Results 11 to 20 of about 16,703 (172)

Ginsenoside Rb1, salvianolic acid B and their combination modulate gut microbiota and improve glucolipid metabolism in high-fat diet induced obese mice [PDF]

PeerJ, 2021
Background To observe the effect of ginsenoside Rb1, salvianolic acid B and their combination on glucolipid metabolism and structural changes of gut microbiota. Methods Eight-week-old C57BL/6J mice were fed 45% high-fat diet to induce obesity.
Ying Bai, Xueli Bao, Qianqian Mu, Xin Fang, Ruyuan Zhu, Chenyue Liu, Fangfang Mo, Dongwei Zhang, Guangjian Jiang, Ping Li, Sihua Gao, Dandan Zhao   +11 more
doaj   +2 more sources

M. canadensis and its active component salvianolic acid B overcome paclitaxel resistance in gastric cancer via ROS-ER stress signaling. [PDF]

Cancer Cell Int
Background Paclitaxel (PTX) is widely used for gastric cancer treatment; however, PTX resistance (PTXR) significantly limits clinical efficacy. Purpose To investigate the potential of Mentha canadensis and its bioactive component, salvianolic acid B, to ...
Kim BR, Yeo H, Park SM, Jang S, Yun HM, Hwang YH, Lee SI, Oh SC, Kang HN.   +8 more
europepmc   +2 more sources

Neuroprotective Effects of Geopung-Chunghyuldan Based on Its Salvianolic Acid B Content Using an In Vivo Stroke Model

Current Issues in Molecular Biology, 2023
Background: Geopung-Chunghyuldan (GCD) has neuroprotective properties. Salviae miltiorrhizae Radix plays an essential role in GCD’s effect. The Salviae miltiorrhizae Radix marker compound is salvianolic acid B; however, its content is not uniform among ...
Han-Gyul Lee, Seungwon Kwon, Sang-Kwan Moon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Jung-Mi Park, Chang-Nam Ko, Ki-Ho Cho   +8 more
doaj   +1 more source

Salvianolic acid B alleviates cartilage tissue damage in rat models with osteoarthritis [PDF]

Jichu yixue yu linchuang, 2023
Objective To explore whether salvianolic acid B affects cartilage tissue damage, hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF) in osteoarthritis rats. Methods A rat model of osteoarthritis was constructed, and rats were
QIAN Ligang, SUN Bo, YU Bo, CHEN Kang, MA Zheng, CHEN Taoping, WANG Yunfei
doaj   +1 more source

Salvianolic acid-B improves fat graft survival by promoting proliferation and adipogenesis

Stem Cell Research & Therapy, 2021
Background Our previous study proved that Salvia miltiorrhiza could enhance fat graft survival by promoting adipogenesis. However, the effect of salvianolic acid B (Sal-B), the most abundant and bioactive water-soluble compound in Salvia miltiorrhiza, on
Jia-Ming Sun, Chia-Kang Ho, Ya Gao, Chio-Hou Chong, Dan-Ning Zheng, Yi-Fan Zhang, Li Yu   +6 more
doaj   +1 more source

Salvianolic Acid B: A Review of Pharmacological Effects, Safety, Combination Therapy, New Dosage Forms, and Novel Drug Delivery Routes

Pharmaceutics, 2023
Salvianolic acid B is extracted from the roots and rhizomes of Danshen (Salvia miltiorrhiza Bge., family Labiatae). It is a water-soluble, weakly acidic drug that has demonstrated antitumor and anti-inflammatory effects on various organs and tissues such
Guannan He, Guangfeng Chen, Weidong Liu, Dongxue Ye, Xuehuan Liu, Xiaodong Liang, Jing Song   +6 more
doaj   +1 more source

Ultrasonic-assisted nanofiltration separation recovering salvianolic acid B from ethanol wastewater. [PDF]

Ultrason Sonochem
The transformation of salvianolic acid B brought on by heat treatment recovery of ethanol eluent, which is a difficult problem in pharmaceutical technology, affects the purity of raw material when the medicinal raw material salvianolic acid B is purified
Li C, Ma Y, Xu Y, Qiu R, Shen X, Huang L, Liu A, Li M, Zheng Y, Zhi X.   +9 more
europepmc   +2 more sources

Inhibitory Effect of Salvia miltiorrhiza Extract and Its Active Components on Cervical Intraepithelial Neoplastic Cells

Molecules, 2022
The effective treatment of cervical intraepithelial neoplasia (CIN) can prevent cervical cancer. Salvia miltiorrhiza is a medicinal and health-promoting plant. To identify a potential treatment for CIN, the effect of S.
Xuejiao Leng, Hongfei Kan, Qinhang Wu, Cunyu Li, Yunfeng Zheng, Guoping Peng   +5 more
doaj   +1 more source

Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS

International Journal of Analytical Chemistry, 2021
Salvianolic acid B is the main active ingredient in salvianolate injection, which is produced by extracting danshen, the most commonly used Chinese herbal medicine for cardiovascular treatment.
Weiyi Cao, Hezhi Yao, Zhenzhen Qian, Yi Wu, Shuge Wang, Rui Li, Rui Gao   +6 more
doaj   +1 more source

Salvianolic acid B attenuates renal interstitial fibrosis in rats with unilateral ureteral obstruction via Nrf2-Gpx4 pathway-mediated ferroptosis

Di-san junyi daxue xuebao, 2022
Objective To determine the improving effect of salvianolic acid B on renal interstitial fibrosis (RIF) of rats with unilateral ureteral obstruction (UUO) based on ferroptosis mediated by nuclear factor erythroid 2-related factor 2 (Nrf2)-glutathione ...
SUN Yuanbo, SONG Yanran, WANG Shiqi, SUN Lixin, LI Guiqin   +4 more
doaj   +1 more source