Results 81 to 90 of about 19,711 (218)

The Role of Piezo 1 in the Study of Intervertebral Disc Degeneration: Phenotype, Mechanism and Treatment

Orthopaedic Surgery, Volume 18, Issue 5, Page 897-914, May 2026.
As the key mechanotransducer in IVDD, Piezo1 orchestrates region‐specific degeneration across NP (senescence/ECM dysregulation), AF (apoptosis), and CEP (inflammation). This review integrates mechanistic pathways and assesses multimodal therapeutic targeting (pharmacologic/genetic/nutritional) to restore disc homeostasis.
Guangye Li, Chaoqun Feng, Haoyun Huang, Junwen Deng, Fei Yang, Rigao Chen   +5 more
wiley   +1 more source

Targeting neurogenesis: a promising therapeutic strategy for post-stroke treatment with Chinese herbal medicine [PDF]

, 2014
published_or_final_versio
Chen, X, Chen, X, Deng, R, Shen, J
core   +1 more source

Rosmarinic Acid Derivatives’ Inhibition of Glycogen Synthase Kinase-3β Is the Pharmacological Basis of Kangen-Karyu in Alzheimer’s Disease

Molecules, 2018
Inhibition of glycogen synthase kinase 3β (GSK-3β) is considered to be the central therapeutic approach against Alzheimer’s disease (AD).
Pradeep Paudel, Su Hui Seong, Yajuan Zhou, Chan Hum Park, Takako Yokozawa, Hyun Ah Jung, Jae Sue Choi   +6 more
doaj   +1 more source

Mycorrhizal fungi were more effective than zeolites in increasing the growth of non-irrigated young olive trees [PDF]

, 2020
Four soil treatments, consisting of two commercial mycorrhizal fungi, one zeolite and an untreated control, were arranged in a factorial design with two foliar fertilization treatments, a foliar spray and a control to study the effects of commercial ...
Arrobas, Margarida, Brito, Cátia, Correia, Carlos M., Gonçalves, Alexandre, Lopes, João Ilídio, Martins, Sandra, Raimundo, Soraia, Rodrigues, M.A., Silva, Ermelinda   +8 more
core   +1 more source

Electrospun Gelatin/OSA‐Starch Nanofibers for Encapsulation and Controlled Release of Sage Extract

Journal of Applied Polymer Science, Volume 143, Issue 15, April 15, 2026.
Schematic representation of electrospun gelatin/OSA‐starch nanofibers encapsulating sage extract, illustrating fabrication, nanofiber formation, and sustained antioxidant release. ABSTRACT In recent years, increasing research efforts have focused on assessing the potential of polymeric nanofibers to improve the bioavailability and stability of active ...
Rozhin Mohagheghian, Akram Pezeshki, Babak Ghanbarzadeh, Maryam Mohammadi, M. Ali Aboudzadeh   +4 more
wiley   +1 more source

Experimental and theoretical assessment of salvianolic acid B, ellagic acid, and phorbol esters as drug candidates against breast and prostate cancer

Discover Chemistry
Global efforts to develop innovative anti-cancer lead compounds from natural compounds found in plants have gained advanced momentum, focusing on achieving Sustainable Development Goal (SDG) number 3 on good health and well-being.
Russell B. O. Ouma, Usama Raza, Silas M. Ngari, Joshua K. Kibet, Uzair Nisar, Muhammad Waqar Ali   +5 more
doaj   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

Advanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao, Ao Zheng, Zhengyan Zhao, Qilin Li, Tianhao Wan, Tanjun Deng, Ying Zhang, Lingyan Cao, Lan Wu   +8 more
wiley   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on "system to system" mode [PDF]

, 2012
The electronic version of this article is the complete one and can be found online at: http://www.translational-medicine.com/content/10/1/26 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http ...
Guo-An Luo, Hong-Yang Zhang, Jun Wu, Qing-Bo Xu, Qing-Li Zhang, Qing-Zhong Xiao, Qiong-Lin Liang, Rong Gao, Rong-Li Zhang, Shu-Feng Lv, Xi Chen, Xiao-Ping Liang, Xue Li, Xue-Mei Fan, Yi-Jun Cheng, Yi-Ming Wang, Yuan-Yuan Xie   +16 more
core   +2 more sources

Antioxidant and Antifungal Effects of Lavandula stoechas Aqueous Extract Against Aspergillus niger and Fusarium oxysporum as a Potential Natural Preservative and Crop Protection Agent in the Agrifood Sector

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
Phytochemical Investigation and Antioxidant and Antifungal Effects of Lavandula stoechas Aqueous Extract. ABSTRACT The antioxidant and antifungal activities of (Lavandula stoechas) L. stoechas aqueous extract were studied to examine their potential application against food and crop spoilage.
Imane Namoune, Fairouz Boubrik, Rima Yakoubi, Lynda Gali, Djamila Benouchenne, Samira Bendjedid, Hadj Sadok Tahar, Salim Terriche, Hamdi Bendif, Anis Ahmad Chaudhary, Tarek H. Taha, Walid Elfalleh, Stefania Garzoli   +12 more
wiley   +1 more source