Results 91 to 100 of about 667,703 (231)

Salvianolic acid B attenuates experimental skin fibrosis of systemic sclerosis

Biomedicine & Pharmacotherapy, 2019
Systemic sclerosis (SSc) is a connective tissue disease characterized mainly by fibrosis of skin and internal organs. Our previous study has shown that salvianolic acid B (SAB), a bioactive component extracted from Salvia miltiorrhiza (SM), was one of the essential ingredients in the traditional Chinese medicine Yiqihuoxue formula, which has been used ...
Qingmei, Liu, Jiaying, Lu, Jinran, Lin, Yulong, Tang, Weilin, Pu, Xiangguang, Shi, Shuai, Jiang, Jing, Liu, Yanyun, Ma, Yuan, Li, Jinhua, Xu, Li, Jin, Jiucun, Wang, Wenyu, Wu   +13 more
openaire   +2 more sources

Cardiovascular Benefits of Salvia miltiorrhiza (Danshen) Supplementation: Bioactive Constituents, Mechanisms, Clinical Evidence and Implications for Nutritional Care

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Salvia miltiorrhiza (Danshen) contains bioactive tanshinones, including tanshinone IIA, cryptotanshinone, and tanshinone I, that exert cardioprotective effects through coordinated modulation of vascular endothelial growth factor receptor (VEGFR), transforming growth factor beta 1 (TGF‐β1), transforming growth factor beta receptor (TGF‐βR), toll‐like ...
Akash Vikal, Rashmi Maurya, Preeti Patel, Balak Das Kurmi, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu, Wenqing Qin, Minghang Dong, Zhi Ma, Si Li, Runping Liu, Ranyun Chen, Changmeng Li, Xiaojiaoyang Li   +8 more
wiley   +1 more source

Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity [PDF]

Phytomedicine, 2014
Salvianolic acid A (Sal A), an important constituent of Radix Salviae Miltiorrhizae (RSM), is effective for the treatment of myocardial infarction (MI) and coronary heart disease due to its potential in the improvement of acute myocardial ischemia. However, its content is very low in RSM.
Hongrui, Xia, Longru, Sun, Hongxiang, Lou, M Mukhlesur, Rahman   +3 more
openaire   +2 more sources

R2R3-MYB Transcription Factor SmMYB52 Positively Regulates Biosynthesis of Salvianolic Acid B and Inhibits Root Growth in Salvia miltiorrhiza [PDF]

, 2021
Rao Yang, Shengsong Wang, Haolan Zou, Lin Li, Yonghui Li, Donghao Wang, Hongxing Xu, Xiaoyan Cao   +7 more
openalex   +1 more source

SALVIANOLIC ACID B ALLEVIATING MYOCARDIUM INJURY IN ISCHEMIA REPERFUSION RATS.

African journal of traditional, complementary, and alternative medicines : AJTCAM, 2016
Salvia miltiorrhiza (SM) Bunge is one of the widely-used Chinese medicinal herbs. Salvianolic acid B (Sal B), a bioactive compound isolated from the Chinese herb Radix Salviae Miltiorrhizae, has been reported to exhibit anti-inflammatory and anti-oxidantive effects.To study the cardioprotective effects of salvianolic acid B (Sal B) on acute myocardial ...
Qiao, Zengyong, Xu, Yawei
openaire   +3 more sources

The Role of Piezo 1 in the Study of Intervertebral Disc Degeneration: Phenotype, Mechanism and Treatment

Orthopaedic Surgery, Volume 18, Issue 5, Page 897-914, May 2026.
As the key mechanotransducer in IVDD, Piezo1 orchestrates region‐specific degeneration across NP (senescence/ECM dysregulation), AF (apoptosis), and CEP (inflammation). This review integrates mechanistic pathways and assesses multimodal therapeutic targeting (pharmacologic/genetic/nutritional) to restore disc homeostasis.
Guangye Li, Chaoqun Feng, Haoyun Huang, Junwen Deng, Fei Yang, Rigao Chen   +5 more
wiley   +1 more source

Analysis of Active Components in Salvia Miltiorrhiza Injection Based on Vascular Endothelial Cell Protection

Acta Pharmaceutica, 2014
Correlation analysis based on chromatograms and pharmacological activities is essential for understanding the effective components in complex herbal medicines.
Shen Jie, Yang Kai, Sun Caihua, Zheng Minxia   +3 more
doaj   +1 more source

Effects and Mechanism of Salvianolic Acid B on the Injury of Human Renal Tubular Epithelial Cells Induced by Iopromide [PDF]

, 2021
Shujun Dong, Xinyue Gao, Mingxin Pei, Ting Luo, Fan Dong, Yanling Chen, Jin Jun-feng, Xiaoduo Zhao   +7 more
openalex   +1 more source

Electrospun Gelatin/OSA‐Starch Nanofibers for Encapsulation and Controlled Release of Sage Extract

Journal of Applied Polymer Science, Volume 143, Issue 15, April 15, 2026.
Schematic representation of electrospun gelatin/OSA‐starch nanofibers encapsulating sage extract, illustrating fabrication, nanofiber formation, and sustained antioxidant release. ABSTRACT In recent years, increasing research efforts have focused on assessing the potential of polymeric nanofibers to improve the bioavailability and stability of active ...
Rozhin Mohagheghian, Akram Pezeshki, Babak Ghanbarzadeh, Maryam Mohammadi, M. Ali Aboudzadeh   +4 more
wiley   +1 more source