Results 91 to 100 of about 3,520,724 (372)
The crystal structure of [PDF]
9 pages, 2 figures, 3 ...
Catrin Löhnert+2 more
openaire +2 more sources
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu+3 more
wiley +1 more source
Di-tert-butyl 1-[2-hydroxy-3-(methylsulfanyl)propyl]hydrazine-1,2-dicarboxylate
The title compound, C14H28N2O5S, was synthesized by the reaction of 2-[(methylsulfanyl)methyl]oxirane with di-tert-butyl oxalate in hydrazine hydrate. In the crystal, molecules are linked by N—H...O and O—H...O hydrogen bonds into supramolecular chains ...
Xiao-Guang Bai+2 more
doaj +1 more source
Metallo-Dielectric Photonic Crystals and Bandgap Blue-Shift [PDF]
One of the most appealing aspects of photonic crystal structures is the photonic bandgap created in structures with sufficiently high dielectric contrasts between constituent materials. Understanding how specific photonic crystal structures and their associated stopband positions can selectively interfere with incoming light is vital for implementing ...
arxiv
Tunability of wire-grid metamaterial immersed into nematic liquid crystal [PDF]
We propose electrically tunable hybrid metamaterial consisting of special wire grid immersed into nematic liquid crystal. The plasma-like permittivity of the structure can be substantially varied due to switching of the liquid crystal alignment by ...
de Jeu W. H.+2 more
core +2 more sources
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
5-Fluoro-2-(2-fluorophenyl)-3-methylsulfinyl-1-benzofuran
In the title compound, C15H10F2O2S, the dihedral angle between the plane of the benzofuran ring system (r.m.s. deviation = 0.015 Å) and that of the 2-fluorophenyl ring is 28.53 (6)°.
Hong Dae Choi, Pil Ja Seo, Uk Lee
doaj +1 more source
Gelfand-Tsetlin Crystals [PDF]
We give a crystal structure on the set of Gelfand-Tsetlin patterns which parametrize bases for finite-dimensional irreducible representations of the general linear Lie algebra. The crystal data are given in closed form, expressed using tropical polynomial functions of the entries of the patterns.
arxiv
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Crystal structure of binase does not reflect its native conformation
Cytotoxic ribonucleases (RNases) of the T1 family, including binase, the secreted guanyl-preferring RNase of Bacillus pumilus, are considered as promising agents of alternative anticancer chemotherapy.
E.V. Dudkina+5 more
doaj