Results 71 to 80 of about 1,125,262 (294)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Fabrication and Optical Properties of 2at.%Yb:LuYAG Mixed Crystal through Nanocrystalline Powders
Crystals, 2018 Ytterbium doped Lu1.5Y1.5Al5O12 (LuYAG) nanocrystalline powders were synthesized by a wet chemical mixed precipitant co-precipitation (MPP) method, and then the mixed crystal of Yb:LuYAG was grown in an optical floating zone (OFZ) furnace at the speed of
Ding Zhou +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
CrystalsA series of lithium niobate crystals co-doped with uranium and indium was successfully grown by the modified vertical Bridgman method for the first time.
Tian Tian +7 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Journal of Materials Research and Technology, 2019 In this paper, we focused on microwave sintered NiTiO3 nanoparticles synthesized via sol–gel method. The crystal structure was determined by the X-ray diffraction.
Pavithra C., Madhuri W.
doaj +1 more source
How crystals that sense and respond to their environments could evolve [PDF]
, 2008 An enduring mystery in biology is how a physical entity simple enough to have arisen spontaneously could have evolved into the complex life seen on Earth today.
Schulman, Rebecca, Winfree, Erik
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Journal of Science: Advanced Materials and Devices, 2018 Terbium doped Sulfamic Acid (Tb3+:SA) single crystals were grown successfully by the slow evaporation solution (SEST) technique and the unidirectional method.
B. Brahmaji +7 more
doaj +1 more source