Results 101 to 110 of about 4,552 (200)

Cryptotanshinone and tanshinone IIA from Salvia milthorrhiza Bunge (Danshen) as a new class of potential pancreatic lipase inhibitors

, 2019
Salvia miltiorrhiza Bunge extract was investigated for the first time for its inhibitory activity against pancreatic lipase (PL), an important enzyme involved in the digestion of dietary fats.
Mariangela Marrelli (699983), Fedora Grande (6713147), Maria Antonietta Occhiuzzi (6713150), Filomena Conforti (699985), Francesco Maione (127366), Nicola Mascolo (127387)   +5 more
core   +1 more source

Isolation and quantitative analysis of cryptotanshinone, an active quinoid diterpene formed in callus of Salvia miltiorrhiza BUNGE

, 2014
Effect of N-6-benzyladenine (BA) on tanshinone formation in callus cultures of Salvia miltiorrhiza was examined in an attempt to increase the productivity of the medicinal compound, cryptotanshinone.
Nalawade, S.M., Yang, T.F., Tsay, H.S., Mulabagal, V., Wu, C.T., Chen, C.L.   +5 more
core  

Ethosomes Loaded with Cryptotanshinone for Acne Treatment through Topical Gel Formulation - Fig 5

, 2016
Photomicrographs (400×) of hematoxylin-eosin stained normal rabbit back skin (A), rabbit skin treated with blank ethosomal gel (B) and rabbit skin treated with cryptotanshinone loaded ethosomal gel (C).
Ke Ma (260231), Zhenwei Yu (3148452), Gang Han (127634), Hongyan Lv (3148455)   +3 more
core   +1 more source

Cryptotanshinone promote ferroptosis in glioblastoma via KEAP1/NRF2/HMOX1 signaling pathway

RNA-seq revealed that Cryptotanshinone induced up-regulation of ferroptosis pathway in U251 ...
hu, jiateng
core   +1 more source

Abstract P4-06-21: Matrix Metalloproteinase 2 in Tumor Cell-Induced Platelet Aggregation: Regulation by Cryptotanshinone

, 2010
Background: A correlation exists between the ability of tumor cells to aggregate platelets and their tendency to metastasize. Tumor cell-induced platelet aggregation (TCIPA) facilitates the embolization of the vasculature with tumor cells and the ...
L Yin, T. Li, Z Lei, Y Linggeng, H Chenhu, R Junshan   +5 more
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Effect of Harvest Time on Growth and Bioactive Compounds in Salvia miltiorrhiza

Plants
Danshen (Salvia miltiorrhiza) is a perennial medicinal plant belonging to the Lamiaceae family. It is adapted to a wide range of soil pH with the potential to serve as an alternative crop in the United States.
Zhiheng Xing, Guihong Bi, Tongyin Li, Qianwen Zhang, Patricia R. Knight   +4 more
doaj   +1 more source

DLX3 protein homeostasis disruption contributes to osimertinib-induced cutaneous toxicity and is rescued by cryptotanshinone

Osimertinib, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor, is widely used for the treatment of epidermal growth factor receptor-mutant non-small cell lung cancer.
Jiabin Lu, Peihua Luo, Renhua Gai, Baoli He, Congying Wang, Bo Yang, Xiaochun Yang, Qiaojun He, Yujia Weng, Hao Yan   +9 more
core   +1 more source

The in-silico identification and optimization of phytochemicals as potential inhibitors of tryptophan 2,3-dioxygenase in glioblastoma: A molecular docking and molecular dynamics-based approach

In Silico Research in Biomedicine
Tryptophan 2,3-dioxygenase (TDO2) promotes tryptophan catabolism through the kynurenine pathway and can contribute to an immunosuppressive tumor microenvironment, making it an attractive metabolic target in glioblastoma.
Siddhant Pandita, Vikas Jha
doaj   +1 more source

Supplementary Figures 1-3 from Cryptotanshinone Inhibits Cancer Cell Proliferation by Suppressing Mammalian Target of Rapamycin–Mediated Cyclin D1 Expression and Rb Phosphorylation

, 2010
Supplementary Figures 1-3 from Cryptotanshinone Inhibits Cancer Cell Proliferation by Suppressing Mammalian Target of Rapamycin–Mediated Cyclin D1 Expression and Rb ...
Shile Huang (315743), Zhijun Liu (35566), Hongyu Zhou (352858), Baoshan Xu (158726), Yin Lu (381049), Xiuzhen Han (352860), Tao Shen (209797), Wenxing Chen (352859), Lei Liu (5074), Yan Luo (255674)   +9 more
core   +1 more source

Cryptotanshinone and tanshinone IIA enhance IL-15-induced natural killer cell differentiation

, 2012
Natural killer (NK) cells are a subset of lymphocytes crucial for innate and adaptive immune responses. Here we show a stimulatory effect of cryptotanshinone (CTS) and tanshinone IIA (TS), isolated from Salvia miltiorrhiza Bunge, on the differentiation ...
Suk Ran Yoon, Dong Oh Kim, Mi Jeong Kim, In Pyo Choi, Haiyoung Jung, Inpyo Choi, Sung Jin Yoon, Byoung-Mog Kwon, Won Sam Kim, Young-Jun Park, Tae-Don Kim   +10 more
core   +1 more source