Results 71 to 80 of about 4,552 (200)
, 2016 Activating mutations of PTPN11 (encoding the SHP2 phosphatase) are associated with Noonan syndrome, childhood leukemias, and sporadic solid tumors. Virtual screening combined with experimental assays was performed to identify inhibitors of SHP2 from a ...
Gang Xu (219455) +6 more
core +1 more source
Effect of Plant Density on Growth and Bioactive Compounds in Salvia miltiorrhiza
AgronomyDanshen (Salvia miltiorrhiza) is an herbaceous plant widely used in the pharmaceutical industry. However, the majority of medicinal plants utilized in the US are imported, posing challenges such as fluctuations in bioactive compound concentrations and ...
Zhiheng Xing +4 more
doaj +1 more source
Folia Histochemica et Cytobiologica, 2023 INTRODUCTION: Hemorrhagic shock (HS) is an important cause of high mortality in traumatized patients. Cryptotanshinone (CTS) is a bioactive compound extracted from Salvia miltiorrhiza Bunge (Danshen).
Jiahui Han +5 more
doaj +1 more source
Genome‐Wide Transcriptional Profiling of the Response of Staphylococcus aureus to Cryptotanshinone [PDF]
BioMed Research International, 2009 Staphylococcus aureus (S. aureus) strains with multiple antibiotic resistances are increasingly widespread, and new agents are required for the treatment of S. aureus. Cryptotanshinone (CT), a major tanshinone of medicinal plant Salvia miltiorrhiza Bunge, demonstrated effective in vitro antibacterial activity against all 21 S.
Feng, Haihua +8 more
openaire +2 more sources
, 2013 Danshen is one of the most famous herbs in the world, and more and more danshen-prescribed drugs interactions have been reported in recent years. Evaluation of inhibition potential of danshen's major ingredients towards UDP-glucuronosyltransferases (UGTs)
Wang, Jia-Rui +6 more
core +1 more source
, 2007 Cryptotanshinone is the major active component from the root of Salvia miltiorrhiza which has been widely used for the management of coronary heart disease.
Bi, Huichang +8 more
core +2 more sources
Mediators of InflammationBackground. Bladder cancer (BC) is one of the most common malignancies of the urogenital system. This study assessed the nucleotide-binding oligomerization domain and leucine-rich repeat and pyrin domain-containing protein 3 (NLRP3) in BC as well as the ...
Chenye Tang +9 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2018 Cryptotanshinone (CTS) has emerged as an anti-inflammatory agent in osteoarthritis (OA). However, the molecular mechanism underlying its potent therapeutic effect on OA remains largely unknown.
Quanbo Ji +9 more
doaj +1 more source
Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity
Advanced Science, Volume 13, Issue 33, 15 June 2026.Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu +8 more
wiley +1 more source
The radiosensitizing effects of cryptotanshinone on H22 hepatoma-bearing mice
Zhongguo aizheng zazhi, 2014 Background and purpose: Quinonoids can change the cell cycle distribution of tumor cells, and effect the radiosensitizing. This study aimed to investigate the radiosensitization effects, cell cycle and apoptosis of cryptotanshinone on H22 hepatoma ...
叶因涛 +4 more
doaj