growing clinical usage has led to a huge demand for artificial planting of SMB.
Chenglong Sun, Li Cui, Bingqian Zhou, Xiao Wang, Lanping Guo, Wei Liu   +5 more
doaj   +1 more source

Rosemary extracts in functional foods: extraction, chemical characterization and incorporation of free and microencapsulated forms in cottage cheese [PDF]

, 2016
Consumers search for food with functional characteristics beyond its nutritional properties. Thus, the concept of functional food has become a hot topic, allowing us to obtain additional health benefits, including disease prevention.
Barreiro, M.F., Barros, Lillian, Caleja, Cristina, Ferreira, Isabel C.F.R., Ribeiro, Andreia, Santos-Buelga, Celestino   +5 more
core   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Inhibition of TLR4/MAPKs Pathway Contributes to the Protection of Salvianolic Acid A Against Lipotoxicity-Induced Myocardial Damage in Cardiomyocytes and Obese Mice

Frontiers in Pharmacology, 2021
The occurrence of lipotoxicity during obesity-associated cardiomyopathy is detrimental to health. Salvianolic acid A (SAA), a natural polyphenol extract of Salvia miltiorrhiza Bunge (Danshen in China), is known to be cardioprotective.
Zhen Yang, Zhen Yang, Zhen Yang, Yanli Chen, Yanli Chen, Zhaoyuan Yan, Tian Tian Xu, Xiangyao Wu, Aiwen Pi, Qingsheng Liu, Hui Chai, Hui Chai, Songtao Li, Songtao Li, Xiaobing Dou, Xiaobing Dou   +15 more
doaj   +1 more source

Endophyte Chaetomium globosum D38 Promotes Bioactive Constituents Accumulation and Root Production in Salvia miltiorrhiza [PDF]

, 2018
Salvia miltiorrhiza is known for tanshinones and salvianolic acids, which have been shown to have a protective effect against ROS, especially for cardiovascular diseases and other various ailments of human organs.
Han, T, Ji, J, Jia, M, Kong, Z, Li, X, Luo, D, Qin, L, Rahman, K, Zhai, X, Zheng, C   +9 more
core   +3 more sources

Salvianolic acid-A alleviates oxidative stress-induced osteoporosis

Life Sciences
Cellular damage induced by oxidative stress contributes to systemic bone disorders leading to osteoporosis. Bone homeostasis regulates the balance between the functions of osteoblasts and osteoclasts. Osteoblast cells are responsible for bone formation and are very sensitive to oxidative stress.
Ayaan, Khan, Hope, Sabella, Venkata Kiran Kumar, Mandlem, Farah, Deba   +3 more
openaire   +2 more sources

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Activation of AMP-Activated Protein Kinase-Sirtuin 1 Pathway Contributes to Salvianolic Acid A-Induced Browning of White Adipose Tissue in High-Fat Diet Fed Male Mice

Frontiers in Pharmacology, 2021
Background: Salvianolic acid A (Sal A), a natural polyphenolic compound extracted from Radix Salvia miltiorrhiza (Danshen), exhibits exceptional pharmacological activities against cardiovascular diseases.
Jianfei Lai, Jianfei Lai, Qianyu Qian, Qianyu Qian, Qinchao Ding, Qinchao Ding, Qinchao Ding, Li Zhou, Ai Fu, Zhongyan Du, Cui Wang, Cui Wang, Zhenyuan Song, Songtao Li, Songtao Li, Xiaobing Dou, Xiaobing Dou   +16 more
doaj   +1 more source

Sirt3 Genetically Engineered Apoptotic Bodies Alleviate Skeletal Aging by Limiting Aggravated NLRP3 Inflammasome Activation of Senescent Macrophages

Advanced Science, Volume 13, Issue 26, 8 May 2026.
The senescence of macrophages leads to a decrease in the expression of Sirtuin3 (Sirt3), which in turn aggravates the NLRP3 inflammasome activation and IL‐1β secretion, thereby promoting the aging‐related osteoporosis. Sirt3‐enriched apoptotic bodies (ABs‐Sirt3) generated through genetic editing approaches can alleviate skeletal aging by targeting ...
Yanglin Wu, Shifeng Ling, Jiayi Mao, Hongyi Wang, Bo Wang, Zhenjia Che, Wenguo Cui, Ming Cai   +7 more
wiley   +1 more source