Results 51 to 60 of about 228,093 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Surface morphology and deformation mechanism of single crystal copper treated by laser shock peening [PDF]

open access: yes, 2014
To study the relation between surface morphology and deformation mechanism of the target material under the shock, a flexible boundary loading, in laser shock peening(LSP), the macroscopic and microscopic surface morphology of a single crystal copper ...
王曦, 黄晨光, Liu YX, 吴先前
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Controlling the crystal packing and morphology of metal–organic macrocycles through side-chain modification [PDF]

open access: yes
Supramolecular nanotubes constructed from the self-assembly of conjugated metal–organic macrocycles provide a unique collection of materials properties, including solution processability, porosity, and electrical conductivity.
Audrey, Hill   +4 more
core   +1 more source

Surface morphology, crystal structure and orientation of aluminium coatings electrodeposited on mild steel in ionic liquid [PDF]

open access: yes, 2009
Galvano-static electrodeposition was used to electrodeposit aluminium on mild steel in AlCl(3)/[bmim]Cl (1-butyl-3-methylimidazolium chloride) ionic liquid at variable temperatures (308-328 K).
Yue, Guikuan   +5 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

What can electron microscopy tell us beyond crystal structures? [PDF]

open access: yes, 2016
WZ thanks Professor Jun Yuan for a useful discussion during the revision of this article. The authors wish to thank EPSRC for financial support to the electron microscopy facility (No. EP/F019580/1) and a Platform grant (No. EP/K015540/1).
Zhou, Wuzong, Greer, Heather Frances
core   +1 more source

Effects of Different Shade Treatments on the Epidermal Wax Deposition of Hosta Genotypes with Different Glaucousness of Leaf Surface

open access: yesHorticulturae
Epidermal wax is strategically situated at the interface between plants and air; therefore, it plays a key role in plants’ interactions with their surroundings. It is also unstable and susceptible to light intensity.
Ping Guan   +6 more
doaj   +1 more source

An Optical Microscope Study of the Morphology of Xenon Hydrate Crystals: Exploring New Approaches to Cryopreservation

open access: yesCrystals, 2019
One of the possible approaches to a new method of cryopreservation seems to be the controlled formation of a multitude of small crystals in an object, which, due to their size, will not damage cellular structures.
Alexey Kobelev   +6 more
doaj   +1 more source

Morphological and Surface Microtopographic Features of HPHT-Grown Diamond Crystals with Contact Twinning

open access: yesCrystals, 2022
Gem-grade twinned high-pressure high-temperature (HPHT) synthetic diamond crystals are rare. Hence, few investigations on their morphological features and formation have been reported.
Kaiyue Sun   +5 more
doaj   +1 more source

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