Results 91 to 100 of about 19,580,563 (395)
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Crystal structure of binase does not reflect its native conformation
Учёные записки Казанского университета: Серия Естественные науки, 2018 Cytotoxic ribonucleases (RNases) of the T1 family, including binase, the secreted guanyl-preferring RNase of Bacillus pumilus, are considered as promising agents of alternative anticancer chemotherapy.
E.V. Dudkina +5 more
doaj
N1-[(1H-Imidazol-2-yl)methylidene]-N4-phenylbenzene-1,4-diamine
Acta Crystallographica Section E, 2014 The title compound, C16H14N4, is non-planar with dihedral angles between the planes of the imidazole and phenylenediamine rings of 30.66 (4)° and between the planes of the phenylenediamine and N-phenyl rings of 56.63 (7)°.
Md. Serajul Haque Faizi +3 more
doaj +1 more source
[1,1′-Bicyclohexane]-1,1′-diol
IUCrData, 2023 The title compound, C12H22O2, is a symmetric diol derived from the pinacol coupling of cyclohexanone. The asymmetric unit contains three complete molecules. The cyclohexane moieties adopt chair conformations.
Zukisani Mtendeni +2 more
doaj +1 more source
Crystal structure of barium oxonitridophosphate, Ba3P6O6N8 [PDF]
, 2011 Ba3N8O6P6, trigonal, P3 (no.
Schnick, Wolfgang +2 more
core +1 more source
The Crystal Structure of Topaz [PDF]
Proceedings of the National Academy of Sciences, 1928 An investigation of the orthorhombic crystal topaz, Al2SiO4F2, with x-rays has been reported by Leonhardt. With the aid of data from Laue and rotation photographs he found for the edges of the unit of structure, containing 4Al2SiO4F2, the values d100 = 4.64 A, d010 = 8.78 A, and d001 = 8.37 A, and determined the space-group of the crystal to be V16h. A
openaire +4 more sources
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Potassium 4-azidobenzenesulfonate
Acta Crystallographica Section E, 2014 In, K+·SO3–p-C6H4–N3−, the conformation angle of the azido group with respect to the benzene ring is 19.1 (3)°, so that the anion is chiral within the crystal structure. In addition, the crystal structure is also chiral (Sohncke space group).
Frank Biesemeier +3 more
doaj +1 more source
The structure of an orthorhombic crystal form of a 'forced reduced' thiol peroxidase reveals lattice formation aided by the presence of the affinity tag [PDF]
, 2012 Thiol peroxidase (Tpx) is an atypical 2-Cys peroxiredoxin, which has been suggested to be important for cell survival and virulence in Gram-negative pathogens.
Beckham, Katherine S.H. +3 more
core +1 more source
Crystal Structures of Furazanes [PDF]
Crystals, 2015 Several nitrogen-rich salts of 3-nitramino-4-nitrofurazane and dinitraminoazoxyfurazane were synthesized and characterized by various spectroscopic methods. The crystal structures were determined by low temperature single crystal X-ray diffraction. Moreover the sensitivities toward thermal and mechanical stimuli were determined by differential thermal ...
Klapötke, Thomas M. +2 more
openaire +4 more sources