Results 51 to 60 of about 518,016 (300)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Luminescent analysis of the quality of CdS nanocrystals depending on technological parameters
This work is devoted to luminescent investigations of CdS nanowhiskers grown in different technological approaches with variable parameters, what allows to control sizes and morphology of grown nanocrystals. Luminescence was used for the express analysis
A.B. Bogoslovskaya
doaj +1 more source
Crystal morphology plays a critical role in the processability and physicochemical behavior of active pharmaceutical ingredients. Manipulating crystal morphology involves consideration of crystallization conditions such as temperature, supersaturation ...
Nicolás Antonio Ramos Ojeda +1 more
doaj +1 more source
Toward a Comprehensive Model of Snow Crystal Growth: 6. Ice Attachment Kinetics near -5 C [PDF]
I examine a variety of snow crystal growth measurements taken at a temperature of -5 C, as a function of supersaturation, background gas pressure, and crystal morphology.
Libbrecht, Kenneth G.
core +1 more source
Morphology of Graphene on SiC(000-1) Surfaces
Graphene is formed on SiC(000-1) surfaces (the so-called C-face of the crystal) by annealing in vacuum, with the resulting films characterized by atomic force microscopy, Auger electron spectroscopy, scanning Auger microscopy and Raman spectroscopy ...
Feenstra, R. M. +7 more
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Free-standing exfoliated monolayer graphene is an ultra-thin flexible membrane, which exhibits out of plane deformation or corrugation. In this paper, a technique is described to measure the band structure of such free-standing graphene by angle-resolved
Alberto Morgante +10 more
core +1 more source
The physics of snow crystals [PDF]
We examine the physical mechanisms governing the formation of snow crystals, treating this problem as a case study of the dynamics of crystal growth from the vapour phase.
Libbrecht, Kenneth G.
core +2 more sources
Modification of Ceritinib Crystal Morphology via Spherical Crystallization
The formulation process for some drugs can be challenging, due to their unfavorable physical and mechanical properties and poor water solubility. Powder technology has made a significant impact in regard to the modification of the particles in active pharmaceutical ingredients (APIs) to produce high-quality granules.
Iva Zokić +5 more
openaire +3 more sources
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source

